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GenomicsRNAseq carcinogen induced signatures in lung adenocarcinoma cell lines
RNAseq carcinogen induced signatures in lung adenocarcinoma cell lines
PRJNA521051 | ENA
TranscriptomicsSystematic Comparison of Mouse and Human Oral Squamous Cell Carcinoma by Using Functional Transcriptomic Analysis
This study aims to compare the global expression signature of protein coding genes between oral cancers from carcinogen-induced mice and human patients. Combinatorial treatment of 4NQO and arecoline for 8 weeks consistently induced the formation of mouse oral cancer with morphology and pathology res...
ORGANISM(S): Mus musculus 
2015-12-17 | E-GEOD-64271 | biostudies-arrayexpress
UnknownA signature-agnostic test for differences between tumor mutation spectra reveals carcinogen and ancestry effects.
Not available
S-EPMC12139916 | biostudies-literature
TranscriptomicsTranscription profiling by array of human amnion epithelial FL cells treated with the carcinogen BPDE at low concentration
The environmental carcinogen, (±)-anti-benzo[a]pyrene-7,8-diol-9,10-epoxide (BPDE), causes bulky-adduct DNA damages, triggers certain signaling pathways, and elicits gene expression changes. Here, we focused on the temporal gene expression changes induced by a low concentration (0.05 µM) BPDE in hum...
ORGANISM(S): Homo sapiens 
2009-01-14 | E-GEOD-10979 | biostudies-arrayexpress
TranscriptomicsTranscriptomic response to benzo[a]pyrene treatment in HepG2 cells (RNA-Seq)
Whole-genome transcriptome measurements are pivotal for characterizing carcinogenic mechanisms of chemicals and predicting toxic classes, such as genotoxicity, from in vitro and in vivo assays. DNA microarrays have evolved as the gold standard for this purpose. In recent years deep sequencing techno...
ORGANISM(S): Homo sapiens 
2012-11-16 | E-GEOD-36242 | biostudies-arrayexpress
TranscriptomicsTranscriptomic response to benzo[a]pyrene treatment in HepG2 cells (Affymetrix)
Whole-genome transcriptome measurements are pivotal for characterizing carcinogenic mechanisms of chemicals and predicting toxic classes, such as genotoxicity, from in vitro and in vivo assays. DNA microarrays have evolved as the gold standard for this purpose. In recent years deep sequencing techno...
ORGANISM(S): Homo sapiens 
2012-11-16 | E-GEOD-36243 | biostudies-arrayexpress
MetabolomicsGeographic variation of mutagenic exposures in kidney cancer genomes

International differences in the incidence of many cancer types indicate the existence of carcinogen exposures that have not been identified by conventional epidemiology yet potentially make a substantial contribution to cancer burden1. This pertains to clear cell renal cell carcinoma (ccRCC), fo...

2024-03-26 | MTBLS9394 | MetaboLights
TranscriptomicsRNAseq carcinogen induced signatures in lung adenocarcinoma cell lines
FVB, Balb/c, and C57BL/6 mice received the tobacco carcinogens urethane (Sigma Aldrich, U2500) intraperitoneally (1g/Kg in 100 μl phosphate-buffered saline) or diethylnitrosamine (200 mg/kg) (Sigma Aldrich, N0756). Carcinogen induced lung adenocarcinoma murine cell lines generation| Ten months post ...
ORGANISM(S): Homo sapiens Mus musculus 
2022-10-24 | GSE126119 | GEO
TranscriptomicsGenomic landscape of carcinogen induced mouse skin squamous cell carcinoma: whole-genome sequencing
Low coverage whole-genome sequencing of induced murine squamous cell carcinoma. 17 samples are included.
ORGANISM(S): Mus musculus 
2015-04-10 | E-MTAB-2888 | biostudies-arrayexpress
TranscriptomicsGenomic landscape of carcinogen induced mouse skin squamous cell carcinoma: RNA-sequencing
RNA-sequencing of induced murine squamous cell carcinoma.
ORGANISM(S): Mus musculus 
2015-04-16 | E-MTAB-2889 | biostudies-arrayexpress
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