Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Correlation between gut microflora and reproductive performance in sows

PROVIDER: PRJNA985431 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR24972100_1.fastq.gz	Fastqsanger.gz
	SRR24972100_2.fastq.gz	Fastqsanger.gz
	SRR24972101_1.fastq.gz	Fastqsanger.gz
	SRR24972101_2.fastq.gz	Fastqsanger.gz
	SRR24972102_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 36

Similar Datasets

Exosome miRNA expression in umbilical cord blood of high-parity piglets reveals the reproductive potential of sows

Project description:The objective of modern pig breeding is to exhaust the genetic potential in reproduction performance of sows regarding to litter size and litter weight of piglets. During gestation period, umbilical cord contributes to placenta-fetal communication and plays an indispensable role in the intrauterine embryonic development. In this study, we attempted to analyze the molecular mechanism of reproductive declined in high-parity sows from the perspective of umbilical cord blood. Firstly, we analyzed the reproductive character data of sows, and then the histological analysis of umbilical cord phenotype was performed. Next, we evaluated the effect of umbilical cord blood exosomes (UCB-EXO) on angiogenesis. Moreover, the expression characteristics of miRNA in UCB-EXO of high-parity sows with poor reproductive performance (OS) and multiparous sows with excellent reproductive performance (MS) were analyzed. Results showed that the reproductive performance performed best at 3rd-7th and gradually decreased after 8th parities. Angiogenesis was repressed in OS piglets. Moreover, the Exo-MS exhibited pro-angiogenesis properties, with those of Exo-OS were diminished. With the increase of parities, the angiogenesis and immune function of sows decreased significantly, greatly limited the reproductive potential of sows. The data demonstrated that miRNAs of UCB-EXO played a central role in intrauterine development and suggested a novel possible explanation for reproductive potential, provides reference for increasing female reproductive efficiency.

2022-09-28 | GSE209805 | GEO

Synergistic Effects of High-Fiber Diet and N-Carbamylglutamate on Sow Reproductive Performance via Uterine Microbiota-PI3K/Akt Modulation

Project description:Landrace x Yorkshire sows were selected to investigate the synergistic effects of high fiber diet and 0.05% NCG on reproductive performance through transcriptomic analysis of endometrium samples.

2025-12-24 | GSE314489 | GEO

Dietary High Fiber and N-Carbamylglutamate Enhance Sow Reproductive Performance via Modulating Lactobacilli, Lipid Metabolites, and the PI3K-Akt Signaling Pathway

2025-12-23 | GSE313978 | GEO

gut microbiota

Project description:Jin hua sows with different reproductive performance

| PRJNA1118910 | ENA

Project description:Microbial Markers of Resilience and its Correlation with Reproductive Performance in Lactating Sows under Heat Stress Condition

| PRJNA1245056 | ENA

Exposure to copper compromises the maturational competency of porcine oocytes via oxidative stress-induced DNA damage

Project description:Copper (Cu) is not only one of the essential trace elements for animal body, but also an important nutrient component for normal physiology and metabolism of animal reproductive system. Lack or excess of copper will directly or indirectly affect animal reproductive activities. However, the effect of copper on reproductive performance of boars and sows has not been studied and the effect of excessive Copper addition on reproductive performance of sows is even less, and the molecular mechanism is poorly understood. Here, we document that copper has the negative effects on the oocyte maturation and Organelle function. We show that copper exposure perturbs the porcine oocyte meiotic maturation and impair the spindle/chromosome structure, displaying an obviously defective spindle assembly, and abnormal distribution of actin dynamics and cortical granules. In addition, single-cell transcriptome analysis identifies target effectors of copper in porcine oocytes, which was further demonstrated that copper exposure affects the distribution and function of mitochondria, and high ROS levels, DNA damage, and early apoptosis in porcine oocytes. Collectively, we demonstrate that copper exposure causes abnormalities in mitochondrial function and distribution, resulting in increased oxidative stress ROS levels, DNA damage and apoptosis, ultimately leading to decreased quality of porcine oocytes.

2021-06-28 | GSE168867 | GEO

Project description:The Mechanism of Quercetin Influencing Reproductive Performance in Perinatal Sows

| PRJNA968053 | ENA

Project description:Multi-omics Profiling of Gut-Serum Axis Dynamics in Gestational Sows with Different Reproductive Performance

| PRJNA1406678 | ENA

Project description:Multi-omics Profiling of Gut-Serum Axis Dynamics in Gestational Sows with Different Reproductive Performance

| PRJNA1413896 | ENA

Project description:Modified Bazhen improved reproductive performance and breast milk quality of sows.

| PRJNA755976 | ENA