fibrotic scar - OmicsDI

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Mus musculus (72)
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human tracheal metagenome (1)
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MLS001148580-01!6ALPHA,9ALPHA-DIFLUOROPREDNISOLONE 21-ACETATE 17-BUTYRATE (1)
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[(1S,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate (1)
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(-)-threo-Iso(homo)2-citrate;(-)-threo-1-Hydroxy-1,2,5-pentanetricarboxylic acid;1-Hydroxypentane-1,2,5-tricarboxylate;threo-(Homo)2-isocitrate (1)
(1)Benzopyrano(5,4,3-cde)(1,3)dioxolo(4,5-h)(1)benzopyran-5,11-dione, 1,2,3-trimethoxy- (1)
(1,3-Dihydroxy-6,8a-dimethyl-3-propan-2-yl-1,2,3a,4,5,8-hexahydroazulen-4-yl) 3,4-dimethoxybenzoate (1)
(10-Hydroxy-8,8-dimethyl-2-oxo-9,10-dihydropyrano[2,3-f]chromen-9-yl) (Z)-2-methylbut-2-enoate (1)
(11E)-11-Octadecenoic acid (1R,2S)-2-[[(Z)-9-hexadecenoyl]oxy]-1-methylpropyl ester (1)
(12Z)-9,10,11,14,15,16,17,18,19,20,21,22-Dodecahydro-5,8-ethenobenzo[20]annulene-2,4,6,24-tetrol (1)
(13S)-13-Ethoxy-1,2-dimethoxy-12-methyl-13H-[1,3]benzodioxolo[5,6-c]phenanthridine (1)
(14E)-11-hydroxy-14-(1H-imidazol-5-ylmethylidene)-2-methoxy-9-(2-methylbut-3-en-2-yl)-2,13,16-triazatetracyclo[7.7.0.01,13.03,8]hexadeca-3,5,7-triene-12,15-dione (1)
(14S)-9,20,21,25-Tetramethoxy-15-methyl-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.23,6.18,12.114,18.027,31.022,33]hexatriaconta-1(30),3(36),4,6(35),8,10,12(34),18,20,22(33),24,26,28,31-tetradecaen-2-one (1)
(19E,21E,23E,25E,27E,29E,31E)-17-[7-(4-aminophenyl)-5-hydroxy-4-methyl-7-oxoheptan-2-yl]-1,3,5,33,37-pentahydroxy-18,36-dimethyl-16,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-9,13,15-trione (1)
(19E,21E,23E,25E,27E,29E,31E)-17-[7-(4-aminophenyl)-5-hydroxy-4-methyl-7-oxoheptan-2-yl]-1,3,5,7,33,37-hexahydroxy-18-methyl-9,13,15-trioxo-16,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylate (1)
(1E)-4-hydroxy-1-(4-hydroxy-3-methoxyphenyl)dodec-1-en-3-one (1)
(1E,3Z)-buta-1,3-diene-1,2,4-tricarboxylate (1)
(1R)-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium-7-ol (1)
(1R)-1-[[(2S,3R,11bS)-3-ethyl-9,10-dimethoxy-1,2,3,4,5,6,7,11b-octahydrobenzo[a]quinolizin-5-ium-2-yl]methyl]-7-methoxy-1,2,3,4-tetrahydroisoquinolin-2-ium-6-ol (1)
(1R,10R)-5-amino-14-oxido-14-oxo-13,15,18-trioxa-2,4,6,9-tetraza-14lambda5-phosphatetracyclo[8.8.0.03,8.012,17]octadeca-3(8),4-diene-7,11-dione (1)
(1R,14R,24S)-24-Methoxy-5,7,19,21,25-pentaoxa-13-azahexacyclo[12.11.0.02,10.04,8.015,23.018,22]pentacosa-2,4(8),9,15(23),16,18(22)-hexaene (1)
(1R,2'S,3'aS,12S,14S)-2',12-dimethylspiro[13-oxa-2,10,17-triazatetracyclo[10.3.2.02,11.04,9]heptadeca-4,6,8,10-tetraene-14,4'-3,3a-dihydro-2H-imidazo[1,2-a]indole]-1',3,16-trione (1)
(1R,2R,5R,8R,9S,10R,11S)-11-methyl-6-methylidene-16-oxo-15-oxapentacyclo[9.3.2.15,8.01,10.02,8]heptadecane-9-carboxylate (1)

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Study type

Transcription profiling by array (9)
RNA-seq of coding RNA from single cells (3)
Spatial transcriptomics by high-throughput sequencing (2)
Single nucleus RNA sequencing (2)
RNA-seq of coding RNA (2)
Transcription profiling by SAGE (1)
Cell line - Single-cell sequencing (1)
Unknown experiment type (1)
Other (1)
ScATAC-seq (1)

Release Date

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2019 (35)
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2014 (22)
2015 (21)
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2016 (14)
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2013 (8)
2011 (7)
2012 (5)
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2010 (2)
2006 (1)
2009 (1)
2004 (1)

Lab affiliation

- Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Portugal - ICVS/3B’s Associate Lab, PT Government Associated Lab, Portugal (1)
Alfred E. Mann Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, 90089, USA Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine of USC, Los Angeles, CA, 90033, USA (1)
Department of Biochemistry and Molecular Biology, University of Calgary, Alberta, Canada; Department of Physiology and Pharmacology, University of Calgary, Alberta, Canada; The Hotchkiss Brain Institute, University of Calgary, Alberta, Canada; McCaig Institute for Bone and Joint Health, University of Calgary, Alberta, Canada. (1)
Department of Biochemistry and Molecular Genetics, School of Medicine, University of Colorado, Aurora, CO, USA (1)
Department of Oncology, University of Lausanne, Lausanne, Switzerland (1)
Helmholtz Zentrum München, Institute of Lung Biology and Disease, Group Regenerative Biology and Medicine, Munich, Germany, Member of the German Centre for Lung Research (DZL) (1)
Neufeld and Tamman Cardiovascular Research Institutes, Sheba Medical Center, Sackler School of Medicine, Tel Aviv University, Israel. (1)
Research Unit "Functional Proteomics and Metabolic Pathways", Institute of Pathology, Medical University of Graz, Stiftingtalstrasse 24, 8010 Graz, Austria; Austrian Center of Industrial Biotechnology (ACIB), Petersgasse 14, 8010 Graz, Austria, Omics Center Graz, Austria (1)
The Wellcome Centre for Cell-Matrix Research, University of Manchester, Manchester, UK (1)

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Distinct diversity of skin cell populations of rhinophyma and hypertrophic scar illustrated by scRNA-seq

The clinical manifestations and presentation of rhinophyma closely resemble those of hypertrophic scar tissue, both presenting as firm, fibrotic growths. Despite this phenotypic similarity, a critical divergence is observed following surgical intervention: the affected skin in rhinophyma can revert ...

ORGANISM(S): Homo sapiens

2026-02-18 | E-MTAB-16629 | biostudies-arrayexpress

Scar management through modulation of the fibrotic microenvironment by CAR-Trem2-macrophages

PRJNA1045715 | ENA

Fibrotic Scar in CNS Injuries: From the Cellular Origins of Fibroblasts to the Molecular Processes of Fibrotic Scar Formation.

Not available

S-EPMC9367779 | biostudies-literature

Scar management through modulation of the fibrotic microenvironment by CAR-Trem2-macrophages (scRNA-seq)

PRJNA1046508 | ENA

Hematogenous macrophage depletion reduces the fibrotic scar and increases axonal growth after spinal cord injury.

Not available

S-EPMC4323620 | biostudies-literature

Downregulation of EphB2 by RNA interference attenuates glial/fibrotic scar formation and promotes axon growth.

Not available

S-EPMC8463997 | biostudies-literature

TGF-β-induced fibrotic scar formation limits recovery of spinal cord injury.

Not available

S-EPMC12936232 | biostudies-literature

M2 macrophages mediate fibrotic scar formation in the early stages after cerebral ischemia in rats.

Not available

S-EPMC10328259 | biostudies-literature

Scar management through modulation of the fibrotic microenvironment by CAR-Trem2-macrophages (scRNA-seq)

Dipeptidyl peptidase 4 (Dpp4) plays a pivotal role in fibrotic and nonfunctional scar development following skin injury and is present in a subset of fibroblasts implicated in scar formation. Simultaneously, heterogeneous vascular endothelial cells (ECs) retain their capacity to drive tissue regener...

ORGANISM(S): Mus musculus

2024-09-24 | GSE248960 | GEO

RNAi-mediated ephrin-B2 silencing attenuates astroglial-fibrotic scar formation and improves spinal cord axon growth.

Not available

S-EPMC6492699 | biostudies-literature