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MetabolomicsGREM1 Deficiency induced Bone Marrow Adipose Niche promotes B-cell Acute Lymphoblastic Leukemia Disease Progression
Relapse and disease progression are the primary causes of treatment failure and subsequent mortality in children B-cell acute lymphocytic leukemia (B-ALL). At diagnosis and during treatment, the bone marrow adipose microenvironment is commonly observed in pediatric leukemia. However, the relationshi...
2024-09-23 | MTBLS10103 | MetaboLights
MetabolomicsInhibiting glutaminase exerts opposite effects on ovariectomy-induced and age-related reductions in murine bone mass
Recent studies have provided links between glutamine metabolism and bone remodeling, but little is known about its role in primary osteoporosis progression. We aimed to determine the effects of inhibiting glutaminase (GLS) on two types of primary osteoporosis and elucidate the related metabolism. To...
2024-06-17 | MTBLS9415 | MetaboLights
MetabolomicsBone Marrow Metabolomics (part II)
Not available
ORGANISM(S): Mus musculus 
ST000201 | MetabolomicsWorkbench
MetabolomicsBone Marrow Metabolomics (part I)
Not available
ORGANISM(S): Mus musculus 
ST000182 | MetabolomicsWorkbench
MetabolomicsUntargeted metabolites of supernatant of wild-type and Nlrp3-/- bone marrow-derived macrophages with or without LPS and ATP costimulation
Untargeted metabolites of supernatant of wild-type and Nlrp3-/- bone marrow-derived macrophages without stimulation or with 4 hours of LPS preconditioning and subsequently 30 min of ATP stimulation.
2025-07-08 | MTBLS12152 | MetaboLights
MetabolomicsMetabolites in peritoneal macrophages and bone marrow derived macrophages
Not available
ORGANISM(S): Mus musculus 
ST000339 | MetabolomicsWorkbench
MetabolomicsMouse macrophages from bone marrow treatment
Not available
ORGANISM(S): Mus musculus 
ST000174 | MetabolomicsWorkbench
MetabolomicsComparative non-targeted LC-MS metabolomic profiling of murine bone marrow-derived macrophages cultured in 2D versus 3D

Macrophages are key drivers of inflammatory and fibrotic diseases and their activation is shaped by interactions in their tissue microenvironment. However, dissecting the processes that drive immunopathology has proved challenging as traditional 2D culture methods fail to capture the complex mole...

2026-06-08 | MTBLS12917 | MetaboLights
MetabolomicsMetabolomic analysis of normal and diabetic mouse bone marrow under PBS or metformin treatment
Not available
ORGANISM(S): Mus musculus 
ST000164 | MetabolomicsWorkbench
MetabolomicsMetabolomics of bone marrow-derived dendritic cells conditioned with H. polygyrus bakery non-polar metabolites
Not available
ORGANISM(S): Mus musculus 
ST002230 | MetabolomicsWorkbench
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