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UnknownA subpathway-based method of drug reposition for polycystic ovary syndrome.
Not available
S-EPMC4812690 | biostudies-literature
TranscriptomicsExpression of the IL-17/Th17 axis in the development of acute renal allograft rejection
Genesets for the IL-17 pathway and Th17 T-helper cell subtype showed increasing enrichment in 33 pre-transplant donor biopsies and 33 matching post-transplant biopsies from patients with increasing Banff grades of acute rejection (no signficant abnormalities, n=17; borderline, n=4; ARIA, n=7; ARIB, ...
ORGANISM(S): Homo sapiens 
2014-01-01 | E-GEOD-34437 | biostudies-arrayexpress
TranscriptomicsDownstream Signaling Modeling of Cancer Signaling Pathways Enables Systematic Drug Respositioning for Subtypes of Breast Cancer Metastases
Gene Expression Profiling of Breast Cancer Patients with Brain Metastases Brain metastases confer the worst prognosis of breast cancer as no therapy exists that prevents or eliminates the cancer from spreading to the brain. We developed a new computational modeling method to derive specific downstr...
ORGANISM(S): Homo sapiens 
2013-05-15 | E-GEOD-46928 | biostudies-arrayexpress
UnknownAnterolateral advancement pharyngoplasty versus barbed reposition pharyngoplasty in patients with obstructive sleep apnea.
Not available
S-EPMC10943148 | biostudies-literature
TranscriptomicsExpression data from 786-O renal cell cancer cells treated with pentamidine
While early stages of clear cell renal cell carcinoma (ccRCC) are curable, survival outcome for metastatic ccRCC remains poor. The purpose of the current study was to apply a new individualized bioinformatics analysis (IBA) strategy to these transcriptome data in conjunction with Gene Set Enrichment...
ORGANISM(S): Homo sapiens 
2014-08-05 | E-GEOD-54709 | biostudies-arrayexpress
Unknownβ-Secretase-1: In Silico Drug Reposition for Alzheimer's Disease.
Not available
S-EPMC10179340 | biostudies-literature
ProteomicsAntibacterial Activities and Action Mode of Anti-hyperlipidemic Lomitapide Against Staphylococcus aureus_1
Lomitapide has been approved by FDA for years in reducing levels of low-density lipoprotein (LDL) in cases of familial hypercholesterolemia, whereas the antibacterial effect of lomitapide remains elusive. In this study, the inhibitory activities of lomitapide against Staphylococcus aureus, including...
ORGANISM(S): Staphylococcus aureus 
2022-03-29 | PXD031706 | Pride
Staphylococcus aureus  lomitapide  antibiotic resistance  drug reposition 
UnknownReposition of the anti-inflammatory drug diacerein in an in-vivo colorectal cancer model.
Not available
S-EPMC8802128 | biostudies-literature
UnknownReposition of the Fungicide Ciclopirox for Cancer Treatment.
Not available
S-EPMC9175535 | biostudies-literature
UnknownDrug-target interactions prediction using marginalized denoising model on heterogeneous networks.
Not available
S-EPMC7653902 | biostudies-literature
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