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MetabolomicsMetabolome of pig endometrium and placenta.

Neonatal mortality is mostly due to a reduced piglet maturity. An essential question for adaptation to extra-uterine environment lies in the optimization of the crosstalk between maternal and fetal genomes for a distribution of resources that allows fetuses to express healthier phenotypes at birt...

2025-06-30 | MTBLS3091 | MetaboLights
TranscriptomicsRNA-seq of estrogen (E2) induced changes of mRNA expression in early pregnant Sus scrofa endometrium
Maternal exposure to estrogens can induce long-term adverse effects in the offspring. This may be mediated through alterations in the endometrium affecting embryo-maternal communication as early as the preimplantational phase. Thus, we analyzed the effects of gestational estradiol-17β (E2) exposure ...
ORGANISM(S): Sus scrofa 
2018-10-16 | E-MTAB-6242 | biostudies-arrayexpress
TranscriptomicsMessenger RNA profiling of bovine endometrium during the estrous cycle using a custom-made cDNA array
The endometrium provides optimal conditions for the transport of sperm to the oviduct, to the site of fertilization, and later on for the reception of the embryo. To study these changes on the level of gene expression, a messenger RNA expression profiling of endometrium tissue samples collected from...
ORGANISM(S): Bos taurus 
2010-05-27 | E-GEOD-8337 | biostudies-arrayexpress
TranscriptomicsBovine endometrium at day 18 of pregnancy after transfer of in vitro produced or somatic cell nuclear transfer embryos
Although somatic cell nuclear transfer (SCNT) cloning is more efficient in bovine than in all other species tested so far, there is a high rate of pregnancy failure that has been linked to structural and functional abnormalities of the placenta. We tested the hypothesis that these changes may origin...
ORGANISM(S): Bos taurus 
2009-03-12 | E-GEOD-13663 | biostudies-arrayexpress
TranscriptomicsDifferential expression of microRNAs between eutopic and ectopic endometrium in ovarian endometriosis
Endometriosis is defined as the presence of endometrial tissue (eutopic tissue) outside the uterus (ectopic tissue). We assessed differentially expressed microRNAs in ectopic endometrium compared with eutopic endometrium. Comparison of paired eutopic/ectopic endometrium microRNAs from three patients...
ORGANISM(S): Homo sapiens 
2010-12-30 | E-GEOD-26346 | biostudies-arrayexpress
TranscriptomicsDiscovery of candidate genes and pathways in the endometrium regulating ovine blastocyst growth and conceptus elongation
Establishment of pregnancy in ruminants requires blastocyst growth to form an elongated conceptus that produces interferon tau, the pregnancy recognition signal, and initiates implantation. Blastocyst growth and development requires secretions from the uterine endometrium. An early increase in circu...
ORGANISM(S): Ovis aries 
2010-05-15 | E-GEOD-17401 | biostudies-arrayexpress
TranscriptomicsComparison of the effects of early pregnancy with human interferon, alpha 2 (IFNA2) on gene expression in bovine endometrium
Interferon tau (IFNT), a Type I IFN similar to alpha IFNs (IFNA), is the pregnancy recognition signal, produced by the ruminant conceptus. To elucidate specific effects of bovine IFNT and of other conceptus-derived factors, endometrial gene expression changes during early pregnancy were compared to ...
ORGANISM(S): Bos taurus 
2011-10-31 | E-GEOD-30694 | biostudies-arrayexpress
TranscriptomicsExpression data of human decidual NK cells from gravid uteri and NK cells from cycling endometrium
Human NK cells from the decidua basalis of gravid uteri (dNK) and from cycling endometrium (eNK) of women undergoing hysterectomy were isolated and compared by gene expression profiling using Affymetrix microarrays with probes representing ~47,400 transcripts. Substantial differences indicate th...
ORGANISM(S): Homo sapiens 
2010-03-09 | E-GEOD-20499 | biostudies-arrayexpress
TranscriptomicsGene expression profile for ectopic vs. eutopic endometrium
Endometriosis is a common gynecological disorder characterized by pain and infertility, where the lesions disseminate everywhere in the body with a preference for the pelvis. In that, it could be regarded as a “benign metastatic disease”, since its issue is not fatal. However, the molecular base...
ORGANISM(S): Homo sapiens 
2010-06-19 | E-GEOD-12768 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human endometrium from patients with a history of endometriosis vs. normal controls sampled at a range of menstrual cycle timepoints reveals progesterone resistance and candidate susceptibility genes in women with endometriosis
The transition of regularly cycling endometrium from the proliferative or Estrogen-dominant phase of the menstrual cycle to the Progesterone-dominant Early and Mid Secretory phases requires wide-spread changes in gene expression that shift the endometrium from a proliferative capacity to a different...
ORGANISM(S): Homo sapiens 
2008-04-09 | E-GEOD-6364 | biostudies-arrayexpress
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