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We explored the proteomic changes in GES1 cells induced by H.pylori. GES1 cells cocultured with increasing concentrations of H.pylori were subjected to quantitative proteomic analyses using label-free methods for relative quantitation.
ORGANISM(S): Homo sapiens (Human) 
2022-02-14 | PXD025281 | Pride
We investigated the effect of H.pylori OMVs on cellular events by detecting proteomic changes in GES1 cells. GES1 cells cocultured with increasing concentrations of H.pylori OMVs were subjected to quantitative proteomic analyses using label-free methods for relative quantitation.
ORGANISM(S): Homo sapiens (Human) 
2022-02-14 | PXD025259 | Pride
Gastric Cancer AVIL overexpression and pharmacologic inhibition in GES1 and AGS cell lines.
AVIL is an oncogenic driver of gastric cancer. To test the oncogenic ability of AVIL, we established stable AVIL overexpression in normal human gastric epithelial cell line GES1 and performed RNA-sequence. We also use AVIL inhibitor compound A to treat gastric cancer cell line AGS and do transcripto...
ORGANISM(S): Homo sapiens 
2026-01-01 | GSE287892 | GEO
Time-series comprehensive DNA methylation analysis after EBV infection in the immortalised normal gastric epithelial cell line, GES1, and low methylation gastric cancer cell line, MKN7. Infinium HumanMethylation450 BeadChip was used to obtain DNA methylation profiles across 485,577 CpG sites. Sample...
ORGANISM(S): Homo sapiens 
2017-04-28 | GSE89269 | GEO
To confirm the differential regulation could occur in gastric epithelial cells as well as fibroblasts, RNA-seq analysis was performed in GES1 cells treated by pLKO lentiviral vectors expressing shRNA against non-target (shNON), TP53, and TGFBR2.
ORGANISM(S): Homo sapiens 
2025-08-13 | GSE103045 | GEO
The CpG island methylator phenotype (CIMP) is associated with prognosis and drug sensitivity in multiple cancer types. In gastric cancer, the CIMP is closely associated with Epstein-Barr virus (EBV) infection and AT-rich interactive domain 1A (ARID1A) mutations, a component of the SWI/SNF chromatin ...
ORGANISM(S): Homo sapiens 
2022-10-31 | GSE165239 | GEO
Genetic and epigenetic gene inactivation coupling with KRAS activation in human gastric cancer [RNA-Seq]
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