Sort   by:  
 Page size 
ProteomicsEarly response of C2C12 myotubes to a sub-cytotoxic dose of hemorrhagic metalloproteinase HF3 from Bothrops jararaca venom
Manifestations of local tissue damage, such as hemorrhage and myonecrosis, are among the most dramatic effects of envenomation by viperid snakes. Snake venom metalloproteinases (SVMPs) of the P-III class are main players of the hemorrhagic effect due to their activities in promoting blood vessel dis...
ORGANISM(S): Mus musculus (Mouse) 
2019-02-25 | PXD011274 | Pride
C2c12 myotubes  hf3  snake venom metalloproteinase  peptidomics  proteomics 
ProteomicsA systemic view of active site specificity profiling of the snake venom metalloprotease HF3 using Proteomic Identification of Cleavage Sites and N-terminomics TAILS
Snake venom metalloproteinases play important roles in the pathological effects of Viperidae venoms including severe local tissue damage, hemorrhage and coagulopathy. Hemorrhagic Factor 3 (HF3), a metalloproteinase isolated from Bothrops jararaca venom, induces severe local hemorrhage. Previous prot...
ORGANISM(S): Mus musculus (Mouse) 
2019-07-29 | PXD009201 | Pride
N-terminome Snake venom metalloprotease Snake venom Hf3 Tails Degradomics 
ProteomicsSystemic effects of hemorrhagic snake venom metalloproteinases: untargeted peptidomics to explore the pathodegradome of plasma proteins
In this study we investigated the proteolysis of human plasma proteins by HF3, an hemorrhagic metalloproteinase from B. jararaca venom. For this purpose, approaches for the depletion of the most abundant proteins and for the enrichment of low abundant proteins of human plasma were used to minimize t...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD027997 | Pride
Bothrops  snake venom  hemorrhagic factor 3 (hf3)  human plasma  degradome 
ProteomicsSystemic toxicity of snake venom metalloproteinases: proteomics analyses of kidney injury and blood plasma disturbances in a mouse model
Metalloproteinases are abundant in viperid venoms and are implicated in several envenomation effects. Bothrops jararaca venom is reported to induce kidney injury and coagulopathy. HF3 is an extremely hemorrhagic metalloproteinase from B. jararaca venom and participates in the local pathogenesis of e...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-01-20 | MSV000091101 | MassIVE
UnknownCleavage of proteoglycans, plasma proteins and the platelet-derived growth factor receptor in the hemorrhagic process induced by snake venom metalloproteinases.
Not available
S-EPMC7395112 | biostudies-literature
UnknownSystemic Effects of Hemorrhagic Snake Venom Metalloproteinases: Untargeted Peptidomics to Explore the Pathodegradome of Plasma Proteins.
Not available
S-EPMC8622078 | biostudies-literature
UnknownHigh Fat Diet Administration during Specific Periods of Pregnancy Alters Maternal Fatty Acid Profiles in the Near-Term Rat.
Not available
S-EPMC4728639 | biostudies-literature
GenomicsMus musculus strain:Swiss
Systemic activity of HF3, a snake venom metalloproteinase, in Mus musculus.
PRJNA930140 | ENA
GenomicsBos indicus x Bos taurus
Small RNA sequencing
PRJNA1147473 | ENA
GenomicsMus musculus
A human-like fat diet is sufficient to induce transgenerational obesity
PRJNA116213 | ENA
Sort   by:  
 Page size