Caveolin-1 - OmicsDI

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UNIPROT ID/AC

A0A024R563 (1)
A0A024R8H9 (1)
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A0A087WUD1 (1)
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ENSEMBL ID

ENSG00000147251 (1)
ENSG00000170477 (1)
ENSG00000247315 (1)

CHEBI ID

CHEBI:174822 (2)
CHEBI:18414 (2)
CHEBI:15889 (2)
CHEBI:138533 (2)
CHEBI:73920 (2)
CHEBI:174200 (2)
CHEBI:166762 (2)
CHEBI:74349 (2)
CHEBI:76451 (2)
CHEBI:36790 (2)
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CHEBI:12936 (2)
CHEBI:17364 (2)
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CHEBI:17808 (2)
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CHEBI:17609 (2)
CHEBI:29507 (2)
CHEBI:34671 (2)
CHEBI:34146 (2)
CHEBI:28209 (2)
CHEBI:139582 (2)
CHEBI:170015 (2)
CHEBI:165449 (2)
CHEBI:16964 (2)
CHEBI:17285 (2)
CHEBI:46905 (2)
CHEBI:133185 (2)
CHEBI:36108 (2)

Metabolite Name

PI(39:6) (1)
PS(36:0) (1)
PI(35:1) (1)
PS(33:1) (1)
5-HYDROXY-L-TRYPTOPHAN (1)
N-METHYL-L-GLUTAMATE (1)
O-ACETYL-L-CARNITINE (1)
2'-DEOXYCYTIDINE 5'-DIPHOSPHATE (1)
Hydroxyphenanthrene (1)
THIAMINE MONOPHOSPHATE (1)
D-ASPARTATE (1)
PHOSPHONOACETATE (1)
5.6-DIHYDROURACIL (1)
PIPECOLATE (1)
3-AMINO-4-HYDROXYBENZOIC ACID (1)
Lysophosphatidylcholine(17:0) (1)
Lysophosphatidylethanolamine(22:6) (1)
3-HYDROXYKYNURENINE (1)
5-methoxy-3-indoleacetic acid (1)
Lysophosphatidylcholine(18:0) (1)
D-ORNITHINE (1)
S-(5'-ADENOSYL)-L-HOMOCYSTEINE (1)
URIDINE 5'-DIPHOSPHATE_In source of UDP-glucuronic acid (1)
PICOLINIC ACID (1)
Lysophosphatidylcholine(22:6) (1)
15(s)-HETE (1)
12(s)-HETE (1)
5(s)-HETE (1)
S-(5'-Adenosyl)-L-Methionine (1)
INOSINE 5'-DIPHOSPHATE (1)

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Study type

Transcription profiling by array (30)
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Release Date

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Lab affiliation

School of Optometry, The Hong Kong Polytechnic University (2)
1Center for Cardiovascular Regeneration, Department of Cardiovascular Sciences, Houston Methodist Research Institute. Houston Methodist, 6550 Fannin Street, Texas 77030, USA. (1)
Biochemistry and Molecular Biology, The Institute for Medical Research Israel-Canada (IMRIC). School of Medicine. The Hebrew University of Jerusalem, Israel. (1)
Department of Biochemistry and Molecular Biology, University of Southern Denmark (1)
Department of Biophysics All India Institute of Medical Sciences New Delhi 110029 India (1)
Department of Chemistry, University of Illinois Chicago, Chicago, USA (1)
Department of Microbiology and Immunology, Eulji University School of Medicine,Daejeon, South Korea (1)
Department of Redox Molecular Medicine, Tohoku University Graduate School of Medicine (1)
ETH Zürich (1)
Group Leader Protein Dynamics ISAS e.V. Otto-Hahn-Straße 6b 44227 Dortmund, Germany (1)
Group Leader, Primate Biology, National Institute for Research in Reproductive Health, India (1)
Helmholtz Zentrum München, Neuherberg, Germany (1)
Institute of Integrative Biology Biosciences Building Crown Street University of Liverpool Liverpool L69 7ZB UK (1)
Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France; University of Paris, Imagine Institute, Paris, France; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA; Department of Pediatrics, Necker Hospital for Sick Children, AP-HP, Paris, France; Howard Hughes Medical Institute, New York, NY, USA (1)
Luxembourg Institute of Health 1A-B, rue Thomas Edison, L-1445 Strassen Luxembourg (1)
Research Unit Adipocytes & Metabolism (ADM), Helmholtz Diabetes Center, Helmholtz Zentrum München, German Research Center for Environmental Health GmbH, 85764, Neuherberg, Germany (1)
Shanghai Institute of Materia Medica, Chinese Academy of Sciences (1)
The University of Queensland, Institute for Molecular Bioscience, Division of Cell Biology and Molecular Medicine, Building 80, Services Rd, St Lucia, Brisbane, Queensland 4072, Australia (1)
The University of Queensland, Institute for Molecular Bioscience, 4072, Brisbane, Australia; The University of Queensland, Centre for Microscopy and Microanalysis, 4072, Brisbane, Australia (1)
The University of Texas MD Anderson Cancer Center (1)
Tianjin Medical University Eye Hospital, Tianjin Medical University Ophthalmology Research Institute，Tianjin,300384 (1)
University of Eastern Piedmont Department of Sciences and Technological Innovation, University of Piemonte Orientale, Italy (1)

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Seipin Governs Caveolin-1 Trafficking Through Modulating Sphingolipid-Glycerolipid Balance

Dysregulation of Caveolin-1 (CAV1), a key component of caveolae, leads to pleiotropic disorders; yet, the mechanisms controlling its trafficking remain unclear. Here, we show that the lipid droplet (LD) biogenesis factor seipin controls CAV1 localization. Seipin deficiency in mice and HeLa cells ...

2025-07-22 | MTBLS12759 | MetaboLights

ECM deposition is driven by caveolin1-dependent regulation of exosomal biogenesis and cargo sorting

The composition and physical properties of the extracellular matrix (ECM) critically influence tumor progression, but the molecular mechanisms underlying ECM layering are poorly understood. Tumor-stroma interaction is critically dependent on cell-cell communication mediated by exosomes, small ves...

2020-10-07 | MTBLS1977 | MetaboLights

ECM deposition is driven by caveolin1-dependent regulation of exosomal biogenesis and cargo sorting

2020-10-07 | MTBLS1969 | MetaboLights

Transcription profiling by array of human HT29 colon cancer cells to investigate the role of Caveolin 1, E-Cadherin, Enolase 2 and PKCa on resistance to methotrexate

A summary of the work associated to these microarrays is the following:; Methotrexate (MTX) is one of the earliest cytotoxic drugs used in cancer therapy, and despite the isolation of multiple other folate antagonists, methotrexate maintains its significant role as a treatment for different types of...

ORGANISM(S): Homo sapiens

2008-10-25 | E-GEOD-11440 | biostudies-arrayexpress

Transcription profiliing of mouse caveolin-1 knockout hearts

Hearts Lacking Caveolin-1 Develop Hypertrophy with Normal Cardiac Substrate Metabolism Experiment Overall Design: 3 wild types, 3 knockouts

ORGANISM(S): Mus musculus

2009-03-15 | E-GEOD-10849 | biostudies-arrayexpress

LS001A: Aging/Early Degeneration Of The Intervertebral Disc Involves Downregulation Of Canonical Wnt Signaling and Caveolin-1 expression

Objective: Aging and early degeneration of the intervertebral disc (IVD) involves the substition of notochordal cells (NCs) in the nucleus pulposus (NP) by chondrocyte-like cells (CLCs). This study investigated the gene expression profiles involved in this process using NP tissue from both non-chond...

ORGANISM(S): Canis lupus familiaris

2013-01-31 | E-GEOD-35717 | biostudies-arrayexpress

Single epicardial cell transcriptome sequencing identifies Caveolin-1 as an essential factor in zebrafish heart regeneration

By contrast with mammals, adult zebrafish have a high capacity to regenerate damaged or lost myocardium through proliferation of spared cardiomyocytes. The epicardial sheet covering the heart is activated by injury and aids muscle regeneration through paracrine effects and as a multipotent cell sou...

ORGANISM(S): Danio rerio

2015-12-15 | E-GEOD-75583 | biostudies-arrayexpress

Hepatocypte-specific Caveolin-1 knockout livers

PRJNA565232 | ENA

Caveolin-1 knockout liver and gonadal adipose tissue

mRNA expression was compared in between wild type and caveolin-1 knockout livers mRNA expression was compared in between wild type and caveolin-1 knockout gonadal adipose tissue RNA was isolated from livers from male mice in at the light phase RNA was isolated from gonadal adipose tissues from male ...

ORGANISM(S): Mus musculus

2012-01-31 | E-GEOD-35431 | biostudies-arrayexpress

Neuroretinal-derived caveolin-1 promotes endotoxin-induced inflammation in the murine retina

Chronic ocular inflammation is associated with many retinal degenerative diseases that result in vision loss. The immune-privileged environment and complex organization of retinal tissue allow for the retina’s essential role in visual function processes, yet confound inquiries into cell-specific inf...

ORGANISM(S): Mus musculus (Mouse)

2021-09-08 | PXD016872 | Pride

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