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TranscriptomicsExpression data comparing Hep3B Caveolin-1 (Cav1) knockdown cells with Hep3B non-target control cells
To identify genes regulated by Cav1 Affymetrix Human Genome U133 Plus 2.0 GeneChip Hep3B cells with or without knockdown of Cav1
ORGANISM(S): Homo sapiens 
2016-03-01 | E-GEOD-75994 | biostudies-arrayexpress
GenomicsExpression data from cav1-/+apcmin/+ mouse intestinal tissue
Expression data from cav1-/+apcmin/+ mouse intestinal tissue
PRJNA513965 | ENA
TranscriptomicsImpact of CAV1 target site blocker (CAV1 TSB) on bleomycin-induced lung fibrosis
To assess whether CAV1 represents the main target associated with miR-199a-5p profibrotic activity, we designed a CAV1 target site blocker (TBS) to specifically disrupt miR-199a-5p interaction with mCAV1 3’UTR. CAV1 TSB (5mg/kg) or control formulated for in vivo delivery (Control TSB) was instilled ...
ORGANISM(S): Mus musculus 
2019-04-11 | GSE97826 | GEO
TranscriptomicsImpact of miR-199-5p overexpression and CAV1 silencing on human lung fibroblasts
To identify putative novel specific targets of mir-199-5p, we overexpressed miR-199a-5p as well as miR-21 and a siRNA targeted against CAV1 in human HFL1 pulmonary fibroblasts (CCL-153) by transfecting them with synthetic pre-miRNAs or a synthetic “negative” pre-miRNA as control (miR-Neg). RNA sam...
ORGANISM(S): Homo sapiens 
2013-02-01 | E-GEOD-34815 | biostudies-arrayexpress
ProteomicsNeuroretinal-derived caveolin-1 promotes endotoxin-induced inflammation in the murine retina
Chronic ocular inflammation is associated with many retinal degenerative diseases that result in vision loss. The immune-privileged environment and complex organization of retinal tissue allow for the retina’s essential role in visual function processes, yet confound inquiries into cell-specific inf...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-08 | PXD016872 | Pride
Caveolin-1  caveolin  caveolae  inflammation  neural retina  retina  retinal degeneration  immune response 
TranscriptomicsSingle epicardial cell transcriptome sequencing identifies Caveolin-1 as an essential factor in zebrafish heart regeneration
By contrast with mammals, adult zebrafish have a high capacity to regenerate damaged or lost myocardium through proliferation of spared cardiomyocytes. The epicardial sheet covering the heart is activated by injury and aids muscle regeneration through paracrine effects and as a multipotent cell sou...
ORGANISM(S): Danio rerio 
2015-12-15 | E-GEOD-75583 | biostudies-arrayexpress
UnknownCaveolin-1 is ubiquitinated and targeted to intralumenal vesicles in endolysosomes for degradation
Not available
S-JCBD-201003086 | bioimages
GenomicsMus musculus
Impact of CAV1 target site blocker (CAV1 TSB) on bleomycin-induced lung fibrosis
PRJNA382977 | ENA
Genomics
CAV1 knockdown in MM1S cells
PRJNA1028364 | ENA
TranscriptomicsExpression data from cav1-/+apcmin/+ mouse intestinal tissue
We used microarrays to decipher the global programme of gene expression in normal colon tissue versus colorectal tumor tissue explants from 6 months old cav1-/+ apcmin/+ mice and identified distinct classes of differentially regulated genes.
ORGANISM(S): Mus musculus 
2019-01-10 | GSE124838 | GEO
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