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To counter projected reductions in yields of the major crop barley, it is essential to elucidate the mechanisms of its resilience. To assist such efforts, we collected grains from plants grown in fields at 12 testing stations, with suitable temperature and precipitation gradients for identifying ...

2023-03-07 | MTBLS5778 | MetaboLights

With the global rise in aging populations, the increasing incidence of neurodegenerative diseases underscores concerns about brain health, with pesticides like rotenone, emerging as key environmental hazardous. The precise mechanism by which chronic environmental concentration of rotenone exposur...

2025-01-28 | MTBLS11699 | MetaboLights
Acting as chemical defense or signaling compounds, secondary metabolites (SMs) play an essential role in the evolutionary success of many angiosperm plant families. However, the adaptive advantages that SMs confer, and the influence of environmental and developmental factors on SMs expression, remai...
2020-03-24 | MTBLS840 | MetaboLights

As emerging environmental contaminants, rare earth elements (REEs) pose a growing ecotoxicological threat, making a mechanistic understanding of their toxicity in aquatic primary producers like microalgae crucial for accurate ecological risk assessment. This study investigated the multi-level adv...

2025-09-03 | MTBLS12918 | MetaboLights

Background: Capsaicin, a natural alkaloid in chili peppers, regulates glycemic levels, however, its mechanisms and therapeutic potential remain unclear. This study aimed to elucidate the role of gut microbiota and their metabolites in mediating capsaicin’s glycemic regulatory effects. We conducte...

2025-06-13 | MTBLS12575 | MetaboLights
This SuperSeries is composed of the following subset Series: GSE25895: Paternally-induced transgenerational environmental reprogramming of metabolic gene expression in mammals (dye swap) GSE25896: Paternally-induced transgenerational environmental reprogramming of metabolic gene expression in mammal...
ORGANISM(S): Mus musculus 
Epigenetic information can be inherited through the mammalian germline, and represents a plausible transgenerational carrier of environmental information. To test whether transgenerational inheritance of environmental information occurs in mammals, we carried out an expression profiling screen for g...
ORGANISM(S): Mus musculus 
Epigenetic information can be inherited through the mammalian germline, and represents a plausible transgenerational carrier of environmental information. To test whether transgenerational inheritance of environmental information occurs in mammals, we carried out an expression profiling screen for g...
ORGANISM(S): Mus musculus 
Brown1997 - Plasma Melatonin Levels A mathematical model that incorporates a piecewise function for NAT activity to predict melatonin concentration. This model is described in the article: A mathematical model of diurnal variations in human plasma melatonin levels. Brown EN, Choe ...
2024-09-02 | BIOMD0000000672 | BioModels
ADHD is the most common neurobehavioral disorder in school-aged children. In addition to genetic factors, environmental influences or gene x environmental interactions also play an important role in ADHD. One example of a well studied environmental risk factor for ADHD is exposure to polychlorinated...
ORGANISM(S): Rattus norvegicus 
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