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Dynamical Modeling of Secondary Metabolism and Metabolic Switches in Streptomyces xiamenensis 318
Mangrove-derived Streptomyces xiamenensis 318, with a relatively compact genome and simpler secondary metabolism, is used as model organism in our investigation. We performed integrated studies of metabolic dynamical modeling, transcriptome level measurements, and metabolic profiling experiments on ...
ORGANISM(S): Streptomyces xiamenensis 
Dynamical modeling reveals RNA decay mediates the effect of matrix stiffness on aged muscle stem cell fate
Loss of muscle stem cell (MuSC) self-renewal with aging reflects a combination of influences from the intracellular (e.g., post-transcriptional modifications) and extracellular (e.g., matrix stiffness) environment. Whereas conventional single cell analyses have revealed valuable insights into factor...
ORGANISM(S): Mus musculus 
2025-09-24 | GSE225583 | GEO
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