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hACE2 transgenic mice were infected with the original SARS-CoV-2 strain (B.1) and the Beta (B.1.351) variant. Lung and spleen samples were collected 1 day post infection (DPI), 3 DPI and 5 DPI, and mRNA was sequenced.
ORGANISM(S): Mus musculus 
Mouse metagenome strain:K18-hACE2 Raw sequence reads
Responses to SARS-CoV-2 variants in hACE2 transgenic mice
Transcriptomic analysis of hippocampus of hACE2 mice with SARS-CoV-2 infection
Effect of Mac1 deletion mutant of SARS-CoV-2 infection of K18-hACE2 mice
Eight 10-week-old female K18-hACE2 mice were equally divided into control (n = 4) and virus-infected group (n = 4). Mice in the virus-infected group were challenged with 10^5 median tissue culture infective dose (TCID50) of SARS-CoV-2 virus by intranasal inoculation and mice in the control group wer...
ORGANISM(S): Mus Musculus 
2022-07-21 | PXD035474 |
Transcriptional profiling of lungs from SARS-CoV-2-infected K18-hACE2 mice
Delta (B1.617.2) variant of SARS-CoV-2 induces severe neurotropic patterns in K18-hACE2 mice
RNA-seq Analysis of wild type, hACE2 and hCD147 mice lung tissues Transcriptomes after infection with SARS-CoV-2
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