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MetabolomicsProteomics reveals an increase in the abundance of glycolytic and ethanolic fermentation enzymes in developing sugarcane culms during sucrose accumulation
Not available
ORGANISM(S): Saccharum spp 
ST001879 | MetabolomicsWorkbench
MetabolomicsProteomics and tracer metabolomics link GAPDH ISGylation to glycolytic control

Ubiquitin-like protein ISG15 (interferon-stimulated gene 15) has been implicated in the regulation of central carbon metabolism, but conflicting findings across experimental systems have limited mechanistic insight. Here, we applied a multi-omics approach in cells ectopically expressing the ISGyl...

2026-03-02 | MTBLS12619 | MetaboLights
MetabolomicsMetabolite profiling of Arabidopsis mutants of enzymes of lower glycolysis
We have previously shown that in Arabidopsis the three enzymes of lower glycolysis phosphoglycerate mutase (PGAM), enolase and pyruvate kinase form a complex which play an important role in co-sub-cellar localization the mitochondria to the chloroplast. Given that their metabolites of these mutants,...
2022-10-10 | MTBLS4066 | MetaboLights
MetabolomicsPhysiological extremes of the human blood metabolome: A metabolomics analysis of highly glycolytic, oxidative, and anabolic athletes
Human metabolism is highly variable. At one end of the spectrum, defects of enzymes, transporters, and metabolic regulation result in metabolic diseases such as diabetes mellitus or inborn errors of metabolism. At the other end of the spectrum, favorable genetics and years of training combine to res...
2022-02-07 | MTBLS2104 | MetaboLights
TranscriptomicsTranscription profiling of S. cerevisiae treated with absence of oxygen or depletion of ATP to investigate control of glycolytic enzyme fluxes
Metabolic fluxes may be regulated "hierarchically," e.g., by changes of gene expression that adjust enzyme capacities (V(max)) and/or "metabolically" by interactions of enzymes with substrates, products, or allosteric effectors. In the present study, a method is developed to dissect the hierarchical...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-16 | E-GEOD-9232 | biostudies-arrayexpress
TranscriptomicsHIF1a-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells
Upon antigen stimulation, the bioenergetic demands of T cells increase dramatically over the resting state. Although a role for the metabolic switch to glycolysis has been suggested to support increased anabolic activities and facilitate T cell growth and proliferation, whether cellular metabolism c...
ORGANISM(S): Mus musculus 
2011-06-07 | E-GEOD-29765 | biostudies-arrayexpress
ProteomicsMitochondrial ROS-dependent localization and trafficking of glycolytic enzymes to mitochondria
Mitochondrial reactive oxygen species (mtROS) regulate cellular signaling pathways, but also cause oxidative stress when de-regulated during aging and pathological conditions such as neurodegenerative diseases. The dynamic trafficking of proteins between cellular compartments is a common mechanism t...
ORGANISM(S): Homo sapiens (Human) 
2025-08-12 | PXD066204 | Pride
Mitochondria Mts-dao Redox signaling Glycolytic enzymes Oxidative stress Dao 
ProteomicsGlycolytic Enzyme Coalesce in G bodies Under Hypoxic Stress
Glycolysis is upregulated in cells under specific conditions, such as hypoxia and high energy demand, to achieve the metabolic requirements for continued cell proliferation. However, the mechanism of this increased glycolytic rate remains poorly understood. In the budding yeast Saccharomyces cerevis...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2017-07-24 | PXD006686 | Pride
Hypoxia  glycolytic enzymes  rna granules  amp kinase  phosphorylation  saccharomyces cerevisiae  phosphofructokinase 
UnknownROS-dependent localization of glycolytic enzymes to mitochondria.
Not available
S-EPMC12359183 | biostudies-literature
ProteomicsHypoxia induces a glycolytic complex in intestinal epithelial cells independent of HIF-1-driven glycolytic gene expression Dataset2
The metabolic adaptation of eukaryotic cells to hypoxia involves increasing dependence upon glycolytic ATP production, an event with consequences for both cell bioenergetics and cell fate. This response is regulated at the transcriptional level by HIF-1-dependent transcriptional upregulation of all ...
ORGANISM(S): Homo sapiens (Human) 
2024-05-21 | PXD037020 | Pride
Metabolism Hypoxia Glucose metabolism Hif Glycolysis 
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