autism - OmicsDI

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Repository

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Tissue

Brain (65)
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Autism spectrum disorder (29)
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Technology Type

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Instrument Platform

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- (4)
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Publication Date

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2008 (11)
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2005 (2)

CHEBI ID

CHEBI:16811 (5)
CHEBI:15428 (5)
CHEBI:28875 (5)
CHEBI:28842 (5)
CHEBI:17822 (4)
CHEBI:18237 (4)
CHEBI:15611 (4)
CHEBI:17750 (4)
CHEBI:17858 (4)
CHEBI:16680 (4)
CHEBI:15356 (1)
CHEBI:1989 (1)
CHEBI:15635 (1)
CHEBI:17515 (1)
CHEBI:27470 (1)
CHEBI:17724 (1)
CHEBI:16856 (1)
CHEBI:16240 (1)
CHEBI:18349 (1)
CHEBI:17230 (1)
CHEBI:15740 (1)
CHEBI:17622 (1)
CHEBI:18406 (1)
CHEBI:16842 (1)
CHEBI:15637 (1)
CHEBI:15641 (1)
CHEBI:15633 (1)
CHEBI:15414 (1)
CHEBI:16474 (1)
CHEBI:16526 (1)

Metabolite Name

Acetyl-CoA (2)
Histidine (2)
Adenine (2)
Valine (2)
NADPH (2)
Methionine (2)
Arginine (2)
Lysine (2)
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Alanine (2)
Threonine (2)
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Glutamine (2)
Glucose (2)
Tryptophan (2)
PE 46:3 (1)
PE 46:1 (1)
PE 44:8 (1)
PC e 46:0 (1)
PC e 42:6 (1)
PC e 42:10 (1)
PC e 40:9 (1)
PC e 40:8 (1)
PC e 40:7 (1)
PC e 40:6 (1)
PC e 40:5 (1)
PC e 40:4 (1)

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2022 (97)
2014 (90)
2019 (86)
2018 (61)
2017 (56)
2016 (42)
2015 (36)
2013 (35)

Modelling Approach

Ordinary differential equation model (1)

Study status

Terminated (1)
Not yet recruiting (1)
Recruiting (1)

Lab affiliation

Key Laboratory of Brain Functional Genomics of Shanghai and Ministry of Education, Institute of Brain Functional Genomics, School of Life Science and the Collaborative Innovation Center for Brain Science, East China Normal University, Shanghai, China (3)
Institute of Genetics & Developmental Biology, Chinese Academy of Sciences (2)
University Health Network, Krembil Research Institute (2)
VIB Center for Brain & Disease Research, Herestraat 49, 3000 Leuven, Belgium. (2)
Max Delbrück Center for Molecular Medicine in the Helmholtz association (MDC) Robert-Rössle-Straße 10 13125 Berlin (1)
Harvard Medical School Department of Neurobiology (1)
Department of Chemistry & Biomolecular Science Clarkson University, Potsdam, NY, 13699, Box 5810 (1)
Pathology and Laboratory Medicine, Genomic Medicine, Neurological and Pediatrics Institutes, Cleveland Clinic, Cleveland OH (1)
Stanford University School of Medicine 279 Campus Drive Stanford, CA 94305-5323 (1)
Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139 (1)
Bernstein Professor Emeritus in Adult Psychiatry Department of Psychiatry and Behavioral Sciences University of Minnesota Medical School Minneapolis, Minnesota, USA (1)
Laboratório de Biotecnologia e Biologia Molecular da Universidade Estadual do Ceará, Fortaleza, Ceará, Brazil. Departamento de Bioquímica e Biologia Molecular, Universidade Federal do Ceará, Fortaleza, Ceará, Brazil. (1)
Sch1School of Pharmacy, Department of Chemistry,University of Wisconsin-Madison, Madison, Wisconsin, 53705, (1)
Department of Neuroscience, Tufts University School of Medicine (1)
Genetic and Molecular Basis of Neurodevelopmental Disorders, IST Austria, Klosterneuburg, Lower Austria, Austria (1)
institute of genetics and developmental biology, Chinese Academy of Sciences (1)
School of Pharmacy, University of Wisconsin-Madison, Madison, WI, 53705, USA (1)
Department of Biomedical Science Centre for Membrane Interactions and Dynamics (CMIAD) Firth Court, Western Bank The University of Sheffield Sheffield S10 2TN United Kingdom (1)
Proteome Centre Tuebingen (1)
NeuroEpigenetics laboratory, Department of Cellular, Computational and Integrative Biology, University of Trento, Trento, Italy (1)
Institute for Human Genetics, University Medical Center Hamburg Eppendorf, Hamburg, Germany (1)
Department of Public Health and Medical Technology, Xiamen Medical College (1)
Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, 08028 Barcelona, Spain (1)
Hebrew University of Jerusalem (1)
Department of Laboratory Medicine and Pathobiology, University of Toronto (1)
MDC, Cellular Neuroscience Charitè, Ophthalmology (1)
SUNY Upstate Medical University Syracuse, NY, 13210 (1)
Center for Neuroscience Research, Children's National Hospital, Washington, DC. 20010 USA (1)
Institute of Neuroscience, College of Medicine, Xiamen University, Xiamen, Fujian, 361105, China (1)
State Key Laboratory of Medical Molecular Biology & Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences (1)

IsPrivate

False (1)

Classification

bacteria (1)

Study type

Transcription profiling by array (114)
RNA-seq of coding RNA (52)
Comparative genomic hybridization by array (20)
Methylation profiling by array (12)
ChIP-seq (11)
Methylation profiling by high throughput sequencing (6)
RNA-seq of coding RNA from single cells (5)
DNA-seq (4)
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Other (2)
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Observational (2)
Transcription profiling by SAGE (1)
Unknown experiment type (1)
Human - Two-color microarray (1)
Human - Single-cell sequencing (1)
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Capture-C (1)
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2007 (53)
2005 (19)
2006 (16)
2001 (10)
2002 (9)
2003 (8)
2004 (7)
2000 (1)

Location

United States (2)
Australia (1)

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Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice

Autism spectrum disorder (ASD) manifests as alterations in complex human behaviors including social communication and stereotypies. In addition to genetic risks, the gut microbiome differs between typically-developing (TD) and ASD individuals, though it remains unclear whether the microbiome contrib...

2019-07-04 | MTBLS726 | MetaboLights

Gut Microbiota and Urine Metabolomics Signature in Autism Spectrum Disorder children from Southern China

To determine the gut microbiota and urine metabolomics signature and identify the regional characteristics in Autism spectrum disorder (ASD), we conducted a cohort study of 88 well-characterized participants from Guangxi Zhuang Autonomous Region in Southern China. Gut microbiota and urine metabo...

2025-06-16 | MTBLS12605 | MetaboLights

Lactiplantibacillus plantarum PS128 restores microbiota-driven polyamine homeostasis to alleviate autism-like behaviors in Fmr1 knockout mice

Background: Autism spectrum disorder (ASD) is biologically heterogeneous and has limited mechanism-informed interventions targeting core behavioral symptoms. Emerging evidence suggests that gut microbial metabolism shapes neurobehavioral outcomes, yet the specific metabolic pathw...

2026-02-10 | MTBLS13881 | MetaboLights

Lactiplantibacillus plantarum PS128 restores microbiota-driven polyamine homeostasis to alleviate autism-like behaviors in Fmr1 knockout mice

Background: Autism spectrum disorder (ASD) is biologically heterogeneous and has limited mechanism-informed interventions targeting core behavioral symptoms. Emerging evidence suggests that gut microbial metabolism shapes neurobehavioral outcomes, yet the...

2026-02-07 | MTBLS13862 | MetaboLights

Lactiplantibacillus plantarum PS128 restores microbiota-driven polyamine homeostasis to alleviate autism-like behaviors in Fmr1 knockout mice

Background Autism spectrum disorder (ASD) is biologically heterogeneous and has limited mechanism-informed interventions targeting core behavioral symptoms. Emerging evidence suggests that gut microbial metabolism shapes neurobehavioral outcomes, yet the specific metabolic pathwa...

2026-02-06 | MTBLS13859 | MetaboLights

Investigation of post-transcriptional gene regulatory networks associated with autism spectrum disorders (ASD) by microRNA expression profiling of lymphoblastoid cell lines

Autism spectrum disorders (ASD) are neurodevelopmental disorders characterized by abnormalities in reciprocal social interactions and language development and/or usage, and by restricted interests and repetitive behaviors. Differential gene expression of neurologically relevant genes in lymphoblasto...

ORGANISM(S): Homo sapiens

2010-04-09 | E-GEOD-21086 | biostudies-arrayexpress

Gene expression profiling differentiates autism case-controls and phenotypic variants of autism spectrum disorders

Autism spectrum disorders (ASD) are neurodevelopmental disorders characterized by delayed/abnormal language development, deficits in social interaction, repetitive behaviors and restricted interests. The heterogeneity in clinical presentation of ASD, likely due to different etiologies, complicates ...

ORGANISM(S): Homo sapiens

2010-05-17 | E-GEOD-15402 | biostudies-arrayexpress

Transcription profiling of human lymphoblastoid cells from control males without autism

gene expression profiles of lymphoblastoid cells from individuals with autism and full mutation of FMR1 Experiment Overall Design: Cy5; each individual with autism and FMR1FM Experiment Overall Design: Cy3; pool of 14 unrelated individuals.

ORGANISM(S): Homo sapiens

2008-06-15 | E-GEOD-7316 | biostudies-arrayexpress

Global methylation profiling of lymphoblastoid cell lines reveals epigenetic contributions to autism spectrum disorders

Autism is currently considered a multigene disorder with epigenetic influences. To investigate the contribution of DNA methylation to autism spectrum disorders, we have recently completed large-scale methylation profiling by CpG island microarray analysis of lymphoblastoid cell lines (LCL) derived ...

ORGANISM(S): Homo sapiens

2010-04-27 | E-GEOD-21395 | biostudies-arrayexpress

Transcription profiling of human lymphoblastoid cells from control males without autism

gene expression profiles of lymphoblastoid cells from control males without autism Experiment Overall Design: Cy5; each control male Experiment Overall Design: Cy3; pool of 14 unrelated individuals.

ORGANISM(S): Homo sapiens

2008-06-15 | E-GEOD-7317 | biostudies-arrayexpress

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