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TranscriptomicsMicrovascular endothelial heterogeneity
The goal of this study was to gain insight into the molecular heterogeneity of capillary endothelial cells derived from different organs by microarray profiling of freshly isolated cells and identify transcription factors that may determine the specific gene expression profile of endothelial cells f...
ORGANISM(S): Mus musculus 
2015-02-19 | E-GEOD-48209 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of human brain microvascular endothelial cells response to Neisseria meningitidis and its antigen MafA using RNA-seq
Using RNA sequencing to map differentially expressed genes in human brain microvascular endothelial cells challenged with Neisseria meningitidis or its ligand MafA .
ORGANISM(S): Homo sapiens 
2019-06-15 | E-MTAB-8008 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat aortic and endocardial endothelial cells
Endocardial (EE) and Aortic (AE) endothelial cells were isolated from the same two rats, pooled (EE and AE kept separately) and cultured for 2 passages. Culture conditions and confluence of EE and AE cell cultures were kept as identical as possible. RNA was isolated and the expression profile of bot...
ORGANISM(S): Rattus norvegicus 
2008-06-11 | E-GEOD-1478 | biostudies-arrayexpress
TranscriptomicsRNA expression profiling in primary and immortalized human mesothelial cells, and in human vein and microvascular endothelial cells
Mesothelial cells, which interact with endothelial cells, are widely used in research including cancer and drug development, have not been comprehensively profiled. We therefore performed RNA sequencing of polarized, primary peritoneal (HPMC) and immortalized pleural mesothelial cells (MeT-5A), and ...
ORGANISM(S): Homo sapiens 
2023-05-24 | E-MTAB-12021 | biostudies-arrayexpress
ProteomicsSleep fragmentation exacerbates cardiac microvascular endothelial cell cuproptosis via promoting neutrophil extracellular trap formation in myocardial ischemia-reperfusion injury
Objective: This study aimed to investigate the relationship between sleep disorders and cardiac microvascular injury in myocardial ischemia-reperfusion injury (MI/RI) mice. Design: Mice were placed in a sleep deprivation chamber. The sweep bar moved along the bottom of the cage every 2 min during th...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-08 | PXD066510 | Pride
Myocardial ischemia-reperfusion injury  sleep fragmentation  neutrophil extracellular traps  cardiac microvascular endothelial cells  cuproptosis 
TranscriptomicsLoss of endothelial miR-143/145 accelerates vascular senescence and diastolic cardiac dysfunction
Age‑associated vascular remodelling critically contributes to cardiac dysfunction, yet the molecular drivers of cardiac vascular senescence remain incompletely understood. Here, we describe a novel function of the miR-143/145 cluster in cardiac endothelial cells. Global deletion of miR‑143/145 in mi...
ORGANISM(S): Homo sapiens 
2026-10-09 | E-MTAB-17783 | biostudies-arrayexpress
ProteomicsMice CMECs TMT-based quantitative proteomic
Glucagon signaling blockade protects cardiac microvascular endothelial cells by inhibiting fatty acid β-oxidation and mitochondrial fusion
ORGANISM(S): Mus Musculus 
2021-08-12 | PXD027916 |
TranscriptomicsGlobal gene expression profiling of endothelial cells from different vascular bed and caliber
Endothelial cells (EC) were obtained from commercial source (Lonza), expanded and culture until passage 3. HMVEC-LBI correspond to lung microvascular endothelial cells, HPAEC to lung macrovascular endothelial cells, HAEC to cardiac macrovascular endothelial cells and HMVEC-C to cardia microvascular ...
ORGANISM(S): Homo sapiens 
2023-01-30 | E-MTAB-4886 | biostudies-arrayexpress
TranscriptomicsComparative Gene Expression Profiling of HUVEC and Ocular Vascular Endothelial Cells
To compare the gene expression profiles of unpassaged, proliferating HUVEC and human iris, retinal and choroidal microvascular endothelial cells. Gene expression profiling revealed significant differences between HUVEC and ocular microvascular endothelial cells suggesting that HUVE cells may not be ...
ORGANISM(S): Homo sapiens 
2010-12-31 | E-GEOD-20986 | biostudies-arrayexpress
GenomicsComparison of cellular transcriptome between mouse cardiac microvascular cell types.
Comparison of cellular transcriptome between mouse cardiac microvascular cell types.
PRJNA788501 | ENA
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