Sort   by:  
 Page size 
ProteomicsFunctional characterization of the human Cdk10/Cyclin Q complex
Cyclin-dependent kinases (CDKs) are key players in cell cycle regulation and transcription. The CDK-family member Cdk10 is important for neural development and can act as a tumor suppressor but the underlying molecular mechanisms are largely unknown. Here, we provide an in depth analysis of Cdk10 su...
ORGANISM(S): Escherichia coli 
2022-03-20 | PXD028792 | Pride
Transcription  cell cycle  cdk10  cyclin q  cyclin m  rna polymerase ii 
GenomicsCDK10 suppresses nucleic acid sensors-mediated antitumor immunity [RNA-Seq]
CDK10 suppresses nucleic acid sensors-mediated antitumor immunity [RNA-Seq]
PRJNA1211066 | ENA
GenomicsCDK10 suppression sensitizes cells to CDK12/13 blockade
CDK10 suppression sensitizes cells to CDK12/13 blockade
PRJNA1314771 | ENA
GenomicsCDK10 suppresses nucleic acid sensors-mediated antitumor immunity [scRNA-Seq]
CDK10 suppresses nucleic acid sensors-mediated antitumor immunity [scRNA-Seq]
PRJNA1211064 | ENA
TranscriptomicsCDK10 suppresses nucleic acid sensors-mediated antitumor immunity [RNA-Seq]
Cdk10 knockout significantly reduced CT26 tumor growth in immunocompetent BALB/c WT mice.To elucidate the molecular mechanisms by which Cdk10 suppresses anti-tumor immunity, we conducted transcriptomic analyses on WT and Cdk10 KO CT26 cells
ORGANISM(S): Mus musculus 
2025-10-27 | GSE287054 | GEO
TranscriptomicsCDK10 suppression sensitizes cells to CDK12/13 blockade
A CRISPR screen with a CDK12/13 inhibitor identified CDK10 as a modulator of CDK12/13 blockade. CDK10 KO cells in OVCA and BRCA showed higher sensitivity to CDK12/13 inhibitors and increased apoptosis, compared to wild type cells. To investigate the effects on transcription, CDK10 KO cells with or w...
ORGANISM(S): Homo sapiens 
2026-06-09 | GSE307213 | GEO
TranscriptomicsCDK10 suppresses nucleic acid sensors-mediated antitumor immunity [scRNA-Seq]
Cdk10 knockout significantly reduced CT26 tumor growth in immunocompetent BALB/c WT mice. To investigate how Cdk10 influences the tumor immune microenvironment in vivo, we performed single-cell RNA sequencing (scRNA-seq) on WT and Cdk10 KO CT26 tumors derived from immunocompetent BALB/c mice.
ORGANISM(S): Mus musculus 
2025-10-27 | GSE287052 | GEO
UnknownFunctional characterization of the human Cdk10/Cyclin Q complex.
Not available
S-EPMC8924752 | biostudies-literature
UnknownFunctional characterization of CDK10 and cyclin M truncated variants causing severe developmental disorders.
Not available
S-EPMC8580092 | biostudies-literature
UnknownCDK10 Mutations in Humans and Mice Cause Severe Growth Retardation, Spine Malformations, and Developmental Delays.
Not available
S-EPMC5591019 | biostudies-literature
Sort   by:  
 Page size