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TranscriptomicsGene expression profiling of the tongue bud from Alk5 mutant mouse models
The overall goal of this project is to investigate the role of TGF-beta signaling in tissue-tissue interactions between myogenic precursors of craniofacial muscles and cranial neural crest cells (CNCCs). Here, we conducted gene expression profiling of the tongue bud from mice at embryonic day E13.5 ...
ORGANISM(S): Mus musculus 
2014-06-18 | E-GEOD-52358 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of the mandibular arch from Alk5 mutant mouse models
The overall goal of this project is to investigate the role of TGF-beta signaling in tissue-tissue interactions between myogenic precursors of craniofacial muscles and cranial neural crest cells (CNCCs). Here, we conducted gene expression profiling of the mandibular arch from mice at embryonic day E...
ORGANISM(S): Mus musculus 
2014-06-18 | E-GEOD-52357 | biostudies-arrayexpress
TranscriptomicsTGFbeta signalling in fibroblasts.
Murine embryonic fibroblasts, wild type or Alk5 knock outs, stimulated and unstimulated with TGFbeta.
ORGANISM(S): Mus musculus 
2010-06-10 | E-GEOD-1742 | biostudies-arrayexpress
TranscriptomicsActivation of TGF-beta pathway by areca nut constituents: A possible cause of Oral submucous fibrosis.
To understand the role of areca nut constituents in manifestation of Oral submucous fibrosis, we studied gene expression profile in epithelial cells following areca nut water extract treatment. A comaprison with TGF-beta induced gene expression changes were performed as epithelial cells were predict...
ORGANISM(S): Homo sapiens 
2013-05-22 | E-GEOD-38227 | biostudies-arrayexpress
GenomicsDetermine the role of ALK5 signaling in human brain pericytes treated with TGFβ.
Determine the role of ALK5 signaling in human brain pericytes treated with TGFβ.
PRJNA1120049 | ENA
GenomicsDetermine the role of ALK5 signaling in murine brain pericytes at embryonic day E13.5
Determine the role of ALK5 signaling in murine brain pericytes at embryonic day E13.5
PRJNA1117836 | ENA
UnknownThe endometrial cancer A230V-ALK5 (TGFBR1) mutant attenuates TGF-β signaling and exhibits reduced in vitro sensitivity to ALK5 inhibitors.
Not available
S-EPMC11584080 | biostudies-literature
UnknownEfficacy of ALK5 inhibition in myelofibrosis.
Not available
S-EPMC5374075 | biostudies-literature
UnknownLumican Peptides: Rational Design Targeting ALK5/TGFBRI.
Not available
S-EPMC5299588 | biostudies-literature
UnknownEndoglin and Alk5 regulate epithelial-mesenchymal transformation during cardiac valve formation.
Not available
S-EPMC2001167 | biostudies-literature
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