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ProteomicsSite-specific N- and O-glycosylation Analysis of Human Plasma Fibronectin
Human plasma fibronectin is an adhesive protein that plays a crucial role in wound healing. Many studies had indicated that glycans may mediate the expression and functions of fibronectin, yet a comprehensive understanding of its glycosylation is still missing. Here, we performed a comprehensive N- ...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD025886 | Pride
Mass spectrometer Glycosylation Stepped normalized collision energy Operator Fibronectin 
TranscriptomicsMouse myoblasts grown on Fibronectin or Collagen I for 72 hours
The goal of this study was to investigate the transcriptional regulation in cells grown on Fibronectin when compared to Collagen I 3 samples per condition
ORGANISM(S): Mus musculus 
2016-07-04 | E-GEOD-81225 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat neonatal ventricular myocytes plated in fibronectin reveals fibronectin induced cardiac myocyte hypertrophy
Gene expression changes in neonatal rat ventricular myocytes plated in fibronectin (2 samples) or uncoated plates (2 samples).
ORGANISM(S): Rattus norvegicus 
2008-06-11 | E-GEOD-1055 | biostudies-arrayexpress
ModelsBaker2017 - The role of cytokines, MMPs and fibronectin fragments osteoarthritis
Baker2017 - The role of cytokines, MMPs and fibronectin fragments osteoarthritis This model is described in the article: Mathematical modelling of cytokines, MMPs and fibronectin fragments in osteoarthritic cartilage. Baker M, Br...
2024-09-02 | BIOMD0000000928 | BioModels
ProteomicsInitiation of fibronectin fibrillogenesis is an enzyme-dependent process
Fibronectin fibrillogenesis and mechanosensing both depend on integrin-mediated force transmission to the extracellular-matrix. However, force transmission is in itself dependent on fibrillogenesis, and fibronectin fibrils are found in soft embryos where high forces cannot be applied, suggesting tha...
ORGANISM(S): Homo sapiens (Human) 
2023-04-17 | PXD040900 | Pride
Fibronectin Oxidation Lysyl oxidases 
ProteomicsInitiation of fibronectin fibrillogenesis is an enzyme-dependent process
Fibronectin fibrillogenesis and mechanosensing both depend on integrin-mediated force transmission to the extracellular-matrix. However, force transmission is in itself dependent on fibrillogenesis, and fibronectin fibrils are found in soft embryos where high forces cannot be applied, suggesting tha...
ORGANISM(S): Homo sapiens (Human) 
2023-04-17 | PXD040505 | Pride
Fibronectin Oxidation Lysyl oxidases 
TranscriptomicsFibronectin regulates Wnt7a signaling and satellite cell expansion
The influence of the extracellular matrix (ECM) within the stem cell niche remains poorly understood. We found that Syndecan-4 (Sdc4) and Frizzled-7 (Fzd7) form a coreceptor complex in satellite cells and that binding of the ECM glycoprotein Fibronectin (FN) to Sdc4 stimulates the ability of Wnt7a t...
ORGANISM(S): Mus musculus 
2014-07-11 | E-GEOD-59272 | biostudies-arrayexpress
TranscriptomicsDECREASED FIBRONECTIN PRODUCTION SIGNIFICANTLY CONTRIBUTES TO DYSREGULATED REPAIR OF ASTHMATIC EPITHELIUM
Rationale: Damage to airway epithelium is followed by deposition of extracellular matrix (ECM) and migration of adjacent epithelial cells. We have shown that epithelial cells from asthmatic children fail to heal a wound in vitro. Objectives: To determine whether dysregulated ECM production by the ep...
ORGANISM(S): Homo sapiens 
2010-04-12 | E-GEOD-18965 | biostudies-arrayexpress
GenomicsThe role of fibronectin in the post natal lens
The role of fibronectin in the post natal lens
PRJNA490544 | ENA
ProteomicsTensin3 interaction with talin drives formation of fibronectin-associated fibrillar adhesions
The formation of healthy tissue involves continuous remodelling of the extracellular matrix (ECM). Whilst it is known that this requires integrin-associated cell-ECM adhesion sites (CMAs) and actomyosin-mediated forces, the underlying mechanisms remain unclear. Here we examine how tensin3 contribut...
ORGANISM(S): Homo sapiens (Human) 
2022-09-09 | PXD026343 | Pride
Vinculin Fibronectin Tensin Talin Extracellular matrix 
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