Sort   by:  
 Page size 
TranscriptomicsExpression data from hiPSCs-NSCs towards 4T1
Neural stem cells can migrate towards tumors of both neural and non-neural origins, which is crucial for the success in treating disseminated tumors. Although the understanding of the molecular mechanisms underlying NSC tumor tropism is limited, it has been noted that several cytokines, growth facto...
ORGANISM(S): Homo sapiens 
2013-02-28 | E-GEOD-40750 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression analysis of human iPSC-derived Neural Stem Cells (NSC) from LCA patients and unaffected persons
Our purpose was to investigate genes and molecular mechanisms involved in patients with Leber congenital amaurosis (LCA). Fibroblasts from two unrelated clinically-identified patients (Coriell) were reprogrammed to pluripotency by retroviral transduction. These human induced Pluripotent Stem Cells (...
ORGANISM(S): Homo sapiens 
2015-01-21 | E-GEOD-43924 | biostudies-arrayexpress
ProteomicsQuantitative proteomics for efficient differentiation of human induced pluripotent stem cells into neural stem cells using data independent acquisition mass spectrometry.
Human induced pluripotent stem cells were differentiated into NSC for 7 days. Cells on days 0, 1, 2, 3, 5 and 7 of differentiation (2.0 × 10⁶) were washed twice with DPBS (−) and then mixed with 100 μL of dissolution buffer consisting of 12 mM sodium deoxycholate, 12 mM N-lauroylsarcosine, 100 mM Tr...
ORGANISM(S): Homo Sapiens (human) 
2022-06-27 | PXD034925 | JPOST Repository
TranscriptomicsCompare gene expression profiles of mouse iNSC, WT-NSC, and MEF
The iNSC cells are two clones generated from the same MEF line. Therefore, we conducted one analysis that compared the two clonal lines and a separate analysis that compared iNSC vs. NSC, iNSC vs. MEF, and NSC vs. MEF. Both were single factor ANOVAs, the first compared two groups (the iNSC lines) ...
ORGANISM(S): Mus musculus 
2012-06-06 | E-GEOD-37859 | biostudies-arrayexpress
UnknownhiPSC-derived NSCs effectively promote the functional recovery of acute spinal cord injury in mice.
Not available
S-EPMC7953804 | biostudies-literature
UnknownExtracellular vesicles from hiPSC-derived NSCs protect human neurons against Aβ-42 oligomers induced neurodegeneration, mitochondrial dysfunction and tau phosphorylation.
Not available
S-EPMC12008877 | biostudies-literature
UnknownhiPSC-derived neural stem cells from patients with schizophrenia induce an impaired angiogenesis.
Not available
S-EPMC5821759 | biostudies-literature
UnknownIntranasal Human NSC-Derived EVs Therapy Can Restrain Inflammatory Microglial Transcriptome, and NLRP3 and cGAS-STING Signalling, in Aged Hippocampus.
Not available
S-EPMC12884020 | biostudies-literature
ProteomicsMicroenvironment remodeling during human iPSC-derived NSC 3D differentiation
Brain microenvironment plays an important role in neurodevelopment and function, where extracellular matrix (ECM) components and soluble factors modulate cellular features, as migration, proliferation survival and neuronal function. Disruption of microenvironment’s homeostasis is often related to pa...
ORGANISM(S): Homo sapiens (Human) 
2018-07-31 | PXD007130 | Pride
3d cultures  neual differentiation  hipsc-derived nsc  ecm  microenvironment  swath 
UnknownCombined transplantation of hiPSC-NSC and hMSC ameliorated neuroinflammation and promoted neuroregeneration in acute spinal cord injury.
Not available
S-EPMC10916262 | biostudies-literature
Sort   by:  
 Page size