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ProteomicsSuccinyl-proteome profiling reveals HDAC8-mediated CAPZB desuccinylation regulates cytoskeleton remodeling in bleomycin-induced idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disease of unknown etiology, characterized by progressive scarring and fibrosis of the lungs, leading to irreversible loss of lung function. Current mechanism studies have found that fibroblasts, as the main effector cells, exhibit ab...
ORGANISM(S): Mus musculus (Mouse) 
2026-04-30 | PXD075455 | Pride
Idiopathic pulmonary fibrosis  lysine succinylation  succinyl-proteome  capzb  hdac8  cytoskeleton remodeling  lc-ms/ms  mouse lung tissue 
UnknownActin capping protein CAPZB regulates cell morphology, differentiation, and neural crest migration in craniofacial morphogenesis†.
Not available
S-EPMC4787901 | biostudies-literature
UnknownExpression of F-actin-capping protein subunit beta, CAPZB, is associated with cell growth and motility in epithelioid sarcoma.
Not available
S-EPMC4787035 | biostudies-literature
TranscriptomicsQuaking is a global regulator of muscle-specific alternative splicing in vertebrates [differentiation data]
This work provides the first evidence that Qk is a global regulator of splicing in vertebrates, defines a new splicing regulatory network in muscle, and suggests that overlapping splicing networks contribute to the complexity of changes in alternative splicing during differentiation. Alternative spl...
ORGANISM(S): Mus musculus 
2013-06-05 | E-GEOD-40956 | biostudies-arrayexpress
TranscriptomicsQuaking is a global regulator of muscle-specific alternative splicing in vertebrates [siRNA data]
This work provides the first evidence that Qk is a global regulator of splicing in vertebrates, defines a new splicing regulatory network in muscle, and suggests that overlapping splicing networks contribute to the complexity of changes in alternative splicing during differentiation. Alternative spl...
ORGANISM(S): Mus musculus 
2013-06-05 | E-GEOD-40961 | biostudies-arrayexpress
UnknownAssociation between rs12045440 Polymorphism in the CAPZB Intron and Serum TSH Concentrations in Chinese Thyroid Tumor Patients.
Not available
S-EPMC4529963 | biostudies-literature
TranscriptomicsF-actin dynamics regulates mammalian organ growth and cell fate maintenance
Cell function depends on the mechanical properties of the microenvironment. Cells probe these features by applying and transmitting forces to their surroundings, via their actomyosin cytoskeleton and adhesion complexes, and then transducing them into biochemical signals. Among these, the transcripti...
ORGANISM(S): Mus musculus 
2019-03-19 | GSE116993 | GEO
TranscriptomicsQuaking is a global regulator of muscle-specific alternative splicing in vertebrates [siRNA data]
This work provides the first evidence that Qk is a global regulator of splicing in vertebrates, defines a new splicing regulatory network in muscle, and suggests that overlapping splicing networks contribute to the complexity of changes in alternative splicing during differentiation. Alternative spl...
ORGANISM(S): Mus musculus 
2013-06-05 | GSE40961 | GEO
TranscriptomicsQuaking is a global regulator of muscle-specific alternative splicing in vertebrates [differentiation data]
This work provides the first evidence that Qk is a global regulator of splicing in vertebrates, defines a new splicing regulatory network in muscle, and suggests that overlapping splicing networks contribute to the complexity of changes in alternative splicing during differentiation. Alternative spl...
ORGANISM(S): Mus musculus 
2013-06-05 | GSE40956 | GEO
UnknownHeterodimeric capping protein is required for stereocilia length and width regulation.
Not available
S-EPMC5674897 | biostudies-literature
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