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MetabolomicsOvothiol A is the Main Antioxidant in Fish Lens
Tissue protection from oxidative stress by antioxidants is of vital importance for cellular metabolism. The lens mostly consists of fiber cells lacking nuclei and organelles, having minimal metabolic activity; therefore, the defense of the lens tissue from the oxidative stress strongly relies on met...
2019-07-30 | MTBLS806 | MetaboLights
MetabolomicsVariety-Specific Polyphenol Accumulation and Antioxidant Activity Differences in Apple Fruits

Oxidative stress is a key inducer of chronic diseases, and apple polyphenols exhibit significant antioxidant potential. This study systematically analyzed polyphenol accumulation characteristics and antioxidant activity of four apple cultivars (Qincui, Jiuyue Qiji, Orin, Ruixue) using a multi-lev...

2026-01-14 | MTBLS13681 | MetaboLights
MetabolomicsAccumulation Characteristics of Flavonoids and Contribution to Antioxidant Capacity in Wild and Cultivated Kiwifruits

This study aimed to clarify flavonoids accumulation characteristics and their contribution to antioxidant capacity in wild type (WT) kiwifruit (Actinidia deliciosa) and three cultivated varieties (Xuxiang, XX; Yazui, YZ; Hongyang, HY). Integrating untargeted metabolomics and traditional biochemic...

2026-01-14 | MTBLS13683 | MetaboLights
MetabolomicsButyric acid derived from porcine-derived antioxidant probiotic PGM326 enhances intestinal cell differentiation by promoting oxidative phosphorylation

This study not only identified an efficient host-homologous antioxidant probiotic, PGM326, but also systematically elucidated its mechanism of exerting antioxidant function by synthesizing BA to promote OXPHOS in intestinal epithelial cells, thereby enhancing cell differentiation. This provides a...

2026-02-01 | MTBLS13818 | MetaboLights
MetabolomicsEffects of Centella asiatica extract on antioxidant status and liver metabolome of rotenone-treated rats using GC-MS
The standardized extract of Centella asiatica (ECa233) contains >80% triterpenoids with a ratio of madecassoside to asiaticoside of 1.5(±0.5):1. Hepatoprotective effect of ECa233 has not yet been reported. The aim of this study was to examine the effect of ECa233 on liver metabolome of rotenone-trea...
2018-10-11 | MTBLS522 | MetaboLights
MetabolomicsResearch on the quality markers of antioxidant activity of Kai-Xin-San based on spectrum-effect relationship
Kai-Xin-San (KXS) is one of the classic famous traditional Chinese medicine prescriptions for amnesia, which has been applied for thousands of years. Modern pharmacological research has found that KXS has significant therapeutic efficacy on nervous system diseases, which is related to its antioxidan...
2023-12-21 | MTBLS8806 | MetaboLights
MetabolomicsRectal microbiomes and serum metabolomics reveal changes in serum antioxidant status and immune responses of Dezhou donkeys in late gestation to parturition

Background: Parturition is a critical event in the reproductive cycle of dairy animals, accompanied by multiple physiological changes in sex hormones, metabolism, antioxidant capacity and immune function. However, the changes in the rectal microbiota and metabolic products of Jennies from late ge...

2025-08-27 | MTBLS12897 | MetaboLights
MetabolomicsBiological Potential of Lophosoria quadripinnata Fern Extract: Integration of UHPLC/ESI/QToF/MS Analysis, Antioxidant Activity, Molecular Docking and Molecular Dynamics Simulation

Lophosoria quadripinnata (J.F.Gmel.) C.Chr., a fern species from the Dicksoniaceae family, is widely distributed in Central and South America. This study aimed to identify the bioactive compounds in the aqueous extract of L. quadripinnata, evaluate its antioxidant potential through in vitro analy...

2025-06-27 | MTBLS9336 | MetaboLights
MetabolomicsHow Does the Seed Pre-germinative Metabolism Fight against Imbibition Damage? Emerging Roles of Fatty Acid Cohort and Antioxidant Defence

During seed imbibition, lipids are engaged in membrane reorganization while facing free radical-mediated oxidative injury. In the present work, we explored changes in lipid components at different timepoints of imbibition (0.5, 2, 4, 6, and 8 h) in the legume Medicago truncatula, by combining bio...

2019-10-14 | MTBLS181 | MetaboLights
MetabolomicsMicrobiome-metabolome reveals rhizosphere ecology, bioactives and antioxidant shifts in Paeonia lactiflora Pall under intercropping and harvest periods
Paeonia lactiflora Pall (P. lactiflora) is a plant with medicinal and economic value; during its growth, root secondary metabolism and rhizosphere microbes interact, but no systematic study has examined microbiome and metabolome changes under different planting and harvest times; to address this, we...
2026-07-23 | MTBLS15141 | MetaboLights
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