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MetabolomicsSingle-cell lipidomic analysis of the Epithelial-Mesenchymal Transition (EMT) using MALDI-MSI

EMT is a metastasis-promoting process whose heterogeneity has been extensively studied at a gene expression level. EMT also involves reprogramming of lipid metabolism, however there has been little focus on heterogeneity on the lipid level. Here, we use MALDI-MSI to determine the levels of variou...

2026-04-15 | MTBLS12650 | MetaboLights
TranscriptomicsCAMK1D amplification implicated in epithelial-mesenchymal transition in basal-like breast cancer
This SuperSeries is composed of the following subset Series: GSE12811: CAMK1D amplification implicated in epithelial-mesenchymal transition in basal-like breast cancer (expr) GSE12813: CAMK1D amplification implicated in epithelial-mesenchymal transition in basal-like breast cancer (aCGH) Refer to in...
ORGANISM(S): Homo sapiens 
2009-09-08 | E-GEOD-12827 | biostudies-arrayexpress
OtherExtracellular remodelling during oncogenic Ras-induced epithelial-mesenchymal transition facilitates MDCK cell migration.
PeptideAtlas ID: PAe003680. Original data file: O070224-30.mgf. Data published as part of J Proteome Res. 2010 Feb 5;9(2):1007-19 . From the Abstract: {{i}}... To gain insights into extracellular mediators associated with EMT, we conducted an extensive proteomic analysis of the secretome from MDCK ...
ORGANISM(S): Dog, Canine_adenovirus, Canine_calicivirus, Canine_distemper_virus, Canine_minute_virus, Canine_oral_papillomavirus, Canine_papillomavirus_2, Canine_papillomavirus___3, Canine_papillomavirus___4, Canine_parvovirus 
GPM11210000341 | GPMDB
TranscriptomicsGene expression profiling of NSCLC cell lines upon TGFb-induced epithelial-mesenchymal transition (EMT)
Epithelial-mesenchymal transition has been implicated in tumor metastasis, cancer drug resistance and cancer stem cell features. In this study, we examined gene expression profiles of three non-small cell lung cancer cell lines, before and after experimentally induced EMT. We modeled epitheial-mese...
ORGANISM(S): Homo sapiens 
2014-11-19 | E-GEOD-49644 | biostudies-arrayexpress
TranscriptomicsSWI/SNF Chromatin-Remodeling Factor Smarcd3/Baf60c Controls Epithelial-Mesenchymal Transition by Inducing Wnt5a Signaling
We previously identified a gene signature predicted to regulate the epithelial-mesenchymal transition (EMT) in both epithelial tissue stem cells and breast cancer cells. A phenotypic RNA interference (RNAi) screen identified the genes within this 140-gene signature that promoted the conversion of me...
ORGANISM(S): Homo sapiens 
2013-08-19 | E-GEOD-40145 | biostudies-arrayexpress
TranscriptomicsCAMK1D amplification implicated in epithelial-mesenchymal transition in basal-like breast cancer (expr)
Title: CAMK1D amplification implicated in epithelial-mesenchymal transition in basal-like breast cancer Summary: Breast cancer exhibits clinical and molecular heterogeneity, where expression-profiling studies have identified five major molecular subtypes. The basal-like subtype, expressing basal e...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-12811 | biostudies-arrayexpress
TranscriptomicsPrognostic signature of epithelial-mesenchymal transition in breast cancer
Epithelial-mesenchymal transition (EMT), a switch of polarized epithelial cells to a migratory, fibroblastoid phenotype, is considered a key process driving tumor cell invasiveness and metastasis. Using breast cancer cell lines as a model system, we sought to discover gene-expression signatures of ...
ORGANISM(S): Homo sapiens 
2010-04-11 | E-GEOD-13915 | biostudies-arrayexpress
TranscriptomicsCAMK1D amplification implicated in epithelial-mesenchymal transition in basal-like breast cancer (aCGH)
Title: CAMK1D amplification implicated in epithelial-mesenchymal transition in basal-like breast cancer Summary: Breast cancer exhibits clinical and molecular heterogeneity, where expression-profiling studies have identified five major molecular subtypes. The basal-like subtype, expressing basal e...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-12813 | biostudies-arrayexpress
TranscriptomicsMAP3K4/CBP Regulated H2B acetylation Controls Epithelial-Mesenchymal Transition in Trophoblast Stem Cells
Epithelial stem cells self-renew while maintaining multipotency, but the dependence of stem cell properties on maintenance of the epithelial phenotype is unclear. We previously showed that trophoblast stem (TS) cells lacking the protein kinase MAP3K4 maintain properties of both stemness and epitheli...
ORGANISM(S): Mus musculus 
2011-05-27 | E-GEOD-27883 | biostudies-arrayexpress
TranscriptomicsChanges in gene expression during epithelial-mesenchymal transition in a breast cancer primary culture
Epithelial-Mesenchymal Transition (EMT) is an important process during normal development, but also co-opted by various cancer cells to enable them to invade and form metastases at distant sites. In this study, we examinated changes in gene expression during EMT in breast cancer using primary cultu...
ORGANISM(S): Homo sapiens 
2014-06-02 | E-GEOD-53175 | biostudies-arrayexpress
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