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ProteomicsLL10000 hybridization
The screening of a previously reported fluorescein labelled 10,000 member PNA encoded peptide library allowed information on the interaction between the peptide-ligands and the cell surface receptors to be extracted, identified new peptide ligands for cell surface receptors, and gave crucial informa...
ORGANISM(S): Homo sapiens 
2011-11-08 | E-MEXP-3104 | biostudies-arrayexpress
ProteomicsCell array 10000 hybridization
The incubation of a 10,000 member PNA-encoded peptide library with cells over-expressing the alpha(v)beta(3) and alpha(v)beta(5) integrins (D54) or CCR6 (HEK293T-CCR6) followed by microarray analysis allowed detailed information on the interaction between peptide-ligands and cell surface receptors t...
ORGANISM(S): Homo sapiens 
2011-08-10 | E-MEXP-3103 | biostudies-arrayexpress
ProteomicsSynthetic (Phospho)Peptide Library
The submitted dataset contains raw files from 96 synthetic peptide libraries, using either HCD or ETD as fragmentation technique. The synthesized 96 tryptic peptide libraries containing >100,000 unmodified peptides plus their corresponding >100,000 phosphorylated counterparts with precisely known s...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-04-14 | MSV000091718 | MassIVE
TranscriptomicsDNA_library hybridization
PCR read-off microarrays: The ability to efficiently and economically generate libraries of defined pieces of DNA would have a myriad of applications, not least in the area of defined or directed sequencing and synthetic biology, such as protein engineering and aptamer library screening, but also in...
ORGANISM(S): Homo sapiens 
2011-11-08 | E-MEXP-3099 | biostudies-arrayexpress
UnknownOn-bead screening of combinatorial libraries: reduction of nonspecific binding by decreasing surface ligand density.
Not available
S-EPMC2765537 | biostudies-literature
TranscriptomicsRNA sequencing of HEK293T cells expressing peptide 9J10, a 14-3-3 interacting peptide
We investigated the transcriptome profile of HEK293T cells transfected with a plasmid encoding 9J10, a peptide isolated in a phenotypic screen from a library of peptides derived from bacterial and archaeal genomes. The peptide was identified in a screen for FOXO3a reactivation and has been shown to...
ORGANISM(S): Homo sapiens 
2021-05-28 | E-MTAB-10161 | biostudies-arrayexpress
UnknownEvaluating Translational Efficiency of Noncanonical Amino Acids to Inform the Design of Druglike Peptide Libraries.
Not available
S-EPMC9872084 | biostudies-literature
ProteomicsProteomic tools for the quantitative analysis of artificial peptide libraries: detection and characterization of target-amplified PD-1 inhibitors
We report a quantitative proteomics data analysis pipeline which, coupled to protein-directed dynamic combinatorial chemistry (DDC) experiments, enables the rapid discovery and direct characterization of protein-protein interaction (PPI) modulators. A low-affinity PD-1 binder was incubated with a li...
ORGANISM(S): Homo sapiens (Human) 
2022-04-19 | PXD028412 | Pride
Medicinal chemistry Drug discovery Mass spectrometry 
UnknownTargeting deeper the human serum fucome by a liquid-phase multicolumn platform in combination with combinatorial peptide ligand libraries.
Not available
S-EPMC3959646 | biostudies-literature
UnknownCombinatorial targeting and discovery of ligand-receptors in organelles of mammalian cells.
Not available
S-EPMC3337985 | biostudies-literature
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