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MetabolomicsRole of breast milk lipid composition in postnatal brain development.

Lipids in the brain play a crucial role as structural and signaling molecules, accounting for approximately 60% of the brain’s dry weight. Several lipid classes exhibit concentration profile differences between humans and other species, including closely related primates, with the most pronounced...

2025-09-25 | MTBLS12481 | MetaboLights
ProteomicsInferior Temporal Gyrus in Human Ageing: a Quantitative Protein Profiling Work based on Chinese Human Brain Bank
The temporal lobe is the cerebral cortex with critical function. The superior and middle gyrus of temporal lobe have been well studied, however, present perceptions on inferior temporal gyrus remains limited. The understanding of age-related protein profile change in human inferior temporal gyrus ha...
ORGANISM(S): Homo sapiens (Human) 
2015-12-07 | PXD002528 | Pride
Inferior temporal gyrus  tmt  proteomics  ageing  chinese human brain bank. 
ProteomicsTMT-labeled quantitative protein profiling of hippocampus during human aging
Human hippocampus is one of the critical brain regions affected by aging. However, a fully understanding of aging-related changes in protein profiles in human hippocampus has not been well described, especially for the Chinese population. With the newly founded human brain bank in Chinese Academy of...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-28 | MSV000080710 | MassIVE
ProteomicsProtein Profile Changes in the Frontotemporal Lobes in Human Severe Traumatic Brain Injury
Severe traumatic brain injury (sTBI) is a serious public health issue with high morbidity and mortality rates. Previous proteomic studies on sTBI have mainly focused on human cerebrospinal fluid and serum, as well as on brain protein changes in murine models. However, human proteomic data in sTBI br...
ORGANISM(S): Homo sapiens (Human) 
2016-04-15 | PXD002783 | Pride
Severe traumatic brain injury  tmt (tandem mass tags)  human  proteomics 
TranscriptomicsGene expression data from primate postnatal brain development - superior frontal gyrus
In development, timing is of the utmost importance, and the timing of various developmental processes are often changed during evolution. During human evolution sexual maturation has been delayed relative to other primates and this may have played a critical role for both the increase of human brain...
ORGANISM(S): Homo sapiens 
2009-03-09 | E-GEOD-15163 | biostudies-arrayexpress
TranscriptomicsWidespread splicing changes in human brain development and aging
Differences in transcript splicing are well documented among tissues and between sexes in humans and other organisms. Further, splicing changes in selected genes have been reported in human and mouse brain development. Using high-throughput RNA sequencing we characterized the transcriptome-wide spli...
ORGANISM(S): Homo sapiens 
2013-01-22 | E-GEOD-26586 | biostudies-arrayexpress
TranscriptomicsMicroRNA expression in primate postnatal brain through lifespan
While multiple studies have reported the accelerated evolution of brain gene expression in the human lineage, the mechanisms underlying such change remain poorly understood. Here we address this issue from a developmental perspective, by analyzing mRNA and microRNA (miRNA) expression in two brain re...
ORGANISM(S): Pan troglodytes 
2011-12-09 | E-GEOD-29356 | biostudies-arrayexpress
TranscriptomicsMicroRNA expression and regulation in human, chimpanzee, and macaque brain
Among other factors, changes in gene expression on the human evolutionary lineage have been suggested to play an important role in the establishment of human-specific phenotypes. However, the molecular mechanisms underlying these expression changes are largely unknown. Here, we have explored the rol...
ORGANISM(S): Homo sapiens 
2011-10-17 | E-GEOD-26545 | biostudies-arrayexpress
ProteomicsTMT-labeled quantitative protein profiling of hippocampus during human aging
Human hippocampus is one of the critical brain regions affected by aging. However, a fully understanding of aging-related changes in protein profiles in human hippocampus has not been well described, especially for the Chinese population. With the newly founded human brain bank in Chinese Academy of...
ORGANISM(S): Homo sapiens (Human) 
2016-04-13 | PXD001987 | Pride
Human Aging Hippocampus 
UnknownChinese Color Nest Project : An accelerated longitudinal brain-mind cohort.
Not available
S-EPMC8517840 | biostudies-literature
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