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UVA radiation is one of the main harmful factor that penetrates all human skin layers and influencing communication between the cells that build them. To prevent UVA-induced damage, there is a constant search for compounds that could protect all skin cells, as well as restoring homeostasis in their ...
ORGANISM(S): Homo sapiens (Human) 
2026-08-24 | PXD071840 | Pride
Effect of Ascorbic acid on human genome
ORGANISM(S): Homo sapiens 
Aims: This study aims to assess the effect of simultaneous use of cannabigerol (CBG) and 3-O-ethyl ascorbic acid (EAA) on changes in the skin melanocyte proteome induced by UVA radiation, with particular emphasis on modifications in the structure of metabolically important proteins. Results: Proteom...
ORGANISM(S): Homo sapiens (Human) 
2026-06-15 | PXD074276 | Pride
The skin is a protective barrier against external insults and any lesion must be rapidly and efficiently repaired. Dermal fibroblasts are the major source of extracellular connective tissue matrix and play an important role in wound healing. Vitamin C is an important water-soluble free radical scave...
ORGANISM(S): Homo sapiens 
All samples are 50 day old cerebral organoids differentiated from human iPSCs using human the Lancaster protocol (Lancaster et al Nature Protoc, 2014). 4 samples are wild-type (WT) organoids derived from the iPSC line IPSO; 4 samples are Fragile X Syndrome (FX) organoids derived from the iPSC line F...
ORGANISM(S): Homo sapiens 
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