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TranscriptomicsFunctional Genomics Analysis of the Yeast Iron Responsive Transcription Factor Aft1 Reveals Iron-Independent Functions
The Saccharomyces cerevisiae transcription factor Aft1 is activated in iron-deficient cells to induce the expression of iron regulon genes, which coordinate the increase of iron uptake and remodel cellular metabolism to survive low iron conditions. In addition, Aft1 has been implicated in numerou...
ORGANISM(S): Saccharomyces cerevisiae 
2010-05-01 | E-GEOD-20531 | biostudies-arrayexpress
TranscriptomicsTranscriptional effect of aft1 and aft2 mutation in iron depleted conditions
The paralogous transcription factors Aft1p and Aft2p activate the expression of genes involved in iron metabolism under iron depleted conditions. Both are able to bind to the same DNA consensus sequence in vitro. We used DNA microarrays and loss of function mutant strains to better understand the re...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-09 | E-GEOD-1763 | biostudies-arrayexpress
UnknownPichia pastoris Aft1--a novel transcription factor, enhancing recombinant protein secretion.
Not available
S-EPMC4161868 | biostudies-literature
TranscriptomicsFunctional Genomics Analysis of the Yeast Iron Responsive Transcription Factor Aft1 Reveals Iron-Independent Functions
The Saccharomyces cerevisiae transcription factor Aft1 is activated in iron-deficient cells to induce the expression of iron regulon genes, which coordinate the increase of iron uptake and remodel cellular metabolism to survive low iron conditions. In addition, Aft1 has been implicated in numerous c...
ORGANISM(S): Saccharomyces cerevisiae 
2010-05-01 | GSE20531 | GEO
UnknownNitric oxide prevents Aft1 activation and metabolic remodeling in frataxin-deficient yeast.
Not available
S-EPMC5602528 | biostudies-literature
UnknownFunctional genomics analysis of the Saccharomyces cerevisiae iron responsive transcription factor Aft1 reveals iron-independent functions.
Not available
S-EPMC2900968 | biostudies-literature
TranscriptomicsAft2 in yeast iron regulation
Iron homeostasis in the yeast Saccharomyces cerevisiae is regulated at the transcriptional level by Aft1p, which activates the expression of its target genes in response to low-iron conditions. The yeast genome contains a paralog of AFT1, which has been designated AFT2. To establish whether AFT1 and...
ORGANISM(S): Saccharomyces cerevisiae 
2005-08-13 | E-GEOD-3122 | biostudies-arrayexpress
UnknownAft1 Nuclear Localization and Transcriptional Response to Iron Starvation Rely upon TORC2/Ypk1 Signaling and Sphingolipid Biosynthesis.
Not available
S-EPMC9916926 | biostudies-literature
UnknownDirect activation of genes involved in intracellular iron use by the yeast iron-responsive transcription factor Aft2 without its paralog Aft1.
Not available
S-EPMC1190354 | biostudies-literature
UnknownRad9 interacts with Aft1 to facilitate genome surveillance in fragile genomic sites under non-DNA damage-inducing conditions in S. cerevisiae.
Not available
S-EPMC4227768 | biostudies-literature
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