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ProteomicsProteomic differences between Drosophila melanogaster female reproductive tract tissue and fluid and their postmating responses
Fertility depends on the progression of complex and coordinated postmating processes within the extracellular luminal environment of the female reproductive tract (FRT). To achieve a more comprehensive level of knowledge regarding female-derived proteins available to interact with the ejaculate, we ...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2021-09-22 | PXD025085 | Pride
Drosophila Reproductoin Ejaculate-female interaction 
ProteomicsDrosophila female reproductive glands contribute to mating plug composition and the timing of sperm ejection
Reproductive traits that influence female remating and competitive fertilization rapidly evolve in response to sexual selection and sexual conflict. One such trait, observed across diverse animal taxa, is the formation of a structural plug inside the female reproductive tract, either during or short...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2022-01-25 | PXD028524 | Pride
Female reproductive tract Mating plug Ejaculate-female interactions Sperm ejection Spermatheca Parovaria 
TranscriptomicsTranscription profiling of Drosophila Hr39 mutant females reveals the sf1-related nuclear hormone receptor hr39 regulates Drosophila female reproductive tract development and function
The vertebrate nuclear hormone receptor steroidogenic factor 1 (SF1; NR5A1) controls reproductive development and regulates the transcription of steroid-modifying cytochrome P450 genes. We find that the SF1-related Drosophila nuclear hormone receptor HR39 is also essential for sexual development. In...
ORGANISM(S): Drosophila melanogaster 
2008-06-11 | E-GEOD-10264 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Drosophila mated females to identify mating response genes
Male-derived accessory gland proteins (Acps) that are transferred to females during mating have profound effects on female reproductive physiology including increased ovulation, mating inhibition, and effects on sperm utilization and storage. The extreme rates of evolution seen in Acps may be driven...
ORGANISM(S): Drosophila melanogaster 
2008-06-13 | E-GEOD-5012 | biostudies-arrayexpress
ProteomicsEvolutionary quantitative proteomics of reproductive interactions in Drosophila
We present data using a novel method to simultaneously identify and quantify transferred male seminal proteins and the female reproductive proteome using multiplexed Tandem-Mass-Tag (TMT) isobaric labelling of the lower female reproductive tracts dissected from virgin- or recently mated- females of ...
ORGANISM(S): Drosophila novamexicana Drosophila americana Drosophila virilis 
2023-10-24 | PXD031638 | Pride
Drosophila novamexicana Drosophila americana Tmt Sperm Seminal fluid proteins Female reproductive tract Reproductive isolation Postmating prezygotic isolation Drosophila virilis 
ProteomicsCrocodile Sperm Proteome
In a reproductive strategy that is considered unique to the mammalian lineage, spermatozoa must undergo a series of physiological changes, termed capacitation, in the female reproductive tract prior to developing their capacity to fertilize an ovum. Here, we have employed a comparative proteomic str...
ORGANISM(S): Crocodylus Porosus (ncbitaxon:8502) 
2018-04-08 | MSV000082258 | MassIVE
GenomicsMetagenome of the female upper reproductive tract
Metagenome of the female upper reproductive tract
PRJEB24147 | ENA
TranscriptomicsModified Vaccinia virus Ankara vector induces specific cellular and humoral responses in the female reproductive tract, the main HIV portal of entry
The female reproductive tract is one of the major mucosal invasion site of HIV-1. This site has been neglected in previous HIV-1 vaccine studies. Immune responses in the female reproductive tract after systemic vaccination remain to be characterized. Using a modified vaccinia virus Ankara (MVA) as a...
ORGANISM(S): Macaca fascicularis 
2017-06-09 | E-MTAB-5663 | biostudies-arrayexpress
TranscriptomicsSeminal plasma exposures strengthen vaccine responses in the female reproductive tract mucosae
HIV-1 sexual transmission occurs mainly via mucosal semen exposures. In the female reproductive tract (FRT), seminal plasma (SP) induces physiological modifications, including inflammation. An effective HIV-1 vaccine should elicit mucosal immunity. However, modifications of vaccine responses by the ...
ORGANISM(S): Macaca fascicularis 
2019-02-12 | E-MTAB-7639 | biostudies-arrayexpress
ProteomicsAbdominal-B regulates the male seminal fluid transferome and new female fecundity factors required for sperm sex peptide binding
Seminal fluid proteins determine reproductive success in a wide range of animals. In the Drosophila male accessory gland, seminal fluid is mainly produced by two cell types, a vast majority of main cells and a small number of secondary cells that are characterized by a specialized secretory apparatu...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2026-01-15 | PXD072877 | Pride
Seminal fluid Transferome Abdominal-b Drosophila melanogaster 
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