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Trascriptome data in the brain from Propolis treated-Alzheimer's disease model mice

ABSTRACT: Trascriptome data in the brain from Propolis treated-Alzheimer's disease model mice

PROVIDER: PRJNA980123 | ENA |

REPOSITORIES: ENA

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Trascriptome data in the brain from Propolis treated-Alzheimer's disease model mice

Project description:We showed that Brazilian green propolis attenuated Aβ-induced memory and learning impairment. Comprehensive gene expression analysis demonstrated that Brazilian green propolis treatment suppressed inflammation and immune responses via immune cells such as microglia and astrocytes in the brain. These results indicate the potential of Brazilian green propolis as a promising ingredient for preventing AD-type dementia.

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Transcriptomic analysis of a propolis-resistant Saccharomyces cerevisiae strain obtained by evolutionary engineering

Project description:A propolis-resistant Saccharomyces cerevisiae mutant strain was obtained using an evolutionary engineering strategy based on successive batch cultivation under gradually increasing propolis levels. The mutant strain FD 11 was selected at a propolis concentration that the reference strain could not grow at all. Whole-genome transcriptomic analysis of FD11 was performed with respect to its reference strain to determine differences in gene expression levels between the two strains. Saccharomyces cerevisiae

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Age-dependent changes in phosphorylation of signaling molecules in brain tissues of Alzheimer's disease (AD) model mice

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