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MetabolomicsPlasma metabolome alteration in dairy cows with left displaced abomasum before and after surgical correction
Left displaced abomasum (LDA) leads to substantial changes in the metabolism of dairy cows. Surgical correction of LDA can rapidly improve the health of cows; however, changes in metabolism following surgery are rarely described. To investigate the changes of plasma metabolome in cows with LDA befor...
2022-08-17 | MTBLS4126 | MetaboLights
MetabolomicsPlasma metabolite changes in dairy cows during parturition identified using untargeted metabolomics
The metabolic responses of cows undergo substantial changes during the transition from late pregnancy to early lactation. However, the molecular mechanisms associated with these changes in physiological metabolism have not been clearly elucidated. The objective of this study was to investigate metab...
2019-08-20 | MTBLS809 | MetaboLights
MetabolomicsPrevotella vs. Ruminococcus enterotypes drive divergent milk fat synthesis in dairy cows through rumen microbiota-host metabolic crosstalk

Background: High-yield dairy cows are usually accompanied with lower milk fat (MF) rate, with huge variations in MF contents among individuals. The potential mechanisms of key microorganisms, their genes and metabolites participate in MF synthesis are still not well understood. By selec...

2025-10-28 | MTBLS13211 | MetaboLights
TranscriptomicsElevated dairy fat intake in lactating women alters milk lipid and fatty acids without detectible changes in expression of genes related to lipid uptake or synthesis
Previous work has demonstrated that elevated maternal lipid intake (particularly from dairy products) is associated with increased lipids and altered fatty acid profile in milk produced by healthy lactating women. We investigate our primary hypothesis that a maternal diet rich in full-fat dairy prod...
ORGANISM(S): Homo sapiens 
2015-02-24 | E-GEOD-66191 | biostudies-arrayexpress
TranscriptomicsEffect of lactation on transcriptomic expression in bovine adipose tissue
The objective was to study the transcriptomic changes in adipose tissue in the early stages of lactation, specifically in Bos Taurus, Holstein dairy cattle as a function of milk production and genetic merit. Chip quality backgrounds averaged below 50 units, and 3'/5' bias on control genes < 2.0. Cor...
ORGANISM(S): Bos taurus 
2010-05-27 | E-GEOD-21535 | biostudies-arrayexpress
MetabolomicsMetabonomic analysis of human and 12 kinds of livestock mature milk

Mature milk, as a nutrient-rich endogenous metabolite, has various beneficial effects on the human body. In order to investigate the specific nutrients provided by different dairy products to humans, we used UHPLC-Q-TOF MS to analyze the highly significantly differentially expressed metabolites i...

2023-08-21 | MTBLS6777 | MetaboLights
UnknownComprehensive Characterization of Serum Lipids of Dairy Cows: Effects of Negative Energy Balance on Lipid Remodelling.
Not available
S-EPMC12029815 | biostudies-literature
TranscriptomicsNegative energy balance and splenic gene expression patterns in high yielding dairy cows during the early postpartum period [spleen]
Increased energy demands to support lactation, coupled with lowered feed intake capacity results in negative energy balance (NEB) and is typically characterized by extensive mobilization of body energy reserves in the early postpartum dairy cow. The catabolism of stored lipid leads to an increase i...
ORGANISM(S): Bos taurus 
2014-04-08 | E-GEOD-56589 | biostudies-arrayexpress
TranscriptomicsMammary gene expression profile of goats receiving high or low forage diets supplemented or not with lipids
Animal nutrition considerably affects milk composition that influences its nutritional quality. Milk component synthesis and secretion by the mammary gland involve the expression of a large number of genes whose nutritional regulation remains poorly defined. In this study, 16 lactating goats receive...
ORGANISM(S): Capra hircus 
2009-11-29 | E-GEOD-11592 | biostudies-arrayexpress
UnknownMilk Lipids as Bioactive Modulators of the Bacterial Proteome: Mechanisms Linking Dairy Management to Microbial Performance.
Not available
S-EPMC12896685 | biostudies-literature
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