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GenomicsUbiquitin-dependent remodeling of the actin cytoskeleton drives cell fusion
Ubiquitin-dependent remodeling of the actin cytoskeleton drives cell fusion
PRJNA679071 | ENA
TranscriptomicsComparative transcriptome analysis of DFAT cells after the treatment with Y-27632 and the transfection of Mkl1 siRNA
Cellular differentiation is regulated through activation and repression of defined transcription factors. A hallmark of differentiation is a pronounced change in cell shape, which is determined by dynamics of the actin cytoskeleton. In de-differentiated fat (DFAT) cells and 3T3-L1 cells, we showed t...
ORGANISM(S): Mus musculus 
2014-03-28 | E-GEOD-52334 | biostudies-arrayexpress
ProteomicsSuccinyl-proteome profiling reveals HDAC8-mediated CAPZB desuccinylation regulates cytoskeleton remodeling in bleomycin-induced idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disease of unknown etiology, characterized by progressive scarring and fibrosis of the lungs, leading to irreversible loss of lung function. Current mechanism studies have found that fibroblasts, as the main effector cells, exhibit ab...
ORGANISM(S): Mus musculus (Mouse) 
2026-04-30 | PXD075455 | Pride
Idiopathic pulmonary fibrosis  lysine succinylation  succinyl-proteome  capzb  hdac8  cytoskeleton remodeling  lc-ms/ms  mouse lung tissue 
GenomicsMethylation of HBP1 by PRMT1 inhibits its tumor-suppressive function through regulating 2 GSN-mediated actin cytoskeleton remodeling
Methylation of HBP1 by PRMT1 inhibits its tumor-suppressive function through regulating 2 GSN-mediated actin cytoskeleton remodeling
PRJNA848384 | ENA
UnknownIntrinsic Resistance of Chronic Lymphocytic Leukemia Cells to NK Cell-Mediated Lysis Can Be Overcome In Vitro by Pharmacological Inhibition of Cdc42-Induced Actin Cytoskeleton Remodeling.
Not available
S-EPMC8181408 | biostudies-literature
GenomicsFrequent alterations in cytoskeleton remodeling genes in primary and metastatic Chinese lung adenocarcinomas
The landscape of genetic alterations in lung adenocarcinoma derived from Asian patients is largely uncharacterized. Here we present an integrated genomic and transcriptomic analysis of 335 primary lung adenocarcinomas and 35 corresponding lymph node metastases from Chinese patients. Altogether 13 si...
EGAS00001000982 | EGA
ProteomicsSecretome of rat smooth muscle cells with stretch
The extracellular matrix (ECM) is fundamental to cellular and tissue structural integrity and provides mechanical cues to initiate diverse biological functions1. The quality and quantity of ECM determines tissue stiffness and controls gene expression, cell fate, and cell cycle progression in various...
ORGANISM(S): Rattus Rattus (black Rat) 
2020-03-18 | PXD013915 | JPOST Repository
ProteomicsEvidence for a Nuclear Role for Drosophila Dlg as a Regulator of the NURF Complex
Scrib, Dlg, and Lgl are basolateral regulators of epithelial polarity and tumor suppressors whose molecular mechanisms of action remain unclear. We used proximity biotinylation to identify proteins localized near Dlg in the Drosophila wing imaginal disc epithelium. In addition to expected membrane- ...
ORGANISM(S): Drosophila Melanogaster (ncbitaxon:7227) 
2021-04-13 | MSV000087186 | MassIVE
UnknownHGF Modulates Actin Cytoskeleton Remodeling and Contraction in Testicular Myoid Cells.
Not available
S-EPMC5344232 | biostudies-literature
UnknownNuclear Morphological Remodeling in Human Granulocytes Is Linked to Prenylation Independently from Cytoskeleton.
Not available
S-EPMC7699803 | biostudies-literature
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