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MetabolomicsCharacterization Epstein-Barr Virus-Associated Encephalitis via Identification of Metabolomic Biomarkers

Objective: Fulminant Epstein-Barr Virus (EBV) infection may lead to fatal outcomes in patients with EBV-associated encephalitis (EBVAE). To investigate potential biomarkers in EBVAE, we utilized an untargeted metabolomic methodology to identify disease-associated biomarkers in patients ...

2026-03-23 | MTBLS14111 | MetaboLights
MetabolomicsPseudorabies Virus Triggers Ferritinophagy-Mediated Ferroptosis and Neuroinflammation in Viral Encephalitis

Pseudorabies virus (PRV), a member of the Alphaherpesvirinae subfamily, primarily infects pigs and poses a significant threat to the swine industry. In recent years, emerging PRV variants have been reported to infect humans, predominantly causing encephalitis. Ferroptosis is a recently identified...

2026-04-17 | MTBLS12373 | MetaboLights
MetabolomicsSimultaneous Membrane and RNA Binding by Tick-Borne Encephalitis Virus Capsid Protein

Tick-borne encephalitis virus is an enveloped, pathogenic, RNA virus in the family Flaviviridae, genus Flavivirus. Viral particles are formed when the nucleocapsid, consisting of an RNA genome and multiple copies of the capsid protein, buds through the endoplasmic reticulum membrane and acquires ...

2023-01-06 | MTBLS6076 | MetaboLights
TranscriptomicsSIV Encephalitis and Uninfected Control: Hippocampus Expression Profiles
HIV-associated dementia (HAD) is a syndrome occurring in HIV-infected patients with advanced disease that likely develops as a result of macrophage and microglial activation as well as other immune events triggered by virus in the central nervous system. The most relevant experimental model of HAD, ...
ORGANISM(S): Macaca mulatta 
2010-04-03 | E-GEOD-13824 | biostudies-arrayexpress
GenomicsJapanese encephalitis virus
Japanese encephalitis virus Genome sequencing
PRJNA871976 | ENA
TranscriptomicsRibosome profiling of Japanese encephalitis virus infected Neuro2a cells
Ribosome profiling (Ribo-Seq) and RNA-Seq analysis of mouse neuroblastoma (Neuro2a) cells infected with Japanese Encephalitis Virus (JEV) P20778 Vellore strain. At 18 h post infection (p.i.), infected cells were treated with either cycloheximide (translation elongation inhibitor) or in combination w...
ORGANISM(S): Mus musculus 
2021-07-05 | E-MTAB-9352 | biostudies-arrayexpress
TranscriptomicsmRNA expression profile in CHME3 cells infected with Japanese encephalitis virus
CHME3 cells grown on six-wells were infected with Japanese encephalitis virus (JEV) (P20778 strain ) and total RNA was isolated from cells at 6, 24 and 48 h of post infection mRNA expression was significantly altered in JEV infected human microglial cells. A time dependant change in microRNA profile...
ORGANISM(S): Homo sapiens 
2015-01-01 | E-GEOD-57330 | biostudies-arrayexpress
TranscriptomicsMicroRNA expression profile in CHME3 cells infected with Japanese encephalitis virus
CHME3 cells grown on six-wells were infected with Japanese encephalitis virus (JEV) (P20778 strain), and total RNA was isolated from cells at 6, 24 and 48 h of post infection. MicroRNA expression was significantly altered in JEV-infected human microglial cells. A time-dependent change in microRNA pr...
ORGANISM(S): Homo sapiens 
2015-01-01 | E-GEOD-57410 | biostudies-arrayexpress
GenomicsJapanese encephalitis virus
Japanese encephalitis virus Genome sequencing and assembly
PRJNA855038 | ENA
GenomicsVenezuelan equine encephalitis virus
Venezuelan equine encephalitis virus Genome sequencing
PRJNA438670 | ENA
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