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TranscriptomicsEstrogen-modulated gene expression in c-kit+ stem cells and CD44+ stromal cells
The recent interest in the role of bone marrow derived endothelial progenitor cells in the benefits of estrogen on cardiovascular health brought us to evaluate if estrogen could affect cardiac repair more broadly by regulating biological processes involved in the functional organization of the bone ...
ORGANISM(S): Mus musculus 
2008-12-10 | E-GEOD-9098 | biostudies-arrayexpress
TranscriptomicsActivating c-KIT mutations confers oncogenic cooperativity and rescue RUNX1-ETO induced DNA-damage in human cells
REtr causes genomic instability in U937 cells. Activated forms of c-KIT, like c-KIT(N822K), rescues the Retr induced genomic instability by increasing the rate of DNA repair by homologous recombination Human U937 cells were transduced with retroviral vectors encoding REtr or c-KIT(N822K), expanded i...
ORGANISM(S): Homo sapiens 
2014-07-29 | E-GEOD-57658 | biostudies-arrayexpress
TranscriptomicsTranscription profile of CD103- vs CD103+ dendritic cells derived from CX3CR1+c-kit+- bone marrow cells (M1993 M2067)
We hypothesize that under homeostatic as well as inflammatory conditions circulating monocytes and/or their bone marrow-derived progenitors might contribute to the replenishment of CD103+ and CD103- DC in lymphoid and non-lymphoid compartments. To that end, bone marrow cells from CX3CR1+/gfp C57BL/6...
ORGANISM(S): Mus musculus 
2008-12-17 | E-GEOD-10882 | biostudies-arrayexpress
GenomicsmRNA profiles of CD43++c-kit+, CD43+c-kit- and CD43-c-Kit- AML1-ETO9a murine leukemic bone marrow cells
mRNA profiles of CD43++c-kit+, CD43+c-kit- and CD43-c-Kit- AML1-ETO9a murine leukemic bone marrow cells
PRJNA772178 | ENA
TranscriptomicsExpression data from small intestinal Lin-c-Kit+Sca-1- cells and Lin-c-Kit-Sca-1- cells.
Small intestinal innate lymphoid cells (ILCs) are known to regulate intestinal epithelial cell homeostasis and to help prevent pathogenic bacterial infections, by producing IL-22. However, other functions of these cells and the lineal relationship between ILCs and lymphoid or myeloid cells have not ...
ORGANISM(S): Mus musculus 
2012-09-15 | E-GEOD-40882 | biostudies-arrayexpress
GenomicsTranscriptome of c-kit+ cells in rat under stress
Transcriptome of c-kit+ cells in rat under stress
PRJNA506367 | ENA
Transcriptomics4C-seq analysis of the c-Kit locus
We characterize the transcriptional loop from c-Kit promoter and a novel c-Kit enhancer 10 millions of cells were use to generate replicate libraries
ORGANISM(S): Mus musculus 
2016-08-25 | E-GEOD-76054 | biostudies-arrayexpress
TranscriptomicsActivating c-KIT mutations confer oncogenic cooperativity and rescue RUNX1-ETO-induced DNA damage in human cells
REtr causes genomic instability in human CD34+ cells. Activated forms of c-KIT, like c-KIT(N822K), rescue the REtr-induced genomic instability by increasing the rate of DNA repair by homologous recombination. Human CD34+ hematopoietic progenitor cells were transduced with retroviral vectors encoding...
ORGANISM(S): Homo sapiens 
2014-09-30 | E-GEOD-58041 | biostudies-arrayexpress
TranscriptomicsmRNA profiles of CD43++c-kit+, CD43+c-kit- and CD43-c-Kit- AML1-ETO9a murine leukemic bone marrow cells
We discovered a spontaneous differentiation path characterized by CD43 and c-Kit in the AE9a murine model, where the leukemia-initiating potential is lost while leukemic cells display features of erythroid maturation. Therefore, we sorted out CD43++c-Kit+, CD43+c-Kit- and CD43-c-Kit- AE9a leukemic c...
ORGANISM(S): Mus musculus 
2022-10-03 | GSE186040 | GEO
TranscriptomicsMicroarray analysis to identify novel genes regulated by Cholera toxin in bone marrow-derived dendritic cells (BMDCs)
The mechanisms by which dendritic cells (DCs) induce differentiation of naïve CD4+ T cells along the Th2 lineage is not well understood given that DCs themselves do not produce IL-4. In the present study, we undertook a microarray approach to identify genes involved in the induction of Th2 differe...
ORGANISM(S): Mus musculus 
2008-04-14 | E-GEOD-10815 | biostudies-arrayexpress
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