high grade serous cancer

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Unknown (2272)
Genomics (861)
Transcriptomics (466)
Proteomics (131)
Other (31)
Methylation profiling (23)
Multiomics (8)
Clinical (7)
Metabolomics (7)
Genomic (4)

Organisms

Homo sapiens (816)
Mus musculus (81)
synthetic construct (2)
unidentified plasmid (1)

Organisms

Homo sapiens (458)
Mus musculus (59)
mouse metagenome (1)

Repository

ENA (607)
geo (453)
EGA (190)
biostudies-arrayexpress (128)
pride (105)
MassIVE (12)
PeptideAtlas (8)
dbGaP (4)
iProX (4)
MetabolomicsWorkbench (4)
ExpressionAtlas (3)
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PanoramaPublic (2)
GNPS (1)

Tissue

Epithelial cell (33)
Cell culture (25)
Ovarian serous carcinoma cell (12)
Ovary (12)
Ovarian surface epithelial cell (8)
Ovary cancer cell (7)
Fibroblast (6)
Female Reproductive System (5)
Ascites (5)
Epithelial ovarian cancer cell (5)
Stromal cell (5)
Ovary (3)
Blood plasma (3)
Blood serum (3)
Malignant cell (3)
Ovary epithelium (3)
Primary cell (3)
Blood (2)
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Cell suspension culture (2)
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Oviduct epithelium (2)
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T cell (2)
Whole body (2)
Ovaries (1)
Ovarian cancer cells (1)
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Cyst (1)

Disease

Acute myeloid leukemia (1)
Acute promyelocytic leukemia (1)
Adenosquamous lung carcinoma (1)
Adrenal gland neuroblastoma (1)
Adult B acute lymphoblastic leukemia (1)
Adult T acute lymphoblastic leukemia (1)
Adult T-cell leukemia/lymphoma (1)
Adult acute megakaryoblastic leukaemia (1)
Adult acute monocytic leukemia (1)
Adult acute myeloid leukemia (1)
Alveolar rhabdomyosarcoma (1)
Amelanotic melanoma (1)
Ampulla of Vater adenocarcinoma (1)
Anaplastic astrocytoma (1)
Anaplastic large cell lymphoma (1)
Askin tumor (1)
Astrocytoma (1)
Atypical teratoid rhabdoid tumor (1)
B-cell acute lymphoblastic leukemia (1)
B-cell non-Hodgkins lymphoma (1)
B-cell prolymphocytic leukemia (1)
Barrett adenocarcinoma (1)
Basaloid squamous cell carcinoma (1)
Bladder carcinoma (1)
Burkitts lymphoma (1)
Epstein-Barr virus-related Burkitt lymphoma (1)
Ewing sarcoma (1)
Hodgkins lymphoma (1)
Mantle cell lymphoma (1)
T-cell acute lymphoblastic leukemia (1)

Technology Type

Mass Spectrometry (109)
Shotgun proteomics (61)
Bottom-up proteomics (30)
Data-independent acquisition (10)
Data-dependent acquisition (8)
Affinity purification coupled with mass spectrometry proteomics (6)
Top-down proteomics (6)
ESI (3)
Illumina HiSeq 2500, ILLUMINA (2)
DiaPASEF (2)
Gel-based experiment (2)
SRM/MRM (2)
SWATH MS (2)
Illumina HiSeq 2500, ILLUMINA, Illumina MiSeq, HiSeq X Ten (1)
ILLUMINA, Illumina HiSeq 2500, NextSeq 500, Nanostring (1)
Illumina HiSeq2000 (1)
Illumina MiSeq, ILLUMINA (1)
Complete Genomics (COMPLETE_GENOMICS) (1)
Illumina MiSeq, Illumina HiSeq 2500 (1)
Aperio (1)
ILLUMINA, Illumina HiSeq 2500, Illumina HiSeq 2000 (1)
Illumina Genome Analyzer, Illumina HiSeq 2000, Illumina MiSeq, Affymetrix_U133plus2- (1)
Illumina HiSeq 2000, ILLUMINA, Illumina HiSeq 2500 (1)
AB SOLiD 4 System (1)
Illumina HiSeq 2000, Illumina Genome Analyzer II, ILLUMINA (1)
Illumina HiSeq 2000 (1)
Illumina Genome Analyzer II (1)
Mass spectrometry (1)
Mass spectrometry assay (1)
MALDI (1)

Instrument Platform

LTQ Orbitrap Velos (9)
Q Exactive (8)
Illumina HiSeq 1500 (7)
NextSeq 500 (4)
Illumina NovaSeq 6000 (3)
Illumina HiSeq 2000 (3)
Q Exactive HF (3)
NextSeq 550 (2)
Liquid Chromatography MS - positive - reverse phase (2)
QIAcube (Qiagen) (1)
EpMotion 5075 automated pipetting system (Eppendorf, Hamburg, Germany) (1)
Illumina Genome Analyzer IIx (1)
Illumina Genome Analyzer II (1)
DNBSEQ-G400 (1)
Illumina HiSeq 4000 (1)
Compact (1)
Agilent 6550 QTOF (1)
Autoflex II (1)
Orbitrap Fusion Lumos (1)
QExactive Classic (1)
TimsTOF fleX (1)
Liquid Chromatography MS - alternating - reverse phase (1)
Liquid Chromatography MS - negative - reverse phase (1)
Liquid Chromatography MS - alternating - hilic (1)
QExactive (1)

Publication Date

2025 (94)
2026 (86)
2020 (74)
2024 (60)
2023 (52)
2021 (48)
2022 (47)
2016 (39)
2014 (38)
2019 (35)
2015 (35)
2018 (20)
2011 (19)
2017 (18)
2013 (17)
2012 (17)
2009 (6)
2008 (4)
2006 (4)
2010 (2)
2005 (1)

UNIPROT ID/AC

A0A024RC46 (8)
A0A087WT59 (8)
A0A087WTX5 (8)
A0A087WVW2 (8)
A0A087WYL9 (8)
A0A087X130 (8)
A0A087X1V9 (8)
A0A087X232 (8)
A0A0A0MS07 (8)
A0A0A0MS51 (8)
A0M8Q6 (8)
A0N5G5 (8)
A2BFH1 (8)
A2NUT2 (8)
A4F255 (8)
A5A3E0 (8)
A6NHL2 (8)
A6NNZ2 (8)
B1AHL2 (8)
B2RPK0 (8)
B3KML9 (8)
B4DHB3 (8)
B4DKM5 (8)
B4DPR2 (8)
B4DRF2 (8)
B4DRV9 (8)
B4DY08 (8)
B4E3A4 (8)
B5ME49 (8)
B7Z556 (8)

ENSEMBL ID

ENSG00000229353 (8)
ENSG00000170477 (7)
ENSG00000204131 (7)
ENSG00000147251 (6)
ENSG00000247315 (6)

CHEBI ID

CHEBI:52117 (1)
CHEBI:191950 (1)
CHEBI:22194 (1)
CHEBI:18077 (1)
CHEBI:44409 (1)
CHEBI:16284 (1)
CHEBI:28850 (1)
CHEBI:68568 (1)
CHEBI:28939 (1)
CHEBI:36314 (1)
CHEBI:17111 (1)
CHEBI:17625 (1)
CHEBI:28846 (1)
CHEBI:15633 (1)
CHEBI:18406 (1)
CHEBI:17230 (1)
CHEBI:16668 (1)
CHEBI:35621 (1)
CHEBI:45658 (1)
CHEBI:20794 (1)
CHEBI:16311 (1)
CHEBI:30818 (1)
CHEBI:70857 (1)
CHEBI:24298 (1)
CHEBI:16436 (1)
CHEBI:21626 (1)
CHEBI:7676 (1)
CHEBI:8087 (1)
CHEBI:18349 (1)
CHEBI:17755 (1)

Metabolite Name

Lysotracker Red DND-99 (1)
Glycine 13C2-15N (1)
2-Hydroxybutyric acid (AHB) (1)
Carbamoyl Aspartate (1)
Asymmetric dimethylarginine (ADMA) (1)
Alpha-Ketoglutarate (aKG) (1)
S-Adenosyl-L-methionine (SAM) (1)
Gamma-aminobutyric acid (GABA) (1)
Formiminoglutamic acid (FIGLU) (1)
5-Hydroxyindole-3-Acetate (1)
S-Adenosyl-L-Homocysteine (SAH) (1)
Cis-urocanic acid (1)
Erythrose 4-phosphate (1)
Deoxycytidine (1)
C17 Sphinganine-1-phosphate (1)
P-Aminobenzoate (1)
Deoxyadenosine (1)
DGTP (1)
DATP (1)
DTTP (1)
PRPP (1)
Trans-urocanic acid (1)
DUTP (1)
DGDP (1)
Deoxyguanosine (1)
Deoxyuridine (1)
TMAO (1)
Folate (1)
Dihydroxyacetone phosphate (1)
Cis-aconitate (1)

First Public Date

2025 (92)
2024 (81)
2026 (76)
2020 (74)
2022 (54)
2021 (50)
2014 (45)
2023 (41)
2019 (27)
2015 (23)
2016 (18)
2018 (12)
2017 (9)
2013 (3)
2011 (2)

Study status

Recruiting (4)
Active, not recruiting (3)

Study type

Transcription profiling by array (68)
RNA-seq of coding RNA (24)
Comparative genomic hybridization by array (13)
Methylation profiling by array (7)
Interventional (6)
ChIP-seq (5)
Unknown experiment type (3)
Human - High-throughput sequencing (2)
Genotyping by array (2)
MicroRNA profiling by array (2)
Cell line - High-throughput sequencing (1)
RNA-seq of coding RNA from single cells (1)
Observational (1)

Release Date

2022 (277)
2025 (268)
2023 (266)
2024 (247)
2021 (236)
2020 (232)
2019 (162)
2016 (142)
2018 (126)
2017 (104)
2015 (92)
2014 (74)
2026 (43)
2013 (42)
2012 (38)
2011 (21)
2010 (10)
2008 (7)
2009 (6)
2006 (4)
2005 (2)

Lab affiliation

Cancer Biology Department, Fox Chase Cancer Center, Philadelphia, PA, USA (4)
Director of Women’s Health Research Women’s Service Line Inova Health System (3)
Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver V5Z 1L3, Canada. (2)
Cancer Research UK Beatson Institute, Glasgow, UK (2)
Proteomics core facility, Biomedical Research Institute, Seoul National University Hospital (2)
University of Copenhagen Faculty of Health and Medical Sciences Novo Nordisk Foundation Center for Protein Research Proteomics Program (2)
Associate Professor, Centre for Biosystems Science and Engineering, IISC Bangalore, India (1)
BRIC-National Centre for Cell Science, Inside Pune Univesrity, Ganeshkhind, Pune, India, 411007 (1)
Bertis R&D Division, Bertis Inc., Republic of Korea (1)
Brown University (1)
CRUK - Beatson Institute for Cancer Research - Switchback Rd, Bearsden, Glasgow G61 1BD - United Kingdom (1)
Cancer Biology Program, Fox Chase Cancer Center, Philadelphia, PA, USA (1)
Centre for Genomics and Computational Biology Barts Cancer Institute Queen Mary University of London John Vane Science Centre, Charterhouse Square, London EC1M 6BQ (1)
Clinical Research Division, Fred Hutchinson Cancer Research Center (1)
Department of Biochemistry, Siebens Drake Research Institute, Western University (1)
Department of Cell Biology, Microbiology, and Molecular Biology University of South Florida Tampa, FL, USA 33620 (1)
Department of Chemistry, Univeristy of Kansas, Lawrence, KS, USA (1)
Department of Chemistry, University of Illinois Chicago, Chicago, USA (1)
Department of Convergence Medicine, Convergence Medicine Research Center/Biomedical Research Center, Asan Medical Center, Asan Institute for Life Sciences, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Republic of Korea. (1)
Department of Gastroenterology, Hepatology and Clinical Oncology, Medical Center for Postgraduate Education; Warsaw, Poland Department of Genetics, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology; Warsaw, Poland (1)
Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas (1)
Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv 69978, Israel (1)
Department of Integrated Immunobiology Duke School of Medicine Durham, NC, USA (1)
Department of Laboratory Medicine & Pathology, University of Minnesota (1)
Department of Laboratory Medicine and Pathology University of Minnesota School of Medicine (1)
Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, MN 55455 USA (1)
Department of Laboratory Medicine and Pathology, University of Minnesota School of Medicine, Minneapolis, Minnesota 55455, USA (1)
Department of Laboratory Medicine and Patholoogy, University of Minnesota. Minneapolis, MN, USA (1)
Department of Life Sciences, University of Mdoena and Reggio Emilia (1)
Department of Medical Oncology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. (1)

Location

United States (3)
Canada (2)
Guam (1)
Australia (1)
United Kingdom (1)

Keyword

Personalized patient-derived xenografts (pPDX) (1)
Drug sensitivity testing (1)
Serous (1)
KIF18A Inhibitor (1)
Mitogens (1)
Triple negative (1)
Fludarabine (1)
Cyclophosphamide (1)
Interleukin-2 (1)
Metastatic (1)
Ipilimumab (1)
Molecular profiling (1)
Epigenetic analysis (1)
Nivolumab (1)
Primary Prevention (1)

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Deep Metabolomics of a High-Grade Serous Ovarian Cancer Triple Knockout Mouse Model.

Not available

ORGANISM(S): Mus musculus

ST001172 | MetabolomicsWorkbench

Time-Resolved Metabolomics of a Mouse Model of High-Grade Serous Ovarian Cancer (MSI)

Not available

ORGANISM(S): Mus musculus

ST002083 | MetabolomicsWorkbench

Metabolomic Fingerprinting of Human High Grade Serous Ovarian Carcinoma Cell Lines

Not available

ORGANISM(S): Homo sapiens

ST001983 | MetabolomicsWorkbench

Time-Resolved Metabolomics of a Mouse Model of Ovarian High-Grade Serous Carcinoma (LC-MS)

Not available

ORGANISM(S): Mus musculus

ST002067 | MetabolomicsWorkbench

Profiles of genomic instability in high-grade serous ovarian cancer (HGSC) predict treatment outcome

Profiling of loss of heterozygosity (LOH) in HGSC, subcrouping HGSC by LOH-based clustering and comparing to the LOH profiles of triple-negative breast cancer [previously submitted; GSE19594]. Study for the correlation of LOH burdern and LOH-based subgroups to clinical response to platinum-based ch...

ORGANISM(S): Homo sapiens

2012-11-06 | E-GEOD-39130 | biostudies-arrayexpress

miRNA profiling in high-grade serous ovarian carcinoma

In this study, we performed miRNA profiles analysis of high-grade serous ovarian carcinoma compared to normal fallopian tube fimbria using microarray (Exiqon, Denmark) to evaluate their potential role in the pathogenesis of uterine leiomyoma. miRNA profiling analysis of the 10 samples including 5 h...

ORGANISM(S): Homo sapiens

2014-11-14 | E-GEOD-61485 | biostudies-arrayexpress

BRAF Mutation Is Rare in Advanced-Stage Low-Grade Ovarian Serous Carcinomas

Low-grade ovarian serous carcinomas are believed to arise via an adenoma-serous borderline tumor-serous carcinoma sequence. In this study, we found that advanced-stage, low-grade ovarian serous carcinomas both with and without adjacent serous borderline tumor shared similar regions of loss of hetero...

ORGANISM(S): Homo sapiens

2011-03-04 | E-GEOD-27659 | biostudies-arrayexpress

Neoadjuvant chemotherapy modulates T cell responses in high-grade serous ovarian cancer metastases

Our data suggest that neoadjuvant chemotherapy enhances anti-cancer responses of T cells in peritoneal metastases of patients with high-grade serous ovarian cancer but does not decrease levels of immune checkpoint molecules, providing a rationale for sequential chemo-immunotherapy. tRNA was isolated...

ORGANISM(S): Homo sapiens

2016-07-27 | E-GEOD-71340 | biostudies-arrayexpress

Discovery and validation of serum glycoprotein biomarker panel for detection of high grade serous ovarian cancer

We aimed to discover and validate a panel of serum biomarkers for high grade serous ovarian cancer (HGSOC) using our lectin-magnetic bead array-coupled proteomics platform. Serum from age-matched women with HGSOC, benign tumours or healthy controls were analysed in discovery (UKCTOCS, n=30 and UKOPS...

ORGANISM(S): Homo Sapiens

2024-08-06 | PXD033108 | panorama

Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer

Explore This Study at the NCI Proteomic Data Commons

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2019-08-28 | MSV000084246 | MassIVE

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