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MetabolomicsSex-specific effects of CD248 on metabolism and the adipose tissue lipidome

Cd248 has recently been associated with adipose tissue physiology, demonstrated by reduced weight gain in high fat diet-fed mice with genetic deletion of Cd248 relative to controls. Here we set out to determine the metabolic consequences of loss of Cd248. Strikingly, we find these to be sex speci...

2023-01-05 | MTBLS6615 | MetaboLights
TranscriptomicsLiver tissue from the "Four Core Genotype" treated group C57BL/6J mice versus pool C57BL/6J mice of chow diet Liver
The purpose of this experiment was to determine the expression traits in Liver tissue from the Four Core Genotype treated group. Keywords: Sry transgene Four Core Genotype Mouse liver Tissue Liver tissue from the "Four Core Genotype" treated group consists of 20 female and male C57BL/6J mice fed a c...
ORGANISM(S): Mus musculus 
2010-06-24 | E-GEOD-13264 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human embryonic stem cell lines HSF-1 and HSF-6 differentiated on human fetal gonadal stromal cells selected for cKIT and SSEA1 antibodies
Human embryonic stem cell lines HSF-1 and HSF-6 were differentiated on human fetal gonadal stromal cells for 7 days. The cells were labelled with antibodies against cKIT and SSEA1 and the double positive and double negative cells were collected for microarray analysis.
ORGANISM(S): Homo sapiens 
2009-06-01 | E-MEXP-1946 | biostudies-arrayexpress
TranscriptomicsLiver tissue from hormone treated C57BL/6J mice versus pool C57BL/6J mice of chow diet Liver
The purpose of this experiment was to determine the expression traits in animals of inbred strain C57BL/6J, treated with gonadal hormones. (N=40, 20 males and 20 females). Liver tissue from the hormone treated group consists of 40 female and male C57BL/6J mice fed a chow diet containing 4% fat (Rals...
ORGANISM(S): Mus musculus 
2010-06-24 | E-GEOD-13265 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of adipose tissue from mice infected with Trypanosoma brucei
The goal of this experiment was to study the alterations that occur in the adipose tissue of mice during a T. brucei infection. Gonadal adipose tissue from C57BL/6J mice infected with T. brucei AnTat 1.1E 90-13 parasites was collected at day 0 and 26 post-infection. Total RNA was extracted from 3 sa...
ORGANISM(S): Mus musculus 
2019-12-12 | E-MTAB-7596 | biostudies-arrayexpress
TranscriptomicsCaveolin-1 knockout liver and gonadal adipose tissue
mRNA expression was compared in between wild type and caveolin-1 knockout livers mRNA expression was compared in between wild type and caveolin-1 knockout gonadal adipose tissue RNA was isolated from livers from male mice in at the light phase RNA was isolated from gonadal adipose tissues from male ...
ORGANISM(S): Mus musculus 
2012-01-31 | E-GEOD-35431 | biostudies-arrayexpress
TranscriptomicsGonadal Adipose Tissue Profiling In HMDP (high-fat/high-sucrose diet)
Identify genes in the gonadal adipose tissue whose expression is under genetic regulation in the Hybrid Mouse Diversity Panel (HMDP). The HMDP comprises classical inbred and recombinant inbred wild type mice. The RMA values of genes were used for genome wide association as described in Parks et al...
ORGANISM(S): Mus musculus 
2015-01-08 | E-GEOD-64768 | biostudies-arrayexpress
GenomicsTranscriptome profiling of human gonadal tissue in Differences of Sex Development
Transcriptome profiling of human gonadal tissue in Differences of Sex Development
PRJNA1414663 | ENA
TranscriptomicsSubcutaneous and gonadal adipose tissue transcriptome differences in lean and obese female dogs
Adipose, once considered an inert storage depot, is now known to be an active endocrine tissue involved in total body homeostasis and metabolism, which exerts effects on multiple systems including food intake, immune function, and blood glucose regulation. Adipose tissue depots are known to have un...
ORGANISM(S): Canis lupus familiaris 
2012-01-15 | E-GEOD-29280 | biostudies-arrayexpress
TranscriptomicsmiRNA profiling in male and female chicken embryonic gonads during sexual differentiation
MicroRNAs (miRNAs) are a highly conserved class of small RNAs which function in a sequence-specific manner to post-transcriptionally regulate expression of target genes. Tissue-specific miRNA expression studies have discovered numerous functions for miRNAs in various aspects of embryonic developmen...
ORGANISM(S): Gallus gallus 
2010-05-18 | E-GEOD-13154 | biostudies-arrayexpress
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