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GenomicsDistinct roles of COPI proteins attenuated with cell senescence
Distinct roles of COPI proteins attenuated with cell senescence
PRJNA1290371 | ENA
GenomicsEffect of COPI depletion on senescence model systems
Effect of COPI depletion on senescence model systems
PRJNA929513 | ENA
ProteomicsProteomic Profiling of Mammalian COPI Vesicles
By combining in vitro COPI vesicle reconstitutions and SILAC-based mass spectrometric analysis this study aims to identify the core proteome of mammalian COPI vesicles. Furthermore proteomes generated from vesicles with γ- and ζ-COP as well as Arf isoforms have been investigated with the same approa...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2022-02-23 | PXD012129 | Pride
Silac Copi vesicels Proteomics 
TranscriptomicsDistinct roles of COPI proteins attenuated with cell senescence
Cellular senescence is characterized by persistent cell cycle arrest, apoptosis resistance, and widespread changes in gene expression. Although the functional alterations in organelles like mitochondria and lysosomes are well characterized, senescence-associated changes in the structure and function...
ORGANISM(S): Homo sapiens 
2026-06-11 | GSE302417 | GEO
TranscriptomicsEffect of COPI depletion on senescence model systems
To examine effects of COPI depletion on senescence transcriptional signatures we generated cell lines (IMR90 or IMR90 ER:RAS cells) with inducible 2 COPI shRNAs or control shRNAs and induced to senesce with either treatment with Bleomycin or 4OHT treatment. Transcriptional analysis was performed 3 d...
ORGANISM(S): Homo sapiens 
2023-09-28 | GSE224070 | GEO
ProteomicsCOPI membrane interactome by ultraID-MS
Analysis of a membrane-bound COPI interactome by comparing gammaCOP-ultraID datasets with or without incubation with brefeldin A (POI = gamma1COP or gamma2COP, control protein = Ago2). Three biological replicates per condition.
ORGANISM(S): Mus musculus (Mouse) 
2022-07-05 | PXD026715 | Pride
Ultraid pdb copi 
ProteomicsLEPROTs bud into COPI vesicles with specific clients
To investigate whether some COPI vesicles contain LEPROTs and whether LEPROT-enriched vesicles carry specific clients
ORGANISM(S): Homo Sapiens 
2024-11-12 | PXD057776 |
UnknownCOPI selectively drives maturation of the early Golgi.
Not available
S-EPMC4758959 | biostudies-literature
UnknownCOPI is required for enterovirus 71 replication.
Not available
S-EPMC3360637 | biostudies-literature
UnknownCOPI Vesicle Disruption Inhibits Mineralization via mTORC1-Mediated Autophagy.
Not available
S-EPMC10779376 | biostudies-literature
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