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BioID proximity proteomics of wild-type and ΔPDZ DVL2 in HEK293 Flp-In T-REx cells

This dataset supports a study investigating how the PDZ domain of Dishevelled-2 (DVL2) specifies β-catenin-independent Wnt signalling outputs. BioID proximity labelling was performed in HEK293 Flp-In T-REx cells stably expressing BirA*-tagged wild-type DVL2 or a matched DVL2 mutant lacking the PDZ d...

ORGANISM(S): Homo sapiens (Human)

2026-09-12 | PXD079793 | Pride

The LINC01612-DVL2-WNT axis promotes human endoderm differentiation

PRJNA1235743 | ENA

The LINC01612-DVL2-WNT axis promotes human endoderm differentiation

Long noncoding RNA in gene desert regions are largely uncharacterized despite their potential regulatory roles in cell differentiation. Here, we identify LINC01612 as a crucial modulator of human definitive endoderm differentiation. LINC01612 exhibits stage-specific expression without protein coding...

ORGANISM(S): Homo sapiens

2025-09-23 | GSE291901 | GEO

PP5 (PPP5C) is a phosphatase of Dvl2.

Not available

S-EPMC5807433 | biostudies-literature

The LINC01612-DVL2-WNT axis promotes human endoderm differentiation.

Not available

S-EPMC12790727 | biostudies-literature

USP9X Deubiquitylates DVL2 to Regulate WNT Pathway Specification.

Not available

S-EPMC6884140 | biostudies-literature

Endogenous oligomer formation underlies DVL2 condensates and promotes Wnt/β-catenin signaling.