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ProteomicsProgressive axonopathy when oligodendrocytes lack the myelin protein CMTM5
Chemokine-like factor-like MARVEL-transmembrane domain containing protein 5 (CMTM5) is a tetraspan-transmembrane protein highly enriched in oligodendrocytes and central nervous system (CNS) myelin. We analyzed the proteome of myelin biochemically purified from mouse brains upon genetic disruption of...
ORGANISM(S): Mus musculus (Mouse) 
2022-04-04 | PXD029443 | Pride
Chemokine-like factor-like marvel-transmembrane domain containing protein (cmtm) family Oligodendrocyte Label-free proteomics Mass spectrometry Central nervous system (cns) Wallerian degeneration Neurodegeneration Myelin proteome 
GenomicsAxonopathy precedes cell death in ocular damage mediated by blast exposure
Axonopathy precedes cell death in ocular damage mediated by blast exposure
PRJNA1148067 | ENA
UnknownProgressive axonopathy when oligodendrocytes lack the myelin protein CMTM5.
Not available
S-EPMC8916772 | biostudies-literature
UnknownEarly axonopathy preceding neurofibrillary tangles in mutant tau transgenic mice.
Not available
S-EPMC1959508 | biostudies-literature
UnknownA novel frameshift variant in ALS2 associated with segmental axonopathy in Merino sheep.
Not available
S-EPMC12551161 | biostudies-literature
UnknownInterleukin-6 Deficiency Attenuates Retinal Ganglion Cell Axonopathy and Glaucoma-Related Vision Loss.
Not available
S-EPMC5450377 | biostudies-literature
TranscriptomicsX-linked adrenoleukosdystrophy disease X-ALD
X-linked adrenoleukodystrophy (X-ALD) is a metabolic genetic disorder of the central nervous system characterized by axonopathy in spinal cords, progressive demyelination in the brain and adrenal insufficiency. Here we provide transcriptomic data from white matter of human X-ALD patients compared to...
ORGANISM(S): Homo sapiens 
2012-03-21 | E-MEXP-3288 | biostudies-arrayexpress
UnknownSarm1 Deletion, but Not WldS, Confers Lifelong Rescue in a Mouse Model of Severe Axonopathy.
Not available
S-EPMC5640801 | biostudies-literature
TranscriptomicsAxonopathy precedes cell death in ocular damage mediated by blast exposure
Traumatic brain injuries (TBI) of varied types are common across all populations and can cause visual problems. For military personnel in combat settings, injuries from blast exposures (bTBI) are prevalent and arise from a myriad of different situations. To model these diverse conditions, we are one...
ORGANISM(S): Mus musculus 
2024-08-14 | GSE274793 | GEO
UnknownAxonopathy is a compounding factor in the pathogenesis of Krabbe disease.
Not available
S-EPMC3690521 | biostudies-literature
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