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TranscriptomicsGENE-EXPRESSION ANALYSIS RELATED TO OLIVE POLLEN ALLERGY
Analysis of gene-expression profiles by microarrays can be very useful to characterize new potential candidate genes, key regulatory networks, and to define phenotypes or molecular signatures to improve the diagnosis or classification of the disease. We have used this approach in the study of one of...
ORGANISM(S): Homo sapiens 
2013-02-28 | E-GEOD-37157 | biostudies-arrayexpress
TranscriptomicsTranscriptome Analysis Predicts Clinical Outcome and Sensitivity to Anticancer Drugs of patients with a Pancreatic Adenocarcinoma
A major impediment to the effective treatment of patients with PDAC (Pancreatic Ductal Adenocarcinoma) is the molecular heterogeneity of the disease, which is reflected in an equally diverse pattern of clinical responses to therapy. We developed an efficient strategy in which PDAC samples from 17 co...
ORGANISM(S): Homo sapiens 
2015-04-09 | E-GEOD-55513 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse lung to study the effect of prostaglandin E receptor subtype EP3 on mouse asthma model.
We examined the effect of PGE receptor EP3 subtype on mouse OVA-induced asthma model. We treat EP3 agonist 3h after OVA challenge. After 24 h of 3rd OVA challenge, whole lung was isolated and the gene expression change was determined.
ORGANISM(S): Mus musculus 
2007-09-25 | E-GEOD-2276 | biostudies-arrayexpress
UnknownEffects of non-steroidal anti-inflammatory drugs and other eicosanoid pathway modifiers on antiviral and allergic responses: EAACI task force on eicosanoids consensus report in times of COVID-19.
Not available
S-EPMC9111413 | biostudies-literature
UnknownTreatment of allergic asthma: modulation of Th2 cells and their responses.
Not available
S-EPMC3179723 | biostudies-literature
MetabolomicsMetabolomic analysis reveals a differential adaptation process of the larval stages of Anisakis simplex to the host environment

Anisakis simplex are parasitic nematodes that cause anisakiasis. The possibility of infection with this parasite is through consumption of raw or undercooked fish products. A. simplex infections are often misdiagnosed, especially in subclinical cases that do not present with typ...

2023-07-08 | MTBLS6458 | MetaboLights
ProteomicsAMOXICILLIN HAPTENATION OF α-ENOLASE
Allergic reactions to antibiotics are a major concern in the clinic, with almost 15% of the patients presenting with adverse reactions against β-lactam antibiotics. One of the mechanisms involved in this outcome is the modification of proteins by covalent binding of the drug (haptenation). Hence, th...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD029712 | Pride
Β-lactam antibiotics  protein modification by drugs  mass spectrometry  posttranslational modifications  acetylation  allergic responses to drugs 
MetabolomicsAntibiotics create a shift from mutualism to competition in human gut communities with a longer-lasting impact on fungi than bacteria

Background

Antibiotic treatment has a well-established detrimental effect on the gut bacterial composition, but effects on the fungal community are less clear. Bacteria in the lumen of the gastrointestinal tract may limit fungal colonization and invasion. Antibiotic drugs t...

2020-09-28 | MTBLS1846 | MetaboLights
UnknownThe Use of Bruton's Tyrosine Kinase Inhibitors to Treat Allergic Disorders.
Not available
S-EPMC8050815 | biostudies-literature
UnknownProstaglandin I2 Suppresses Proinflammatory Chemokine Expression, CD4 T Cell Activation, and STAT6-Independent Allergic Lung Inflammation.
Not available
S-EPMC4992670 | biostudies-literature
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