acute liver failure

Show results for

Unknown (2198)
Genomics (203)
Transcriptomics (183)
Proteomics (34)
Metabolomics (9)
Other (5)
Genomic (3)
Models (1)
Clinical (1)

Organisms

Mus musculus (104)
Homo sapiens (98)
Alphavirus (16)
Anemia (16)
Archaea (16)
Bacteria (16)
Betaherpesvirinae (16)
Borrelia (16)
Clostridium perfringens (16)
Cytomegalovirus (16)
Dengue virus (16)
Eukaryota (16)
Hepatitis B virus (16)
Human alphaherpesvirus 1 (16)
Human betaherpesvirus 5 (16)
Human immunodeficiency virus (16)
Influenza A virus (16)
Influenza C virus (16)
Japanese encephalitis virus group (16)
Kamptonema sp. (16)
Listeria monocytogenes (16)
Mammarenavirus (16)
Rattus norvegicus (15)
Bos taurus (2)
Drosophila melanogaster (1)
Danio rerio (1)
Pelophylax nigromaculatus (1)
Escherichia coli (1)
Mus (1)
Rattus rattus (1)

Organisms

Mus musculus (63)
Homo sapiens (57)
Rattus norvegicus (4)
rat gut metagenome (2)
adeno-associated virus 2 (1)
Algoriphagus (1)
Plasmodium falciparum 3D7 (1)
Pelophylax nigromaculatus (1)
human blood metagenome (1)
Severe acute respiratory syndrome coronavirus 2 (1)
Homo (1)
Mus musculus domesticus (1)
human gut metagenome (1)

Repository

ENA (181)
geo (113)
biostudies-arrayexpress (90)
iProX (16)
pride (16)
MetaboLights (9)
EGA (4)
ExpressionAtlas (3)
dbGaP (3)
MassIVE (2)
BioModels (1)

Tissue

Liver (6)
Hepatocyte (4)
Blood serum (3)
Blood plasma (2)
Cell culture (1)
Monocyte (1)

Disease

Normal (3)
Acute liver failure (2)
Hepatitis B virus associated acute liver failure (1)
Liver hemangioma (1)
Advanced gastrointestinal cancers (1)
Cardiovascular system disease (1)
Disease free (1)
Fatty liver disease (1)
Liver cirrhosis (1)
Liver disease (1)
Wounds and Injuries (1)

Technology Type

Mass Spectrometry (16)
Shotgun proteomics (9)
Mass spectrometry (7)
Illumina HiSeq 2000 (1)
NMR spectroscopy assay (1)
Mass spectrometry assay (1)
Affinity purification coupled with mass spectrometry proteomics (1)
Bottom-up proteomics (1)
Data-independent acquisition (1)
Gel-based experiment (1)
MSE (1)
SRM/MRM (1)
SWATH MS (1)
Top-down proteomics (1)

Instrument Platform

Liquid Chromatography MS - positive - reverse phase (5)
Liquid Chromatography MS - negative - reverse phase (5)
NextSeq 500 (3)
ShARC (1)
Agilent 2100 (1)
Chromium Single Cell 3’ Reagent kits v2 (1)
Illumina NovaSeq X (1)
Illumina HiSeq 2500 (1)
Illumina NovaSeq 6000 (1)
Illumina HiSeq 2000 (1)
Illumina HiSeq 4000 (1)
Q Exactive (1)
TripleTOF 5600 (1)
Nuclear Magnetic Resonance (NMR) - - - Varian (1)
Nuclear Magnetic Resonance (NMR) - - - Bruker (1)
Liquid Chromatography MS - positive - reverse-phase (1)
Liquid Chromatography MS - negative - reverse-phase (1)
Liquid Chromatography MS - negative - hilic (1)
Liquid Chromatography MS - positive - hilic (1)

Publication Date

2024 (30)
2025 (27)
2026 (22)
2021 (22)
2015 (18)
2013 (16)
2023 (16)
2020 (13)
2012 (12)
2008 (9)
2022 (9)
2014 (8)
2010 (8)
2019 (7)
2016 (7)
2018 (6)
2011 (6)
2009 (4)
2017 (4)
2007 (3)
2006 (1)

UNIPROT ID/AC

Q969J5 (1)
Q08334 (1)
P52294 (1)
Q9GZX6 (1)
Q8N6P7 (1)
P08887 (1)
P40189 (1)
O14543 (1)
P42224 (1)
P40763 (1)
P05231 (1)
Q06124 (1)
O15524 (1)

CHEBI ID

CHEBI:15428 (4)
CHEBI:15611 (3)
CHEBI:27570 (3)
CHEBI:18257 (3)
CHEBI:24898 (3)
CHEBI:30794 (3)
CHEBI:1148 (3)
CHEBI:15891 (3)
CHEBI:17368 (3)
CHEBI:20067 (3)
CHEBI:50392 (2)
CHEBI:73018 (2)
CHEBI:30813 (2)
CHEBI:42504 (2)
CHEBI:27389 (2)
CHEBI:17992 (2)
CHEBI:27386 (2)
CHEBI:15584 (2)
CHEBI:33508 (2)
CHEBI:18101 (2)
CHEBI:60645 (2)
CHEBI:81244 (2)
CHEBI:16325 (2)
CHEBI:16755 (2)
CHEBI:17822 (2)
CHEBI:16680 (2)
CHEBI:26271 (2)
CHEBI:25094 (2)
CHEBI:18237 (2)
CHEBI:16991 (1)

Metabolite Name

Hypoxanthine (4)
P-Hydroxyphenylacetic acid (3)
Oxoglutaric acid (3)
Chenodeoxycholic acid (3)
Succinic acid (3)
Pantothenic acid (3)
Glyceric acid (3)
Adipic acid (3)
2,4-Dinitrophenol (2)
Sn-Glycero-3-phosphocholine (2)
Alpha-Linolenic acid (2)
P-Cresol (2)
Alpha-ketoisovaleric acid (2)
Hyocholic acid (2)
Threonic acid (2)
3-Methylthiopropionic acid (2)
2-Ketobutyric acid (2)
4-Hydroxyphenylpyruvic acid (2)
Ketoleucine (2)
Pentadecanoic acid (2)
2-Hydroxy-3-methylbutyric acid (2)
Glycine (2)
ATP (2)
AMP (2)
Salicyluric acid (2)
Phenylacetic acid (2)
Betaine (2)
Pyroglutamic acid (2)
Niacinamide (2)
L-Lysine (2)

First Public Date

2024 (29)
2026 (26)
2025 (22)
2021 (21)
2023 (15)
2020 (13)
2019 (11)
2014 (11)
2022 (10)
2018 (7)
2017 (7)
2016 (4)
2015 (4)
2013 (1)

Modelling Approach

Petri net (1)

Study status

Recruiting (1)

Lab affiliation

BK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu 41566, Republic of Korea (2)
1Dept. of Pharmacology and Toxicology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205 2Dept. of Environmental and Occupational Health, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, Little Rock, AR 72205 (1)
Chemistry department, University of Quebec at Montreal (UQAM) (1)
Chinese Academy of Sciences Shanghai Institute of Materia Medica (1)
Department of Biology, University of Konstanz, Universitaetsstrasse 10, 78457 Konstanz (1)
Department of Pharmaceutical Sciences Northeast Ohio Medical University Rootstown, OH, USA MTD project_title Proteome dynamics in dogs with heart failure (1)
Goliver Therapeutics (1)
High-Throughput Biological Sciences, Department of Chembical Biology & Therapeutics, St. Jude Children's Research Hospital (1)
Medical Department III, Gastroenterology, Metabolic diseases and Intensive Care, University Hospital RWTH Aachen, Aachen, Germany (1)
Metaheps GmbH, Germany Department of Medicine 2, Liver Centre MunichÂ®, University Hospital Munich (KUM) Campus Grosshadern, Munich, Germany, Germany (1)
Northeastern University (1)
Proteomics Service CIC bioGUNE Bizkaia Tech. Park Build. 800 48160 Derio (Spain) (1)
Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Lisbon, Portugal rvitorino@ua.pt iBiMED- Department of Medical Siences University of Aveiro (1)
The Affiliated Hospital of Jiaxing University (1)
Wuhan University (1)

IsPrivate

False (1)

Classification

viruses (2)
protozoa (1)

Study type

Transcription profiling by array (65)
RNA-seq of coding RNA (12)
ChIP-seq (4)
RNA-seq of coding RNA from single cells (4)
Methylation profiling by array (2)
Genotyping by array (1)
Other (1)
RNA-seq of total RNA (1)
Interventional (1)

Release Date

2022 (296)
2021 (291)
2023 (276)
2025 (247)
2024 (204)
2020 (200)
2019 (139)
2018 (113)
2016 (99)
2017 (92)
2015 (78)
2014 (51)
2013 (46)
2026 (39)
2012 (35)
2010 (20)
2011 (18)
2008 (15)
2009 (10)
2007 (8)
2006 (2)
2005 (2)
2004 (2)
2003 (2)
2002 (2)
2000 (1)

Location

Australia (1)

Previous page
1 / 264
You're on page 1
page 2
page 3
page 4
page 5
page ...
page 264
Next page

Sort by:

Relevance

Page size

First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure

Diminished hepatocyte regeneration is a key feature of acute and chronic liver diseases and after extended liver resections, resulting in the inability to maintain or restore a sufficient functional liver mass. Therapies to restore hepatocyte regeneration are lacking, making liver transplantation...

2024-09-23 | MTBLS9434 | MetaboLights

Liver Regeneration Gene Signature in Hepatitis B virus (HBV)-Associated Acute Liver Failure Identified by Gene Expression Profiling

The liver has inherent regenerative capacity via mitotic division of mature hepatocytes. However, if the hepatic loss is massive or mature hepatocyte proliferation is impaired by chronic liver injury, HSPC are activated to support liver regeneration. Access to liver tissue from 4 patients who underw...

ORGANISM(S): Homo sapiens

2012-12-01 | E-GEOD-38941 | biostudies-arrayexpress

Role of Humoral Immunity against Hepatitis B Virus Core Antigen in the Pathogenesis of Acute Liver Failure

To investigate the role of viral and host factors in acute liver failure, we analyzed serum and multiple liver specimens obtained at the time of liver transplantation from four well-characterized patients. We carried out an integrated clinicopathological analysis, gene and microRNA expression profil...

ORGANISM(S): Homo sapiens

2018-10-29 | E-GEOD-96851 | biostudies-arrayexpress

B-Cell Gene Signature with Massive Intrahepatic Production of Antibodies to Hepatitis B Core Antigen in HBV-Associated Acute Liver Failure

Hepatitis B virus (HBV)-associated acute liver failure (ALF) is a dramatic clinical syndrome due to a sudden loss of hepatic cells leading to multiorgan failure. The mechanisms whereby HBV induces ALF are unknown. We used gene expression profiling to establish a molecular definition of hepatitis B v...

ORGANISM(S): Homo sapiens

2010-04-26 | E-GEOD-14668 | biostudies-arrayexpress

Proteomics Indicates Lactate Dehydrogenase is Prognostic in Acetaminophen-induced Acute Liver Failure Patients and Reveals a Role for LKB1-AMPK Signaling

Better biomarkers to predict death early in acute liver failure (ALF) are needed. To that end, we obtained early (study day 1) and later (day 3) serum samples from transplant-free survivors (n=28) and non-survivors (n=30) of acetaminophen (APAP)-induced ALF from the NIH-sponsored Acute Liver Failure...

ORGANISM(S): Homo sapiens (Human)

2022-08-12 | PXD029576 | Pride