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ProteomicsDesign of a gene signature to assess the proinflammatory and the profibrotic polarization of murine fibroblasts
We provide an original multi-stage approach identifying a gene signature to assess the fibroblast polarization. Prototypic polarizations (inflammatory/fibrotic) were induced by seeded mouse embryonic fibroblasts (MEFs) with TNFα or TGFß1, respectively. The transcriptomic and proteomic profiles were ...
ORGANISM(S): Mus musculus (Mouse) 
2022-07-12 | PXD034078 | Pride
Inflammation-mediated fibrosis  fibrosis  fibroblast polarization 
TranscriptomicsModulation of the TNF-induced macrophage response by synovial fibroblasts
Here we explored how the human macrophage response to tumor necrosis factor (TNF) is regulated by human synovial fibroblasts, the representative stromal cell type in the synovial lining of joints that become activated during inflammatory arthritis. Genome-wide transcriptome analysis (RNAseq) showed ...
ORGANISM(S): Homo sapiens 
2014-08-04 | E-GEOD-57723 | biostudies-arrayexpress
UnknownSubstrate Resistance to Traction Forces Controls Fibroblast Polarization.
Not available
S-EPMC7822749 | biostudies-literature
UnknownSimple gene signature to assess murine fibroblast polarization.
Not available
S-EPMC9273630 | biostudies-literature
GenomicsBulk RNA-Seq datasets supporting fibroblast polarization drives skin regeneration versus fibrosis in adult reindeer
Bulk RNA-Seq datasets supporting fibroblast polarization drives skin regeneration versus fibrosis in adult reindeer
PRJNA713917 | ENA
GenomicsSPI1/PU.1 controls fibroblast polarization and tissue fibrosis
SPI1/PU.1 controls fibroblast polarization and tissue fibrosis
PRJNA504646 | ENA
GenomicsSingle-cell chromatin landscapes supporting fibroblast polarization drives skin regeneration versus fibrosis in adult reindeer
Single-cell chromatin landscapes supporting fibroblast polarization drives skin regeneration versus fibrosis in adult reindeer
PRJNA735968 | ENA
UnknownMerkel cell carcinoma-derived exosome-shuttle miR-375 induces fibroblast polarization by inhibition of RBPJ and p53.
Not available
S-EPMC7862059 | biostudies-literature
GenomicsSingle-cell RNA-Seq datasets supporting fibroblast polarization drives skin regeneration versus fibrosis in adult reindeer
Single-cell RNA-Seq datasets supporting fibroblast polarization drives skin regeneration versus fibrosis in adult reindeer
PRJNA598669 | ENA
UnknownJumonji domain-containing protein-3 (JMJD3) promotes myeloid fibroblast activation and macrophage polarization in kidney fibrosis.
Not available
S-EPMC12641593 | biostudies-literature
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