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ProteomicsEndothelial-secreted Endocan protein activates PDGFRa signaling and regulates vascularity, radioresistance, and regional phenotype in glioblastoma
Extensive neovascularization is a hallmark of glioblastoma (GBM). In addition to supplying oxygen and nutrients, vascular endothelial cells provide trophic support to GBM cells via paracrine signaling. Here we report that Endocan (ESM1), an endothelial-secreted proteoglycan, confers enhanced prolife...
ORGANISM(S): Homo sapiens (Human) 
2024-12-04 | PXD057635 | Pride
Brain cancer  glioma  glioblastoma  endocan  esm1  pdgfra  myc  angiogenesis  endothelial cells  radioresistance 
UnknownEndocan in Acute Leukemia: Current Knowledge and Future Perspectives.
Not available
S-EPMC9027427 | biostudies-literature
UnknownBlood endocan as a biomarker for breast cancer recurrence.
Not available
S-EPMC11495321 | biostudies-literature
UnknownEndocan as a marker of microvascular inflammation in kidney transplant recipients.
Not available
S-EPMC6372712 | biostudies-literature
UnknownCan endocan serve as a molecular "hepatostat" in liver regeneration?
Not available
S-EPMC9972723 | biostudies-literature
UnknownSystematic Review of Endocan as a Potential Biomarker of COVID-19.
Not available
S-EPMC9895317 | biostudies-literature
UnknownEndocan, sepsis, pneumonia, and acute respiratory distress syndrome.
Not available
S-EPMC6204032 | biostudies-literature
TranscriptomicsEndothelial-secreted Endocan protein acts as a PDGFR alpha ligand and regulates vascularity, radioresistance, and regional phenotype in glioblastoma [2]
One of the hallmarks of glioblastoma (GBM) is extensive neovascularization. In addition to supplying blood and nutrients, vascular endothelial (VE) cells provide trophic support to GBM cells via paracrine signaling, the precise mechanisms of which are being unraveled. Here, using patient-derived GBM...
ORGANISM(S): Homo sapiens 
2024-10-30 | GSE277014 | GEO
TranscriptomicsEndothelial-secreted Endocan protein acts as a PDGFR alpha ligand and regulates vascularity, radioresistance, and regional phenotype in glioblastoma [1]
One of the hallmarks of glioblastoma (GBM) is extensive neovascularization. In addition to supplying blood and nutrients, vascular endothelial (VE) cells provide trophic support to GBM cells via paracrine signaling, the precise mechanisms of which are being unraveled. Here, using patient-derived GBM...
ORGANISM(S): Homo sapiens 
2024-10-30 | GSE277011 | GEO
UnknownPlasma Endocan as a Biomarker of Thrombotic Events in COVID-19 Patients.
Not available
S-EPMC9572304 | biostudies-literature
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