Sort   by:  
 Page size 
TranscriptomicsA cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells
Dendritic cells (DC) serve a key function in host defense, linking innate detection of microbes to the activation of pathogen-specific adaptive immune responses. Whether there is cell-intrinsic recognition of HIV-1 by host innate pattern-recognition receptors and subsequent coupling to antiviral T c...
ORGANISM(S): Homo sapiens 
2010-09-09 | E-GEOD-22589 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human cells transfected with MLV and HIV1 virus-like particles
We hypothesize that cellular mRNAs are incorporated nonselectively into retrovirus particles Experiment Overall Design: This study utilizes microarray analysis to test these hypotheses. Transfected cells were grown, RNA was isolated and used for global gene expression profiling (Affymetrix Human U13...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7213 | biostudies-arrayexpress
ProteomicsDetermination of Gag stoichiometry for different production platforms by PRM analysis
In this work we established an analytical method of characterization for the Gag protein core and clarify the current variability of Gag stoichiometry in HIV-1 VLPs depending on the cell-based production platform, directly determining the number of Gag molecules per VLP in each case. Three Gag pepti...
ORGANISM(S): Homo sapiens (Human) 
2022-12-07 | PXD021278 | Pride
Absolute quantitative proteomics gag  hiv-1 virus-like particles  prm 
TranscriptomicsA3G and A3F CLIP
APOBEC3G and APOBEC3F are cell-encoded restriction factors that have evolved to counteract virus infections. When packaged into HIV-1 particles, A3G and A3F impair reverse transcription and induce the hypermutation of viral DNA. We employed a next generation sequencing approach to identify the RNAs ...
ORGANISM(S): Homo sapiens 
2014-12-17 | E-MTAB-2700 | biostudies-arrayexpress
UnknownHIV-1-based Virus-like Particles that Morphologically Resemble Mature, Infectious HIV-1 Virions.
Not available
S-EPMC6630479 | biostudies-literature
GenomicsA tissue-intrinsic mechanism sensitizes HIV-1 particles for TLR-triggered innate immune responses
A tissue-intrinsic mechanism sensitizes HIV-1 particles for TLR-triggered innate immune responses
PRJNA1327907 | ENA
UnknownImmunological Characterization of Plant-Based HIV-1 Gag/Dgp41 Virus-Like Particles.
Not available
S-EPMC4795674 | biostudies-literature
UnknownBiological and biochemical characterization of HIV-1 Gag/dgp41 virus-like particles expressed in Nicotiana benthamiana.
Not available
S-EPMC3688661 | biostudies-literature
UnknownImmunogenicity of HIV-1-Based Virus-Like Particles with Increased Incorporation and Stability of Membrane-Bound Env.
Not available
S-EPMC8002006 | biostudies-literature
UnknownHIV-1 virus-like particles produced by stably transfected Drosophila S2 cells: a desirable vaccine component.
Not available
S-EPMC3416305 | biostudies-literature
Sort   by:  
 Page size