attenuation mechanism

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Metabolite Name

AcCa(18:0)+H (1)
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Lab affiliation

Proteomics and Metabolomics Core Facility, Biomedical Research Institute, Seoul National University Hospital (2)
Boston University School of Medicine (1)
Cell Cycle and Genome Stability Group. Institute of Functional Biology and Genomics (IBFG). Spanish National Research Council (CSIC). University of Salamanca (USAL). C/ Zacarías González 2. Salamanca 37007. SPAIN (1)
Center for Molecular Biology of Heidelberg University (ZMBH), DKFZ-ZMBHAlliance, Im Neuenheimer Feld 282, D-69120 Heidelberg, Germany (1)
Centre for Engineering Biology, School of Biological Sciences, University of Edinburgh, United Kingdom (1)
Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, 233 S 10th Street, BLSB 826, Philadelphia, PA, 19104 (1)
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Department of Urology, 2 Department of Biochemistry and Molecular Biology, 3 Upstate Cancer Center, 4 College of Medicine SUNY Upstate Medical University Syracuse, NY, USA (1)
Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9RQ, United Kingdom (1)
Institute of Microbiology of the CAS; BIOCEV, Průmyslová 595, Vestec, Czech Republic (1)
Institute of Physiology of the Czech Academy of Sciences Laboratory of Bioenergetics (1)
La Laguna University. Dpto. Biología Celular, Microbiología, Genética y Bioquímica. 3ª Planta, Edificio de Sec. Facultad de Farmacia Apartado 456 Campus de Anchieta, 4. CP 38200. San Cristóbal de La Laguna. S/C de Tenerife Spain (1)
Laboratory of Antibiotic Resistance and Microbial Metabolomics, Kamenik & Balikova Novotna Lab, Institute of Microbiology of the Czech Academy of Sciences, Czech Republic (1)
Senior Postdoctoral Fellow Lew Laboratory Immunology Division The Walter and Eliza Hall Institute, Australia (1)
Shenyang Agricultural University (1)
State Key Laboratory of Developmental Biology of Freshwater Fish, College of Life Science, Hunan Normal University, Changsha, 410081, P. R. China. (1)
Sun Yat-sen Memorial Hospital,Sun Yat-sen University 107 Yanjiang West Road Guangzhou 510120, P. R. China (1)
University of Greifswald Institute of Microbiology Department of Microbial Proteomics Felix-Hausdorff-Str.8 17489 Greifswald (1)

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Schisandra chinensis alleviates dextran sulfate sodium-induced colitis in association with remodeling of a Parabacteroides goldsteinii-related leucine– isovalerate metabolic axis and attenuation of mTOR/HIF-1α/IL-17 signaling

Ulcerative colitis (UC) involves epithelial injury, gut microbial dysbiosis, disturbed microbial metabolism, and mucosal inflammation. This study evaluated the protective effect of Schisandra chinensis (SC) against dextran sulfate sodium (DSS)-induced UC and investigated the underlying microbiota...

2026-08-29 | MTBLS15496 | MetaboLights

Translocational attenuation regulated by PERK-SRP14 axis is a novel protective mechanism of UPR

ORGANISM(S): Homo Sapiens

PXD052453 |

Mechanism of virus attenuation by codon pair deoptimization

PRJNA556267 | ENA

Translocational attenuation regulated by PERK-SRP14 axis is a novel protective mechanism of UPR

PRJNA1114086 | ENA

Mechanism for local attenuation of DNA replication at double-strand breaks

PRJNA1069015 | ENA

Neuron signal attenuation activation mechanism for deep learning.

Not available

S-EPMC11783890 | biostudies-literature

Translocational attenuation regulated by PERK-SRP14 axis is a novel protective mechanism of UPR

Slowing down protein synthesis, increasing protein folding capability, and enhancing misfolded protein degradation are the main mechanisms of unfolded protein response (UPR) to lessen ER stress. It has also been shown that substrate-specific translocational attenuation may be another protective meas...

ORGANISM(S): Homo sapiens

2024-05-25 | GSE268040 | GEO

Affect of antiviral ribavirin on YFV WT and vaccine strains.

Live-attenuated viral vaccines have been successfully used to combat infectious disease for decades but due to their empirical derivation, little is known about their mechanisms of attenuation. This lack of understanding makes the development of next generation live attenuated vaccines difficult. Th...

ORGANISM(S): Yellow fever virus

2020-01-01 | E-MTAB-8504 | biostudies-arrayexpress

Novel chikungunya vaccine candidate with an IRES-based attenuation and host range alteration mechanism.

Not available

S-EPMC3145802 | biostudies-literature

Comparative Proteomics between Brucella abortus 2308 and Genetically Marked Vaccine A19ΔvirB12 Reveal Attenuation Mechanism and Supplementary Differential Diagnosis Antigens

Brucella abortus is an important zoonotic pathogen that causes severe economic loss to husbandry and poses a threat to human health. The B. abortus A19 live vaccine has been extensively used to prevent bovine brucellosis in China. However, A19 has the limitation of diagnosis interference and residua...

ORGANISM(S): Brucella abortus (strain 2308)

2021-09-09 | PXD022031 | Pride

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