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MetabolomicsGenome-scale metabolic modelling of responses to polymyxins in Pseudomonas aeruginosa
Background: Pseudomonas aeruginosa often causes multidrug-resistant infections in immunocompromised patients and polymyxins are often used as the last-line therapy. Alarmingly, resistance to polymyxins has been increasingly reported worldwide recently. To rescue this last-resort class of antibiotics...
2018-02-28 | MTBLS630 | MetaboLights
ProteomicsVibrio natriegens genome-scale modelling reveals insights into halophilic adaptations and resource allocation
Proteome profiles of Vibrio natriegens used for genome-scale metabolic modeling (GSSM). Profiling was performed across cell cultures grown aerobically on minimal medium. Cultures profiles were acquired across a range of salinities.
ORGANISM(S): Vibrio Natriegens Nbrc 15636 (ncbitaxon:1219067) 
MSV000090243 | MassIVE
ProteomicsVibrio natriegens genome-scale metabolic modelling (GSMM) reveals insights into halophilic adaptations and resource allocation
Proteome profiles of Vibrio natriegens used for genome-scale metabolic modeling (GSMM). Profiling was performed across cell cultures grown aerobically on minimal medium. Cultures profiles were acquired across a range of salinities.
ORGANISM(S): Vibrio Natriegens Nbrc 15636 (ncbitaxon:1219067) 
2023-02-07 | MSV000091219 | MassIVE
GenomicsFibroblast-specific genome-scale modelling predicts an imbalance in amino acid metabolism in Refsum disease
Fibroblast-specific genome-scale modelling predicts an imbalance in amino acid metabolism in Refsum disease
PRJNA575696 | ENA
GenomicsGenome-scale metabolic modelling uncovers cell-type specific signatures associated with APOE variants
Genome-scale metabolic modelling uncovers cell-type specific signatures associated with APOE variants
PRJNA1306066 | ENA
ProteomicsA fibroblast-specific genome-scale model focused on fatty acid alpha-oxidation
Refsum disease is an inborn error of metabolism that is characterized by a defect in peroxisomal α-oxidation of the branched-chain fatty acid phytanic acid. After clinical suspicion of this disorder, including progressive retinitis pigmentosa and polyneuropathy, Refsum disease is biochemically diagn...
ORGANISM(S): Homo sapiens (Human) 
2020-03-20 | PXD015518 | Pride
Refsum Model Human Fatty acid alpha-oxidation Fibroblasts 
TranscriptomicsGenome-Scale interrogation of the colorectal cancer methylome by Illumina HumanMethylation450 array
Colorectal cancer is an epigenetically heterogeneous disease, the extent to which is unclear. In this study we interrogate the methylome of 216 unselected colorectal cancers using Illumina HumanMethylation450 arrays, and correlate these data with transcript profiles and exome sequencing analysis to ...
ORGANISM(S): Homo sapiens 
2019-04-29 | E-MTAB-7036 | biostudies-arrayexpress
UnknownContribution of genome-scale metabolic modelling to niche theory.
Not available
S-EPMC9324083 | biostudies-literature
GenomicsGenome-wide DNA-methylation assessment by MethylCap-seq and Infinium HumanMethylation450 BeadChips: an independent large-scale comparison
DNA-methylation is an important epigenetic feature in health and disease. Two cost-efficient genome-scale methodologies to assess DNA-methylation are MethylCap-seq and Illumina's Infinium HumanMethylation450 BeadChips (HM450). However, objective information regarding the best-suited methodology for ...
EGAS00001001191 | EGA
UnknownBayesian genome scale modelling identifies thermal determinants of yeast metabolism.
Not available
S-EPMC7794507 | biostudies-literature
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