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Unknown (55)
Genomics (23)
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Homo sapiens (20)
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Organisms

Rattus norvegicus (7)
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biostudies-arrayexpress (72)
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Tissue

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Technology Type

Mass Spectrometry (2)
Mass spectrometry (1)
Bottom-up proteomics (1)
Data-dependent acquisition (1)
Shotgun proteomics (1)

Instrument Platform

Illumina HiSeq 2000 (2)
Non (1)
MouseWG-6_V2_0_R3_11278593_A (1)
G2565AA DNA microarray scanner [Agilent] (1)
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Metabolite Name

Adefovir Dipivoxil (Preveon, Hepsera) (1)
Indomethacin (Indocid, Indocin) (1)
MLS001148580-01!6ALPHA,9ALPHA-DIFLUOROPREDNISOLONE 21-ACETATE 17-BUTYRATE (1)
Toremifene Citrate (Fareston, Acapodene) (1)
[(1S,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate (1)
(+)-Cycloolivil 4'-O-¦Â-D-glucopyranoside (1)
(+)-Fasciculic acid B (1)
(+)-Lyoniresinol 2¦Á-O-¦Â-D-glucopyranoside (1)
(-)-Medicocarpin;Medicarpin 3-O-glucoside (1)
(-)-Syringaresinol-4-O-¦Â-D-glucopyranoside (1)
(-)-threo-Iso(homo)2-citrate;(-)-threo-1-Hydroxy-1,2,5-pentanetricarboxylic acid;1-Hydroxypentane-1,2,5-tricarboxylate;threo-(Homo)2-isocitrate (1)
(1)Benzopyrano(5,4,3-cde)(1,3)dioxolo(4,5-h)(1)benzopyran-5,11-dione, 1,2,3-trimethoxy- (1)
(1,3-Dihydroxy-6,8a-dimethyl-3-propan-2-yl-1,2,3a,4,5,8-hexahydroazulen-4-yl) 3,4-dimethoxybenzoate (1)
(10-Hydroxy-8,8-dimethyl-2-oxo-9,10-dihydropyrano[2,3-f]chromen-9-yl) (Z)-2-methylbut-2-enoate (1)
(11E)-11-Octadecenoic acid (1R,2S)-2-[[(Z)-9-hexadecenoyl]oxy]-1-methylpropyl ester (1)
(12Z)-9,10,11,14,15,16,17,18,19,20,21,22-Dodecahydro-5,8-ethenobenzo[20]annulene-2,4,6,24-tetrol (1)
(13S)-13-Ethoxy-1,2-dimethoxy-12-methyl-13H-[1,3]benzodioxolo[5,6-c]phenanthridine (1)
(14E)-11-hydroxy-14-(1H-imidazol-5-ylmethylidene)-2-methoxy-9-(2-methylbut-3-en-2-yl)-2,13,16-triazatetracyclo[7.7.0.01,13.03,8]hexadeca-3,5,7-triene-12,15-dione (1)
(14S)-9,20,21,25-Tetramethoxy-15-methyl-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.23,6.18,12.114,18.027,31.022,33]hexatriaconta-1(30),3(36),4,6(35),8,10,12(34),18,20,22(33),24,26,28,31-tetradecaen-2-one (1)
(19E,21E,23E,25E,27E,29E,31E)-17-[7-(4-aminophenyl)-5-hydroxy-4-methyl-7-oxoheptan-2-yl]-1,3,5,33,37-pentahydroxy-18,36-dimethyl-16,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-9,13,15-trione (1)
(19E,21E,23E,25E,27E,29E,31E)-17-[7-(4-aminophenyl)-5-hydroxy-4-methyl-7-oxoheptan-2-yl]-1,3,5,7,33,37-hexahydroxy-18-methyl-9,13,15-trioxo-16,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylate (1)
(1E)-4-hydroxy-1-(4-hydroxy-3-methoxyphenyl)dodec-1-en-3-one (1)
(1E,3Z)-buta-1,3-diene-1,2,4-tricarboxylate (1)
(1R)-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium-7-ol (1)
(1R)-1-[[(2S,3R,11bS)-3-ethyl-9,10-dimethoxy-1,2,3,4,5,6,7,11b-octahydrobenzo[a]quinolizin-5-ium-2-yl]methyl]-7-methoxy-1,2,3,4-tetrahydroisoquinolin-2-ium-6-ol (1)
(1R,10R)-5-amino-14-oxido-14-oxo-13,15,18-trioxa-2,4,6,9-tetraza-14lambda5-phosphatetracyclo[8.8.0.03,8.012,17]octadeca-3(8),4-diene-7,11-dione (1)
(1R,14R,24S)-24-Methoxy-5,7,19,21,25-pentaoxa-13-azahexacyclo[12.11.0.02,10.04,8.015,23.018,22]pentacosa-2,4(8),9,15(23),16,18(22)-hexaene (1)
(1R,2'S,3'aS,12S,14S)-2',12-dimethylspiro[13-oxa-2,10,17-triazatetracyclo[10.3.2.02,11.04,9]heptadeca-4,6,8,10-tetraene-14,4'-3,3a-dihydro-2H-imidazo[1,2-a]indole]-1',3,16-trione (1)
(1R,2R,5R,8R,9S,10R,11S)-11-methyl-6-methylidene-16-oxo-15-oxapentacyclo[9.3.2.15,8.01,10.02,8]heptadecane-9-carboxylate (1)
(1R,2R,5S,8S,9S,10R,11R,12R,13S)-5,12,13-trihydroxy-11-methyl-6-methylidene-16-oxo-15-oxapentacyclo[9.3.2.15,8.01,10.02,8]heptadecane-9-carboxylate (1)

First Public Date

2025 (4)
2026 (2)
2024 (2)
2023 (2)
2018 (2)
2014 (2)
2020 (1)
2019 (1)

Study type

Transcription profiling by array (47)
Unknown experiment type (5)
ChIP-seq (5)
RNA-seq of coding RNA (5)
ChIP-chip by tiling array (3)
Transcription profiling by SAGE (1)
Cell line - One-color microarray (1)
RNAi profiling by array (1)
ChIP-chip by array (1)
Genotyping by array (1)
Methylation profiling by array (1)
RNA-seq of non coding RNA (1)

Release Date

2010 (20)
2015 (16)
2008 (11)
2017 (9)
2025 (7)
2009 (6)
2023 (6)
2022 (6)
2014 (5)
2013 (5)
2012 (5)
2018 (5)
2024 (4)
2021 (4)
2016 (4)
2020 (4)
2019 (4)
2011 (3)
2007 (2)
2004 (1)

Lab affiliation

1. School of Pharmacy and Bioengineering, Keele University, Keele, Staffordshire, UK 2. Midlands Centre for Spinal Injuries, RJAH Orthopaedic Hospital, Oswestry, Shropshire, UK. (1)
Nencki Institute of Experimental Biology, Warsaw, Poland (1)

Tags

xref:PubMed:32226812 (2)
xref:PubMed:40338665 (2)
xref:PubMed:31175296 (1)
xref:PubMed:42309342 (1)
xref:PubMed:22133879 (1)
xref:PubMed:39733145 (1)
xref:PubMed:33869277 (1)

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PROTEOMIC IDENTIFICATION OF SYSTEMIC BIOMARKERS IN RAT MODELS OF SPINAL CORD INJURY

Biomarkers to more accurately determine severity and prognosis following spinal cord injury (SCI) are needed to ensure that patients are assigned to the most suitable treatment and rehabilitation regimes. This study aimed to characterise the blood proteome following SCI in clinical rat injury models...

ORGANISM(S): Rattus norvegicus (Rat)

2022-05-19 | PXD021137 | Pride

Time series gene expression data from adult rat tail MNs following spinal cord transection

Spinal cord injury leads to impaired motor and sensory functions. After spinal cord injury there is a an initial phase of hypo-reflexia followed by a developing hyper-reflexia, often termed spasticity. Previous studies have suggested a relationship between the reappearance of plateau potentials in m...

ORGANISM(S): Rattus norvegicus

2010-05-27 | E-GEOD-19701 | biostudies-arrayexpress

Expression data from adult rat tail MNs after spinal cord transection

ORGANISM(S): Rattus norvegicus

2009-10-31 | E-GEOD-16710 | biostudies-arrayexpress

Transcription profiling of mouse lateral, medial and intermediolateral column motoneurons following spinal cord transection

To determine spinal cord injury (SCI) induced changes in gene expression, laser capture microscopy (LCM) and Affymetrix microarrays were used to profiles three distinct populations of motor neurons (MNs) in five sets of littermates. In each set, one littermate received a lamenectomy (sham operated),...

ORGANISM(S): Mus musculus

2009-09-25 | E-GEOD-18179 | biostudies-arrayexpress

Skeletal Muscle Contraction Reduces Effects of Unloading on Bone Independently from the Central Nervous System: Studies Using Functional Electrical Stimulation after Spinal Cord Transection

Spinal cord injury (SCI) causes severe bone loss and disrupts connections between higher centers in the central nervous system (CNS) and bone. Muscle contraction elicited by functional electrical stimulation (FES) partially protects against loss of bone but cellular and molecular events by which th...

ORGANISM(S): Rattus norvegicus

2012-06-27 | E-GEOD-30301 | biostudies-arrayexpress

Complete rat spinal cord transection as a faithful model of spinal cord injury for translational cell transplantation.

Not available

S-EPMC5381701 | biostudies-literature

Effects of a High-Fat Diet on Tissue Mass, Bone, and Glucose Tolerance after Chronic Complete Spinal Cord Transection in Male Mice.

Not available

S-EPMC8240892 | biostudies-literature

Expression of long non-coding RNAs in complete transection spinal cord injury: a transcriptomic analysis.

Not available

S-EPMC7059563 | biostudies-literature

Gene profiling of intermediolateral column, medial, and lateral motoneuron after spinal cord transection