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ProteomicsThe interactome of human MIC13, a subunit of MICOS complex
Description: MIC13 is a subunit of the mitochondrial contact site and cristae organizing system (MICOS) and essential for mitochondrial cristae structure. Here we enriched Mic13 by co-Immunoprecipitation and identified interacting proteins.
ORGANISM(S): Homo sapiens (Human) 
2025-01-02 | PXD044968 | Pride
Micos Mib Mitochondria Lc-msms 
ProteomicsDiverged Trypanosome MICOS as a Hub for Mitochondrial Cristae Shaping and Protein Import
The mitochondrial contact site and cristae organization system (MICOS) is a complex responsible for proper cristae formation. Empirical data about this ubiquitous complex is limited to opisthokont models (e.g. yeast), impeding understanding of its core properties and adaptation potential to diverse ...
ORGANISM(S): Trypanosoma brucei 
2018-09-13 | PXD009601 | Pride
Mitochondria  cristae  intermembrane space  micos  protein import  trypanosoma brucei  lc-ms/ms  label-free  tmt 
ProteomicsMICOS and F1FO-ATP synthase crosstalk is a fundamental property of mitochondrial cristae
Mitochondrial cristae are polymorphic invaginations of the inner membrane that are the fabric of cellular respiration. Both the Mitochondrial Contact Site and Cristae Organization System (MICOS) and the F1FO-ATP synthase are vital for sculpting cristae by opposing membrane bending forces. While MICO...
ORGANISM(S): Trypanosoma brucei brucei TREU927 
2021-06-15 | PXD025109 | Pride
Micos Ip Lc-ms 
UnknownMulticolor 3D MINFLUX nanoscopy of mitochondrial MICOS proteins.
Not available
S-EPMC7456099 | biostudies-literature
UnknownThe evolution of MICOS: Ancestral and derived functions and interactions.
Not available
S-EPMC4802753 | biostudies-literature
UnknownMICOS coordinates with respiratory complexes and lipids to establish mitochondrial inner membrane architecture.
Not available
S-EPMC4434539 | biostudies-literature
UnknownA DRP-like pseudoenzyme coordinates with MICOS to promote cristae architecture.
Not available
S-EPMC10592917 | biostudies-literature
UnknownQIL1 mutation causes MICOS disassembly and early onset fatal mitochondrial encephalopathy with liver disease.
Not available
S-EPMC5021520 | biostudies-literature
UnknownMic60/Mitofilin determines MICOS assembly essential for mitochondrial dynamics and mtDNA nucleoid organization.
Not available
S-EPMC5072434 | biostudies-literature
ProteomicsComplexome profiling of MICOS complex, impact of subunits MIC26 and MIC27
Here we analysed the impact of two subunits (MIC26 and MIC27) on the assembly and stability of the mitochondrial contact site and cristae organizing system (MICOS) complex.
ORGANISM(S): Homo sapiens (Human) 
2020-07-28 | PXD016732 | Pride
Micos Oxidative phosphorylation system Lc-msms Complexome profiling 
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