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TranscriptomicsGene expression in the mitochondrial syndrome of coenzyme Q deficiency
Coenzyme Q10 deficiency syndrome includes a clinically heterogeneous group of mitochondrial diseases characterized by low content of CoQ10 in tissues. The only currently available treatment is supplementation with CoQ10, which improves the clinical phenotype in some patients but does not reverse est...
ORGANISM(S): Homo sapiens 
2013-04-05 | E-GEOD-33940 | biostudies-arrayexpress
TranscriptomicsCoenzyme Q10-dependent gene expression in SAMP1 mice tissues
Our present study reveals significant decelerating effects on senescence processes in middle-aged SAMP1 mice supplemented for 6 or 14 months with the reduced form (QH2, 500 mg/ kg BW/ day) of coenzyme Q10 (CoQ10). To unravel molecular mechanisms of these CoQ10 effects, a genome-wide transcript profi...
ORGANISM(S): Mus musculus 
2010-03-15 | E-GEOD-15129 | biostudies-arrayexpress
TranscriptomicsCommon gene expression profile in the mitochondrial syndrome of coenzyme Q deficiency
Coenzyme Q10 deficiency syndrome includes a clinically heterogeneous group of mitochondrial diseases characterized by low content of CoQ10 in tissues. The only currently available treatment is supplementation with CoQ10, which improves the clinical phenotype in some patients but does not reverse est...
ORGANISM(S): Homo sapiens 
2013-04-05 | E-GEOD-33769 | biostudies-arrayexpress
MetabolomicsThermal Profiling Maps Multilayered Organization of the Mitochondrial Proteome

Mitochondria execute essential metabolic, biosynthetic, and signaling functions, yet the regulatory principles governing their proteome remain incompletely understood. Here, we develop a thermal proteome profiling (TPP) workflow applied directly to purified mitochondria, enabling systematic analy...

2025-12-08 | MTBLS7386 | MetaboLights
TranscriptomicsCoenzyme Q10-dependent gene expression in SAMP1 mice tissues
Our present study reveals significant decelerating effects on senescence processes in middle-aged SAMP1 mice supplemented for 6 or 14 months with the reduced form (QH2, 500 mg/ kg BW/ day) of coenzyme Q10 (CoQ10). To unravel molecular mechanisms of these CoQ10 effects, a genome-wide transcript profi...
ORGANISM(S): Mus musculus 
2010-03-05 | GSE15129 | GEO
UnknownAssociation between coenzyme Q10 and glucose transporter (GLUT1) deficiency.
Not available
S-EPMC4228097 | biostudies-literature
TranscriptomicsIdentification of LPS-inducible genes down-regulated by ubiquinone in human THP-1 cells
Coenzyme Q10 (CoQ10) is an obligatory element in the respiratory chain and functions as a potent antioxidant of lipid membranes. More recently, anti-inflammatory effects as well as an impact of CoQ10 on gene expression have been observed. To reveal putative effects of Q10 on LPS-induced gene express...
ORGANISM(S): Homo sapiens 
2010-12-22 | E-GEOD-19625 | biostudies-arrayexpress
UnknownIntrastriatal administration of coenzyme Q10 enhances neuroprotection in a Parkinson's disease rat model.
Not available
S-EPMC7293316 | biostudies-literature
UnknownCoenzyme Q10 and Oxidative Stress: Inflammation Status in Hepatocellular Carcinoma Patients after Surgery.
Not available
S-EPMC5295073 | biostudies-literature
UnknownCoenzyme Q10 and Dementia: A Systematic Review.
Not available
S-EPMC9952341 | biostudies-literature
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