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MetabolomicsMetabolomic and Proteomic Stratification of Equine Osteoarthritis

Osteoarthritis (OA) is characterised by loss of articular cartilage, synovial membrane dysfunction and subchondral sclerosis. Few studies have used a global approach to stratify equine synovial fluid (SF) molecular profiles according to OA severity. SF was collected from 58 metacarpophalangeal (M...

2025-10-16 | MTBLS1645 | MetaboLights
MetabolomicsEx-Vivo Equine Cartilage Explant Osteoarthritis Model - A Metabolomics and Proteomics Study
Osteoarthritis (OA) is an age-related degenerative musculoskeletal disease characterised by loss of articular cartilage, synovitis, abnormal bone proliferation and subchondral bone sclerosis. Underlying OA pathogenesis is yet to be fully elucidated with no OA specific biomarkers in clinical use. Ex-...
2020-09-30 | MTBLS1495 | MetaboLights
TranscriptomicsStructural annotation of equine protein-coding genes determined by mRNA sequencing
The horse, like a majority of animal species, has a limited amount of species-specific expressed sequence data available in public databases. As a result, structural models for a majority of genes defined in the equine genome are predictions based on ab initio sequence analysis or the projection of...
ORGANISM(S): Equus caballus 
2010-11-10 | E-GEOD-21925 | biostudies-arrayexpress
TranscriptomicsAnalysis of Unannotated Equine Transcripts Identified by mRNA Sequencing
Horse-specific genes are not readily identified from available equine EST/cDNA resources due to relatively limited coverage. In addition, equine gene sets predicted in silico by Ensembl and NCBI will not identify horse specific genes since they rely on homology-based projection of gene structure ann...
ORGANISM(S): Equus caballus 
2013-07-30 | E-GEOD-46858 | biostudies-arrayexpress
MetabolomicsThe gut microbiota influence the basal physiological parameters in equine athletes
Not available
ORGANISM(S): Equus caballus 
ST000945 | MetabolomicsWorkbench
TranscriptomicsGlobal gene expression changes during the estrous cycle in equine endometrium
The equine endometrium exhibits characteristic morphological and functional changes during the estrous cycle controlled by the interplay of progesterone and estradiol. A microarray analysis of endometrial tissue samples derived from 5 time points of the estrous cycle (D0, D3, D8, D12, and D16) was p...
ORGANISM(S): Equus caballus 
2012-10-23 | E-GEOD-39043 | biostudies-arrayexpress
TranscriptomicsGene expression profiling in equine polysaccharide storage myopathy
Standardized muscular biopsies of the dorsal compartment of the gluteus medius muscle were performed in 7 horses suffering from equine polysaccharide storage myopathy (PSSM) and 6 sound Norman Cob horses . Gene expression analysis was performed using an equine oligonucleotide microarray which includ...
ORGANISM(S): Equus caballus 
2009-04-08 | E-GEOD-15572 | biostudies-arrayexpress
TranscriptomicsComparison of steady state mRNA levels between equine articular cartilage and ten other equine tissues
A tissue survey of gene expression was conducted using microarray-based transcriptional profiling to compare equine articular cartilage to 10 other normal adult horse tissues. The ten comparative tissues were bladder, cerebellum, kidney, liver, lung, lymph node, muscle, placental villous, spleen, a...
ORGANISM(S): Equus caballus 
2011-01-27 | E-GEOD-23862 | biostudies-arrayexpress
UnknownTreatment outcomes for equine osteoarthritis with mesenchymal stromal cells and hyaluronic acid.
Not available
S-EPMC12326944 | biostudies-literature
TranscriptomicsIdentification of differentially expressed genes in equine endometrium at day 8 and 12 of pregnancy
In order to systematically analyze the maternal, i.e. the endometrial, changes in the equine endometrium underlying the complex embryo-maternal dialogue during early pregnancy, a transcriptome study of endometrium samples from five mares at day 8 and six mares at day 12 of early pregnancy and the co...
ORGANISM(S): Equus caballus 
2010-06-30 | E-GEOD-21046 | biostudies-arrayexpress
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