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TranscriptomicsMultiple genes at the chromosome 20q amplicon contribute to colorectal adenoma to carcinoma progression
Chromosomal instability (CIN) is the hallmark of colorectal adenoma to carcinoma progression in 85% of cases, with 20q gain as the most prominent aberration. Yet, the oncogenes at this chromosomal gain are still largely unknown. Here, we aimed to identify oncogenes at 20q involved in colorectal aden...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-8067 | biostudies-arrayexpress
ProteomicsUTP18 as an oncogene promotes colorectal adenoma to carcinoma progression
Colorectal cancer often develops slowly from adenoma. In this study, we aimed to identify the oncogenes involved in the progression of colorectal adenoma to carcinoma by Tandem Mass Tag (TMT)-based quantitative proteomics. Protein expression changes were compared by TMT-based quantitative mass spect...
ORGANISM(S): Homo Sapiens 
2020-06-01 | PXD017068 |
GenomicsUTP18 as an oncogene promotes colorectal adenoma to carcinoma progression
UTP18 as an oncogene promotes colorectal adenoma to carcinoma progression
PRJNA595591 | ENA
TranscriptomicsModeling oncogenic signaling in colon tumors by multidirectional analyses of microarray data
Background. Most colorectal cancers (CRC) arise in a progression through adenoma to carcinoma phenotypes as a consequence of altered genetic information. Clinical progression of CRC may occur in parallel with distinctive signaling alterations. We designed multidirectional analyses integrating microa...
ORGANISM(S): Homo sapiens 
2010-08-01 | E-GEOD-20916 | biostudies-arrayexpress
TranscriptomicsMultiple genes at the chromosome 20q amplicon contribute to colorectal adenoma to carcinoma progression
Chromosomal instability (CIN) is the hallmark of colorectal adenoma to carcinoma progression in 85% of cases, with 20q gain as the most prominent aberration. Yet, the oncogenes at this chromosomal gain are still largely unknown. Here, we aimed to identify oncogenes at 20q involved in colorectal aden...
ORGANISM(S): Homo sapiens 
2008-10-15 | GSE8067 | GEO
GenomicsColorectal adenomas and carcinomas NKI-AvL TGO series Gut2009
Colorectal cancer (CRC) develops from normal epithelium, through a benign precursor lesion called adenoma, by accumulation of genetic alterations affecting oncogenes and tumour suppressor genes. These CRC-related genomic alterations often result in specific RNA-expression patterns. RNA isolated from...
EGAS00001002758 | EGA
MetabolomicsThe Cancer-Associated Microbe Library reveals functional host-microbe interactions during colorectal cancer progression

Functional characterization of microbes which colonize CRC is impeded by a lack of bacterial strains from tumor tissues. Here, we report the Cancer-Associated Microbe Library (CAM-L), comprising more than 3,000 viable bacterial isolates, representing 121 distinct species, and 60 matching organoid...

2026-02-08 | MTBLS7385 | MetaboLights
UnknownLumican and versican protein expression are associated with colorectal adenoma-to-carcinoma progression.
Not available
S-EPMC5421768 | biostudies-literature
GenomicsHomo sapiens
Multiple genes at the chromosome 20q amplicon contribute to colorectal adenoma to carcinoma progression
PRJNA100903 | ENA
UnknownOncogenic Role of miR-15a-3p in 13q Amplicon-Driven Colorectal Adenoma-to-Carcinoma Progression.
Not available
S-EPMC4492490 | biostudies-literature
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